Navigation Links
Study Examines Link Between Breast Cancer and Diabetes
Date:12/13/2012

THURSDAY, Dec. 13 (HealthDay News) -- Postmenopausal breast cancer survivors are at increased risk for developing diabetes and should be screened for the disease more closely, a new study suggests.

Researchers analyzed data from 1996 to 2008 from the province of Ontario, Canada, to determine the incidence of diabetes among nearly 25,000 breast cancer survivors aged 55 or older and nearly 125,000 age-matched women without breast cancer.

During a median follow-up of more than five years, nearly 10 percent of all the women in the study developed diabetes. Compared to those who had not had breast cancer, the risk of diabetes among breast cancer survivors was 7 percent higher two years after cancer diagnosis and 21 percent higher 10 years after cancer diagnosis, the investigators found.

The risk of diabetes, however, decreased over time among breast cancer survivors who had undergone chemotherapy. Their risk compared to women without breast cancer was 24 percent higher in the first two years after cancer diagnosis and 8 percent higher 10 years after cancer diagnosis, according to the study, which was published Dec. 12 in the journal Diabetologia.

"It is possible that chemotherapy treatment may bring out diabetes earlier in susceptible women," study author Dr. Lorraine Lipscombe, of Women's College Hospital and Women's College Research Institute in Toronto, said in a journal news release. "Increased weight gain has been noted [after receiving] chemotherapy for breast cancer, which may be a factor in the increased risk of diabetes in women receiving treatment."

"Estrogen suppression as a result of chemotherapy may also promote diabetes," Lipscombe added. "However, this may have been less of a factor in this study where most women were already postmenopausal."

The study authors suggested that there may be other factors involved for women who received chemotherapy, including glucocorticoid drugs, which are used to treat nausea in patients receiving chemo and are known to cause spikes in blood sugar. In addition, breast cancer patients undergoing chemotherapy are monitored more closely and thus are more likely to have diabetes detected, they noted.

The researchers said it is unclear why diabetes risk increased over time among breast cancer survivors who did not receive chemotherapy.

"There is, however, evidence of an association between diabetes and cancer, which may be due to risk factors common to both conditions," Lipscombe said. "One such risk factor is insulin resistance, which predisposes to both diabetes and many types of cancer -- initially insulin resistance is associated with high insulin levels and there is evidence that high circulating insulin may increase the risk of cancer."

"However, diabetes only occurs many years later when insulin levels start to decline," she said. "Therefore, it is possible that cancer risk occurs much earlier than diabetes in insulin-resistant individuals, when insulin levels are high."

Overall, the "findings support a need for closer monitoring of diabetes among breast cancer survivors," Lipscombe concluded.

Although the study found an association between diabetes and breast cancer, it did not prove a cause-and-effect relationship.

More information

The American Cancer Society outlines what happens after breast cancer treatment.

-- Robert Preidt

SOURCE: Diabetologia, news release, Dec. 12, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. Study reveals how cancer drug causes diabetic-like state
3. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
4. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
5. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
6. No Added Cancer Risk From Hip Replacement Materials: Study
7. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
8. Early Study Finds Some Promise for Lung Cancer Vaccine
9. Narcissists Often Ace Job Interviews, Study Finds
10. Sexual objectification of female artists in music videos exists regardless of race, MU study finds
11. Soy may alleviate hot flashes in menopause, large-scale study finds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study Examines Link Between Breast Cancer and Diabetes
(Date:6/25/2016)... , ... June 25, 2016 , ... Conventional wisdom preaches ... success. In terms of the latter, setting the bar too high can result in ... than just slow progress toward their goal. , Research from PsychTests.com ...
(Date:6/24/2016)... ... ... was in a crisis. Her son James, eight, was out of control. Prone to extreme ... “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was ... other children and say he was going to kill them. If we were driving ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited ... To Recovery® program to drive cancer patients to and from their cancer treatments. ... highest quality of life and ongoing independence. Getting to and from medical treatments ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute ... Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s newest ... world, and the most handsome men, look naturally attractive. Plastic surgery should be ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) ... held on June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, ... dedicated to helping service members that have been wounded in battle and their families. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016 Dehaier Medical Systems Ltd. (NASDAQ: ... markets and sells medical devices and wearable sleep respiratory ... strategic cooperation agreement with Hongyuan Supply Chain Management Co., ... June 20, 2016, to develop Dehaier,s new Internet medical ... Dehaier will leverage Hongyuan Supply Chain,s sales platform to ...
(Date:6/24/2016)... , June 24, 2016 ... Market by Type (Standard Pen Needles, Safety Pen Needles), ... (Insulin, GLP-1, Growth Hormone), Mode of Purchase (Retail, Non-Retail) ... MarketsandMarkets, This report studies the market for the forecast ... to reach USD 2.81 Billion by 2021 from USD ...
(Date:6/24/2016)...  Arkis BioSciences, a leading innovator in the ... cerebrospinal fluid treatments, today announced it has secured ... led by Innova Memphis, followed by Angel Capital ... Arkis, new financing will accelerate the commercialization of ... of its in-licensed Endexo® technology. ...
Breaking Medicine Technology: