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Study Finds Discontinuation of Rosiglitazone Left Many Diabetes Patients Without Good Glycemic Control
Date:4/14/2009

ahey Clinic, respectively, emphasized that patients who discontinue TZD's are at risk for higher fasting blood glucose and hemoglobin A1c levels, as reported by Fanning et al, which might further their cardiovascular risk. Furthermore, they point out that 5 large prospective studies have not found that rosiglitazone has any more cardiovascular risk than placebo or other hypoglycemic drugs and that a recent meta-analysis has also shown that TZD's do not increase cardiovascular mortality.

Resources

Link to April EP issue: http://aace.metapress.com/openurl.asp?genre=issue&issn=1530-891X&volume=15&issue=3

Link to Commentary:

http://media.aace.com/images/84/Fanning weissman.pdf

Link to Editorial:

http://media.aace.com/images/84/April Ep Editorial.pdf

About Endocrine Practice

Endocrine Practice, a peer-reviewed journal published seven times a year, is the official journal of the American College of Endocrinology (ACE) and the American Association of Clinical Endocrinologists (AACE). The primary mission of Endocrine Practice is to enhance the health care of patients with endocrine diseases through continuing education of practicing endocrinologists. More information about the journal can be found at

SOURCE American Association of Clinical Endocrinologists
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