Study Finds More Effective Treatment for Pneumonia Following... ( McCullers said. The damage process wa...)

Study Finds More Effective Treatment for Pneumonia Following Influenza

Date:1/8/2009

," McCullers said. "The damage process was continuing."

McCullers said he would like the new findings to influence treatment guidelines immediately for pneumonia secondary to influenza.

"The current guidelines still adhere to the theory that beta-lactams are the only drugs of choice, because it is necessary to kill the bacteria as fast as possible," he said. "However, our findings represent the first data showing that inflammation is important, and that alternative therapies such as protein synthesis inhibitors should be considered and incorporated into revised guidelines."

More broadly, McCullers said, the new findings support a growing body of evidence that treating severe pneumonia in general should take into account the inflammatory response and not just the rapid demise of bacteria.

Other authors of this paper include Asa Karlstrom and Kelli Boyd (St. Jude); and B. Keith English (Le Bonheur Children's Medical Center). This research was supported in part by the U.S. Public Health Service and ALSAC.

St. Jude Children's Research Hospital

St. Jude Children's Research Hospital is internationally recognized for its pioneering work in finding cures and saving children with cancer and other catastrophic diseases. Founded by late entertainer Danny Thomas and based in Memphis, Tenn., St. Jude freely shares its discoveries with scientific and medical communities around the world. No family ever pays for treatments not covered by insurance, and families without insurance are never asked to pay. St. Jude is financially supported by ALSAC, its fundraising organization. For more information, please visit www.stjude.org.

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