Navigation Links
Study Finds Molecular Link Between Obesity, Hypertension
Date:12/17/2008

as a potential anti-obesity medication, though this study was not assessing its effect on weight loss. Instead, the team looked at the drug's effect on blood pressure in 28 obese individuals (none of whom were MC4R-deficient).

What they observed was an acute, dose-dependent increase in blood pressure upon drug treatment, Farooqi said. "So, basically what this means is that both our own data on the patients with the MC4R gene problem, and the data from Lilly giving the drug, show that this gene is important in controlling blood pressure."

Most people, of course, are not missing the MC4R gene. What normally happens in obese individuals, Farooqi explained, is this: "As people gain weight, they make more fat. And your fat produces a hormone called leptin, and levels of leptin then increase. Leptin then circulates in the bloodstream and goes to the brain, where it triggers MC4R, which then triggers the sympathetic system, and drives up your blood pressure."

Dr. Daniel Marks, of the Oregon Health & Science University in Portland, said, "It is a well-done study and teaches us something about the fundamental physiology of blood pressure regulation in humans."

Yet Marks also cautioned that MC4R is not likely the only link between obesity and blood pressure.

"There's a difference between being statistically significant and clinically significant," he said. "Those are two different issues, and I think the issue of clinical significance is still pretty unknown here."

Dr. George Bakris, of the University of Chicago Pritzker School of Medicine, called the study a "really big deal."

"I think this paper is going to become a real classic," Bakris said, "because it is the first time this kind of characterization has been done in such a very clean way and provides a way of identifying people who may not have a blood pressure problem, even though they may have a weight problem."

