Navigation Links
Study Finds Aspirin Still Best at Preventing 2nd Stroke
Date:5/25/2011

WEDNESDAY, May 25 (HealthDay News) -- A new drug that had shown promise in animal testing is not better than aspirin in preventing a second stoke in someone who's already had one, a new study has found.

In fact, researchers stopped the study early because the drug, terutroban, showed no extra benefit.

Previous research in animals had suggested that the drug was as effective as aspirin at preventing blood clots, and scientists had wondered whether it might have other positive effects on the human cardiovascular system.

The new study, by Dr. Marie-Germaine Bousser, of the Lariboisiere Hospital in Paris and her colleagues, compared the drug to aspirin in people who'd had an ischemic stroke, the type of stroke caused by a blocked artery. Of the more than 19,000 participants, roughly half were assigned to take terutroban, and the others took aspirin.

When tracked, on average, for the next 28 months, people who took terutroban fared no better than those on aspirin, the study found.

"In a worldwide perspective, aspirin remains the gold standard antiplatelet drug for secondary stroke prevention, in view of its efficacy, tolerance and cost," the researchers wrote.

One expert agreed.

"Allowing for the 'gentler' conclusion that there is no difference between terutroban and aspirin for stroke prevention, aspirin remains a widely available and inexpensive treatment throughout the world," said Dr. Richard B. Libman, chief of the division of vascular neurology at Long Island Jewish Medical Center in New Hyde Park, N.Y. "Any new medication for stroke prevention is going to have to do better than this before it can replace 'good old' aspirin," he said.

But in a commentary, researchers from Chang Gung University College of Medicine in Taiwan and the University of California, San Diego, wrote that there's still more to learn about whether terutroban could help people who have had a second stroke while on aspirin.

"Trials that randomly assign patients with a breakthrough event while on aspirin to a newer antiplatelet drug or higher aspirin dose, rather than re-initiation of the original aspirin dose, could provide insights into this issue," they wrote. "Perhaps terutroban could be called on to perform again."

The study, published online May 25 in The Lancet, was also to be presented Wednesday in Hamburg, Germany, at the European Stroke Conference.

More information

The U.S. National Heart, Lung, and Blood Institute has more about stroke.

-- Randy Dotinga

SOURCE: Richard B. Libman, MD FRCP(C), chief, division of vascular neurology, Long Island Jewish Medical Center, New Hyde Park, NY; The Lancet, news release, May 25, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Research study reveals profile for female drunk-drivers
2. Pelvic widening continues throughout a persons lifetime, UNC study
3. US study shows that tofacitinib is an efficacious treatment for active RA
4. Study finds much different work histories for disability rejects, beneficiaries
5. Study Ties Blood Markers to Death Risk in Heart Failure
6. Temple-led study finds widening gap between distracted driving and legislation
7. Brisk walking may help men with prostate cancer, UCSF study finds
8. New study aims to improve long-term treatment for patients with bipolar disorder
9. Medicare improved Canadian doctors salaries: Queens University study
10. IUPUI study first to look at early treatment of depression to reduce heart disease risk
11. A Cultured Man Is a Healthier, Happier Man: Study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study Finds Aspirin Still Best at Preventing 2nd Stroke
(Date:5/26/2017)... ... ... the Garden of Eden”: retells the stories of three Bible figures in modern terms. ... Colt, mother, trader, horse farmer, artist and a former GM journeyman. Born in 1953 ... they moved to Dayton, Ohio, where Penny graduated high school. At sixteen, she toured ...
(Date:5/26/2017)... ... 26, 2017 , ... Water damage to the flooring of several classrooms at ... education officials with a number of critical issues to address before students could return ... accomplished with little or no disruption to class schedules. Second, the project had to ...
(Date:5/24/2017)... ... 24, 2017 , ... In modern research, success depends greatly ... for research and understanding the basic principles that were designed to drive that ... in stereo microscopy for brightfield and fluorescence typically used in laboratories working on ...
(Date:5/24/2017)... ... May 24, 2017 , ... Altec Products, Inc., a leader in ... a one-day technology conference in San Diego, CA. , At nVerge 2017, Altec ... fully utilize and enhance their Sage ERP solutions by providing improved visibility and control ...
(Date:5/24/2017)... (PRWEB) , ... May 24, 2017 , ... ... dental implants in Bayside, NY, who have now spent 10 years as clinical ... New York University (NYU) College of Dentistry. Through the program, private practitioners receive ...
Breaking Medicine News(10 mins):
(Date:5/22/2017)... May 22, 2017  Lilac Corp, the company ... the launch of a new website . ... of a clinical study that showed surprising clearance ... Gene-Eden-VIR/Novirin in individuals suffering from HPV warts, precancerous, ... there are no other treatments that clear the ...
(Date:5/18/2017)...  Two Bayer U.S. Pharmaceutical leaders received top awards ... 28 th Woman of the Year ... longstanding mission of furthering the advancement and impact of ... Cindy Powell-Steffen , senior director of brand activation and ... Libby Howe , a regional business manager for New ...
(Date:5/15/2017)... -- Amy Baxter MD, chief executive officer and founder of ... was awarded a 2017 Top 40 Healthcare Transformer designation ... the MM&M Top 40 Healthcare Transformers dinner and awards ... May 10, 2017. The dinner followed a full-day conference ... pill."  "Innovation goes beyond invention," noted Baxter ...
Breaking Medicine Technology: