Study Determines Breast-Specific Gamma Imaging Has Higher Specificity Than MRI in Patients With Equivocal ...(coil. The sensitivity specificity positi...),Health

Date:10/2/2007

coil. The sensitivity, specificity, positive and negative predictive values were calculated for both BSGI and MRI. Statistical significance was determined by comparing the confidence interval of each parameter for BSGI and MRI. All imaging findings were correlated with pathologic diagnosis.

BSGI versus MRI

In the study, thirty-three indeterminate lesions were evaluated. There were a total of 9 pathologically confirmed cancers in 8 patients. Breast MRI resulted in 18 false positive cases while BSGI demonstrated only 7. There was no statistically significant difference in sensitivity of cancer detection between BSGI and MRI. BSGI demonstrated a greater specificity than MRI, 71 percent and 25 percent, respectively.

The study authors concluded, BSGI has comparable sensitivity and greater specificity than MRI for the detection of breast cancer in patients with equivocal mammograms. The smallest cancer detected by BSGI was 3 mm.

Details about BSGI with the Dilon 6800 Gamma Camera

Breast-Specific Gamma Imaging (BSGI), performed with the Dilon 6800, is a molecular breast imaging technique that can see lesions independent of tissue density and thereby discover very early stage cancers. For difficult-to-diagnose patients, BSGI serves as a complementary diagnostic adjunctive procedure to mammography and ultrasound. With BSGI, the patient receives a radioactive tracing agent that is absorbed by all the cells in the body. Cancerous cells in the breast, due to their increased rate of metabolic activity, absorb a greater amount of the tracing agent than normal, healthy cells and generally appear as "hot spots" on BSGI images.

BSGI is ideal for patients with mammograms that are difficult to interpret. The interpretation challenges include dense breast tissue; suspicious areas on a mammogram; lumps that can be felt but not seen with mammography or ultrasound; implants and breast augmentation; scarring from previous surgeries and for women with no
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SOURCE Dilon Technologies Copyright©2007 PR Newswire. All rights reserved

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