Navigation Links
Study Finds Discontinuation of Rosiglitazone Left Many Diabetes Patients Without Good Glycemic Control
Date:4/14/2009

JACKSONVILLE, Fla., April 14 /PRNewswire-USNewswire/ -- When concerns were raised about the safety of the diabetes medication, rosiglitazone, in May 2007, many patients and their doctors made the decision to discontinue use of the drug. A study published today in Endocrine Practice by Dr. Etta Fanning from the University of Texas Health Science Center along with her colleagues reported that many patients who discontinued use of rosiglitazone received less therapy and higher blood glucose levels as a result.

(Logo: http://www.newscom.com/cgi-bin/prnh/20090324/DC88061LOGO-b)

A meta-analysis published in 2007 showed an increased risk of cardiovascular disease and myocardial infarction for patients using rosiglitazone. After that data was published, the FDA placed a black box warning on both thiazolidinediones (TZD) on the market, rosiglitazone and pioglitazone.

The study published in Endocrine Practice today entitled Clinical Practice Impact of Rosiglitazone Discontinuation on Glycemic Control shows that 89% of patients in the study group were using combination therapy before discontinuing use of rosiglitazone. After discontinuation, only 33% of patients were on a combination therapy. Another 13% of the group were not prescribed any diabetes medication at all.

The glycemic control of the group was also impacted after discontinuing rosiglitazone. In patients who received combination therapy, and who had laboratory values in both pre- and post-discontinuation periods, significant increases were observed in both fasting blood glucose and A1c.

In an accompanying Editorial, cardiologists Drs. Stuart Zarich and Dr. Richard Nesto, from Yale Medical School and L
'/>"/>