Bakris sugges
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study Finds Molecular Link Between Obesity, Hypertension
(Date:5/23/2015)... (PRWEB) May 23, 2015 On May ... powers of a youngster's yogic power learned through meditation ... Nithyananda Swami in Bangalore, India. , Yogamaatha, a nine-year-old ... than 50 high profile professionals attending the 2015 Business ... reading fluently -- blindfolded. , In a demonstration ...
(Date:5/23/2015)... May 23, 2015 Manufacturers are now required ... Factor (HSPF) of 8.2. Experts in the field agree that ... consumers. , The HSPF score is what miles per gallon ... efficient the unit. Although the minimum HSPF score has been ... with an HSPF score north of 12. Indeed, the regulation ...
(Date:5/22/2015)... 22, 2015 The world is ... capacity are intersecting to create new opportunities for ... opening speaker at WesternU's 34th annual Commencement Exercises ... Gavin Newsom, a former San Francisco mayor and ... at the graduation ceremony for WesternU's colleges of ...
(Date:5/22/2015)... New York (PRWEB) May 22, 2015 ... ) filed on behalf of individuals who allegedly ... to its use continue to move forward in ... According to a Pretrial Order dated May 4, ... preservation of documents and electronically stored information. Among ...
(Date:5/22/2015)... MA (PRWEB) May 22, 2015 ... Hart, MS/CCC, SLP, RAC-CT, CHHRP-QT, Vice President of ... “A very important ‘language’ that impacts how care ... the leader in long term care reimbursement, operations ... education programs and talent management, launches a new ...
Breaking Medicine News(10 mins):Health News:Nine-Year-Old Reads Blindfolded at Business Advocacy Summit 2Health News:Nine-Year-Old Reads Blindfolded at Business Advocacy Summit 3Health News:Parker & Sons Welcomes the Department of Energy’s Water Heater Regulation 2Health News:Newsom to WesternU Grads: The Future is Inside You 2Health News:Newsom to WesternU Grads: The Future is Inside You 3Health News:Court Overseeing Federal Xarelto Lawsuits Establishes Procedures Governing Preservation of Documents, Electronically Stored Information 2Health News:Court Overseeing Federal Xarelto Lawsuits Establishes Procedures Governing Preservation of Documents, Electronically Stored Information 3Health News:Court Overseeing Federal Xarelto Lawsuits Establishes Procedures Governing Preservation of Documents, Electronically Stored Information 4Health News:Harmony Healthcare International Takes the Lead in Launching ICD-10 Coding Transition in Post-Acute Care 2Health News:Harmony Healthcare International Takes the Lead in Launching ICD-10 Coding Transition in Post-Acute Care 3
... , Bargaining Agreement Reached , PHILADELPHIA, ... Local #929 will return to work today after voting to ... Red Cross Penn-Jersey Blood Region. , (Logo: ... who pack, ship and deliver blood to hospitals, assist at ...
... ... AHD International, a distributor of new-to-market nutraceutical ... of relaxation category brand leader Purple Stuff, has announced that ... weight loss, maintain healthy cholesterol levels already within the normal ...
... , , , LOS ANGELES, ... " presentation is being telecast over multiple broadcasts, cable and ... homes this year. Participating stars and other notables include Celine ... Kidman, Bob Costas, and Natalie Cole. , (Photo: http://www.newscom.com/cgi-bin/prnh/20091223/DC30052 ...
... , CLASS Act Long-Term Care Provision Key to ... of the National Council on Aging: , WASHINGTON, Dec. 23 ... Protection and Affordable Care Act (H.R. 3590), which, when passed, will ... health care that is both accessible and affordable for Americans of ...
... factor E2F1 reduced epidermal growth factor receptor (EGFR) expression ... metastatic melanoma cells, according to a brief communication published ... National Cancer Institute . To investigate E2F1,s role ... the department of vectorology and experimental gene therapy at ...
... protection, experts say, , WEDNESDAY, Dec. 23 (HealthDay News) ... the holidays can have a dark side, with asymptomatic ... , "Kids get colonized by strep and pneumococcus, and ... sick from it, but the elderly are more susceptible ...
Cached Medicine News:Health News:American Red Cross Announces End to Teamsters Strike 2Health News:AHD International & Funktional Beverages, Inc Launch Red Stuff™ with LuraLean 2Health News:Top Stars Rally for Fighting Blindness, Sending Their Message out to 160 Million Homes on Multiple Cable Networks, December 25th, Preceded by President George Herbert Walker Bush Describing the Frank Capra Classic, 'It's A Wonderful Life' for the Bl 2Health News:NCOA Supports Senate Health Reform Bill 2Health News:NCOA Supports Senate Health Reform Bill 3Health News:Kids Can Pass Pneumonia Bug to Older Relatives During Holidays 2
(Date:5/22/2015)... Richmond Pharmacology is a ... a worldwide reputation for excellence in clinical trials. ... peer reviewed medical journals. Its officers are engaged ... discussions about rules for transparency and publication of ... , Clinical research is conducted worldwide, ...
(Date:5/22/2015)...  China Nepstar Chain Drugstore Ltd. (NYSE: NPD ) ... in China based on the ... of Mr. Fuxiang Zhang as the Company,s ... Rebecca Yingnan Zhang has been appointed as ... effective immediately. Meanwhile, Ms. Zhang resigned from the position ...
(Date:5/21/2015)... May 21, 2015  When Ryan Rendino ... side of his neck, he figured it ... couple weeks off from weight lifting. ...                               A series of ... referred to Michel Kliot, MD , ...
Breaking Medicine Technology:China Nepstar Chain Drugstore Ltd. Announces Management Change and New Director Appointment 2China Nepstar Chain Drugstore Ltd. Announces Management Change and New Director Appointment 3Northwestern Medicine Surgeons Develop New Approach to Removing Nerve Tumors 2Northwestern Medicine Surgeons Develop New Approach to Removing Nerve Tumors 3Northwestern Medicine Surgeons Develop New Approach to Removing Nerve Tumors 4
Phacoemulsification system is a complete anterior segment surgical instrument. Its simplified design and unique innovations provide optimal surgical performance....
Aaron Burr II with disposable 1mm burr for corneal rust ring removal and a diamond burr tip for polishing the pterygium bed after surgical removal and for lid margin lesions....
Algerbrush II corneal rust ring remover battery powered...
Non-Illuminated Trial Lens Set with lenses mounted in plastic frames....
Medicine Products: