Navigation Links
Study Disproves Belief That Hepatitis C Blunts HIV Drugs

Impaired immune response after antiretroviral therapy may be due to genetic factors

FRIDAY, July 25 (HealthDay News) -- A new study challenges the long-held belief that the hepatitis C virus (HCV) impairs the immune system's ability to restore itself after HIV patients are treated with highly active antiretroviral therapy (HAART).

From 50 percent to 90 percent of HIV-infected drug users are also infected with HCV. Intravenous drug use is the main cause of both types of infection.

Researchers at Wake Forest University Baptist Medical Center focused on levels of CD4 cells -- the immune cells that are attacked by HIV -- and whether CD4 cells can rebuild after HAART is used to suppress HIV infection. For the study, the researchers analyzed the medical records of 322 patients.

"We've been observing that in some patients that are co-infected with hepatitis C, we were treating their HIV with HAART but didn't always get very good restoration of CD4," lead researcher Dr. Marina Nunez, an assistant professor of infectious diseases, said in a Wake Forest news release. "Some studies have suggested it was because of the hepatitis C. This study says it's not the presence of active hepatitis C replication."

She said impaired immune restoration seen in some HIV/HCV-infected patients after HAART may be due to a number of other causes, such as genetic factors involved in immune system regulation, confounding factors associated with HCV acquisition, or other unknown factors.

"Research efforts should pursue the role of those other factors in the immune restoration," Nunez said.

"From a clinical standpoint, although these findings will not alter the clinical management of HIV-HCV-co-infected patients, they make clear that even after successful treatment of the HCV infection, some patients may not get an adequate CD4 recovery under HIV treatment," she said.

The study was published in the July issue of AIDS Research and Human Retroviruses.

More information

The U.S. National Institute of Allergy and Infectious Diseases has more about HIV treatment.

-- Robert Preidt

SOURCE: Wake Forest University Baptist Medical Center, news release, July 25, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
(Date:12/1/2015)... ... 01, 2015 , ... TCS Healthcare Technologies (TCS), a leading ... arenas, is pleased to announce that VIP Care Services, a Caprock Health Group ... ACUITY Complete Care™ Management to back their collaborative catastrophic case management initiatives. ACUITY ...
(Date:12/1/2015)... Park, CA (PRWEB) , ... December 01, 2015 , ... ... (XTC) has selected 10 semi-finalists to head to Las Vegas for CES 2016, the ... judges including CEO of Consumer Technology Association Gary Shapiro, Founding Partner of Pacific Investments ...
(Date:12/1/2015)... ... December 01, 2015 , ... With FCPX Overlay: ... with full control over customization, the possibilities are truly endless, all with a click ... overlay depth position, vertical flip, horizontal flip, depth of field and more, all within ...
(Date:12/1/2015)... ... December 01, 2015 , ... Dr. ... a Modern Man for 2015. , Angeleno Magazine is a division of ... Established in 1994, Modern Luxury includes more than 50 magazine titles across 15 ...
(Date:12/1/2015)... (PRWEB) , ... December 01, 2015 , ... ... Contact Center Enterprise Authorized Technology Provider (ATP) status from Cisco. This designation recognizes ... and support Cisco Unified Contact Center solutions targeted to the high-end enterprise contact ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... and BOCA RATON, Fla. ... for the Commercialization of Public Research (the Institute) ... with KynderMed , a medical device start-up company ... supports new company creation based on publicly-funded research, and ... Florida -based universities and research institutions. ...
(Date:11/30/2015)...  Kevin Smith has been appointed Chief Commercial ... in wireless monitoring of vital signs.  As CCO ... Mr. Smith will be responsible for the development ... will also directly oversee partnering with US hospitals ... SensiumVitals, the first early warning detection device to ...
(Date:11/30/2015)... -- Oramed Pharmaceuticals Inc. (NASDAQ: ORMP ), a ... drug delivery systems, announced today it has signed definitive ... Incubator of Technologies Co., Ltd. ("HTIT") for exclusive rights ... China , Hong Kong ... were signed at the Israel Knesset (Parliament). ...
Breaking Medicine Technology: