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Study Evaluating Efficacy and Safety of Two Low-dose Regimens of PREMARIN Vaginal Cream for the Treatment of Moderate to Severe Vaginal Atrophy Now Published
Date:7/13/2009

atment emergent AE's were headache, infection, arthralgia and vaginitis.

About PREMARIN Vaginal Cream

PREMARIN Vaginal Cream is used to treat menopausal changes in and around the vagina and painful intercourse caused by these changes.()Menopause can cause changes in the vaginal tissue, resulting in uncomfortable symptoms. PREMARIN Vaginal Cream treats the underlying cause of many of these symptoms and can restore the tissues that provide elasticity and lubrication with a low-dose and low-cream volume. PREMARIN Vaginal Cream is only available by prescription.

Important Safety Information:

What is the most important information you should know about PREMARIN Vaginal Cream (an estrogen mixture)?

Estrogens may increase the chance of getting cancer of the uterus.

Report any unusual vaginal bleeding right away while you are using PREMARIN Vaginal Cream. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your health care professional should check any unusual vaginal bleeding to find out the cause.

Do not use estrogens with or without progestins to prevent heart disease, heart attacks, strokes, or dementia.

Using estrogens, with or without progestins, may increase your chance of getting heart attacks, strokes, breast cancer, and blood clots. Using estrogens, with or without progestins, may increase your chance of getting dementia, based on a study of women age 65 years or older. You and your health care professional should talk regularly about whether you still need treatment with PREMARIN Vaginal Cream.

PREMARIN((R) )(conjugated estrogens) Vaginal Cream is used after menopause to treat menopausal changes in and around the vagina and to treat painful intercourse caused by menopausal changes of the vagina.

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SOURCE Wyeth Pharmaceuticals
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