SOURCE American Association of Clinical Endocrinologists
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Study reports success in treating a rare retinal disorder
2. Low Blood Sugar Events Increase Dementia Risk in Elderly Patients With Type 2 Diabetes, Kaiser Permanente Study Finds
3. Avoiding No Mans Land: New Deloitte Study on Follow-on Biologics Investigates Proposed Legislation and Possible Unintended Consequences
4. Impotence Drugs Dont Harm Vision: Study
5. Three Medical Centers Awarded Funds to Study Generation of Cardiac Muscle Cells
6. National Physicians Study: Nearly One Third Would Choose Different Career Today
7. Ex-White House Drug Czar McCaffrey, U.S. Congress Drug Caucus Chair Cummings, CRC Health CEO Karlin Join Hopkins Researchers at News Conference April 17 on Breakthrough Study: Internet Video Drug Treatment as Effective as Traditional Counseling
8. Study of neighborhoods points to modifiable factors, not race, in cancer disparities
9. New alternative to biopsy detects subtle changes in cancer cells, Stanford study shows
10. Study Challenges Link Between Panic Attacks, PTSD
11. Study assesses new surgical procedure for regenerating cartilage in damaged knee joints
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2015)... ... July 29, 2015 , ... According to The Spirits Business ... is directly responsible for stimulating and perpetuating alcohol use disorders. Humans have the same ... of the National academy of Sciences, and has given researchers inklings to explore Rsu1 ...
(Date:7/29/2015)... ... 29, 2015 , ... According to the Miami Herald on July ... mental health disorders. Acu-detox may begin taking off in the South Florida community as ... addiction. Although acupuncture is not a new practice, it is not widely used, but ...
(Date:7/29/2015)... ... July 29, 2015 , ... San Fernando Valley skin doctor , Dr. ... time only, patients can get the complete treatment process with a 10 percent discount ... non-invasive treatment and have loose or sagging skin. , As the only non-surgical ...
(Date:7/29/2015)... ... 2015 , ... Today marks a significant achievement in bringing new monies into ... is led by a group of experienced investors, has tapped into an investor community ... to be a part of the fund. The Sofia Fund II is now ...
(Date:7/29/2015)... ... , ... CanAm Enterprises, LLC (“CanAm”) is thrilled to announce that more than ... been granted to investors in four different CanAm EB-5 projects -- the Sony and ... and the Valley Forge Convention Center project in CanAm’s regional center in partnership with ...
Breaking Medicine News(10 mins):Health News:Study Reveals Potential for Gene Manipulation to Stop Alcohol Addiction 2Health News:Study Reveals Potential for Gene Manipulation to Stop Alcohol Addiction 3Health News:Miami Drug Rehab Introduces Acupuncture to Line of Holistic Healing for Addiction 2Health News:Miami Drug Rehab Introduces Acupuncture to Line of Holistic Healing for Addiction 3Health News:San Fernando Valley Dermatology Office, Castle Dermatology Institute, is Now Offering a Promotional Price on Ultherapy 2Health News:Sofia Fund Surpasses Investor Goals 2Health News:More Than 60 New I-829 Approvals in Less Than 30 days for CanAm 2Health News:More Than 60 New I-829 Approvals in Less Than 30 days for CanAm 3
... happen to posses a certain gene mutation, your risks of ... question is a specific variation for hereditary hemochromatosis. This is ... affects how the body metabolizes iron, which results an iron ... condition causes liver enlargement that can lead to cirrhosis or ...
... reduced blood glucose levels in obese diabetic mice, ... a new study from Japan. ,"Dietary ... of hyperglycaemia in diabetic obese mice," wrote lead ... dietary intake of food or drinks produced from ...
... we are familiar with terms like ‘grumpy old man’, ‘old fogies’ ... Colorado University//. Surprisingly, it’s older people who are more optimistic about ... as they get older, and it is the young who tend ... , As part of a survey of 150 persons, the subjects ...
... chemicals that can keep arteries healthy and prevent heart ... least one orange// a day could keep cardiac disease ... that reduced blood cholesterol levels by 20-25 percent during ... Daily Mail. ,The researchers at the Hebrew ...
... stress better than those live single, says a study that ... perception is that single people have a carefree lifestyle. But ... makes it easier to cope with the stresses and strains ... ,Psychologist Dr Roxane Gervais monitored the stress levels of ...
... researchers at Weill Cornell Medical College could prove a potent ... compound, called SS31, is able to cross the blood-brain barrier ... tissue damage. ,"In our experiments, we found that ... to a much smaller area of brain tissue being affected," ...
Cached Medicine News:Health News:Gene Mutation Linked With Risks of Stroke 2Health News:Cocoa Polyphenols may Offer Diabetes Benefits - Study 2Health News:Antioxidant Molecule Could Help Minimize Stroke-Linked Brain Damage 2
(Date:7/29/2015)... SAN DIEGO , July 29, 2015 /PRNewswire/ ... Thursday, July 23, called the Alvarado Spine & ... orthopedic surgery and rehabilitation, focusing on spinal surgery ... method of patient care takes a patient experience-focused ... whatever clothing they feel comfortable in, rather than ...
(Date:7/29/2015)... , July 29, 2015  Cryoport, ... the "Company"), the leading provider of advanced ... industry, serving markets including immunotherapies, stem cells, ... animal health, and reproductive medicine, announced today ... of common stock and warrants (the "Units") under a ...
(Date:7/29/2015)... N.J. , July 29, 2015  Ortho-Clinical Diagnostics, ... five assays under development. The assays address a range ... kidney injury and cardiac troponin I. The scientific posters ... Clinical Chemistry Annual Meeting to be held July 26 ...   "Ortho Clinical Diagnostics is emerging stronger ...
Breaking Medicine Technology:The Alvarado Spine & Joint Institute Opens July 30 in San Diego 2Cryoport Completes $6.8 Million Equity Capital Raise 2Cryoport Completes $6.8 Million Equity Capital Raise 3Ortho-Clinical Diagnostics, Inc. Presents Data On Five Assays In Development At American Association For Clinical Chemistry Annual Meeting 2Ortho-Clinical Diagnostics, Inc. Presents Data On Five Assays In Development At American Association For Clinical Chemistry Annual Meeting 3
... Mass., Oct. 22 Repligen Corporation (Nasdaq: RGEN ... for the second quarter of fiscal year 2011, on Tuesday, ... and Chief Executive Officer, Walter C. Herlihy, Ph.D., will host ... 3:00 p.m. EDT, to discuss the financial results and provide ...
... Oct. 22 The American College of Emergency Physicians, ... is educating the public about safe disposal of expired, ... the threat of drug abuse by children.  Seventy percent ... got them from friends or relatives and a recent ...
Cached Medicine Technology:Repligen Announces Conference Call of Second Quarter Fiscal Year 2011 Results Tuesday, November 2nd, 3:00 p.m. EDT 2Repligen Announces Conference Call of Second Quarter Fiscal Year 2011 Results Tuesday, November 2nd, 3:00 p.m. EDT 3Emergency Physicians Urge Americans to Take The American Medicine Chest Challenge November 13th 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: