Navigation Links
Study Describes Molecules That Control Blood Pressure
Date:11/2/2007

n by stimulating production of WNK4, Ellison said. The extra WNK4 reduces the activity of WNK3. The entire complex of three WNK kinases also acts as a unit, modifying the activity of the NCC protein.

"What happens is that WNK4 normally inhibits WNK3, reducing salt resorption," Ellison said. "Mutant WNK4 blocks this effect, thereby generating more active WNK3, increasing salt transport and causing hypertension."

The WNK kinases are members of one of the largest protein families in the human body. There are 518 of them, coordinating a wide variety of biological functions. The WNK kinases, which were discovered in 2000, have been objects of research since a group led by Dr. Richard P. Lifton, who heads his own laboratory at Yale University, found a link between them and a rare inherited form of high blood pressure, called familial hyperkalemic hypertension.

Lifton had no immediate comment on the new report.

The new research is still at a basic level, Ellison said. "If we develop a new pharmaceutical approach to hypertension, that could be helpful," he added.

More information

A guide to lowering high blood pressure is offered by the U.S. National Heart, Lung, and Blood Institute.



SOURCES: David H. Ellison, M.D., professor, medicine, Oregon Health & Science University, Portland; Nov. 1, 2007, Journal of Clinical Investigation


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Rural Canadians travel far for specialists: study
2. A new study surpasses Gene Therapy Hurdle
3. Tomato Sauce reduces Cancer Risk- Study
4. A question on study of Adult Stem Cell
5. Study on obesity and heart failure
6. National Lung Study in the process
7. Marijuana gateway theory strengthened by study of twins
8. Old theory of adaptation confirmed by new study
9. Study casts doubt on keyboard ills
10. Gene study links endometriosis, infertility
11. Study reveals how stress can make you sick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... BCC Research ( http://www.bccresearch.com ) reveals ... DETECTORS: TECHNOLOGIES AND GLOBAL MARKETS , the global ... grow to $15.2 billion by 2019, with a ... Increasing industrialization is driving significant growth across ... range of industrial applications such as military and ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 It’s no ... abuse. According to the National Institute on Drug Abuse, ... illicit drugs. What’s even more alarming is the fact ... the last decade. , Those locked in a struggle ... a way out. But now, the newly-redesigned AbuseTreatmentCenters.net has ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 The finalists ... a leading health-marketing industry trade magazine, will honor the ... Trailblazer Awards are given to outstanding companies, marketers and ... offer. , “We are proud to announce that ... to entries with double the number of submissions we ...
(Date:8/20/2014)... NY (PRWEB) August 20, 2014 ... largest nutrition school, is proud to announce its ... Studies (CIIS), a cutting-edge university offering graduate ... Health Coach Training Program are now eligible to ... Arts in Integrative Health Studies. , “I’m so ...
(Date:8/20/2014)... Little Green Pouch today announced the launch ... —to meet growing demand for eco-friendly products that make ... , “The Real Food movement is really gaining ... She continues, “Parents want to choose exactly what they ... pesticides and hidden ingredients in commercially prepared foods. But ...
Breaking Medicine News(10 mins):Health News:Global Market for Photonic Sensors and Detectors to Reach $15.2 Billion in 2019 2Health News:Global Market for Photonic Sensors and Detectors to Reach $15.2 Billion in 2019 3Health News:Re-Launched AbuseTreatmentCenters.net Offering New List of Substance Abuse Resources 2Health News:PM360 Announces 2014 Trailblazer Award Finalists 2Health News:PM360 Announces 2014 Trailblazer Award Finalists 3Health News:PM360 Announces 2014 Trailblazer Award Finalists 4Health News:PM360 Announces 2014 Trailblazer Award Finalists 5Health News:PM360 Announces 2014 Trailblazer Award Finalists 6Health News:PM360 Announces 2014 Trailblazer Award Finalists 7Health News:PM360 Announces 2014 Trailblazer Award Finalists 8Health News:Integrative Nutrition Announces New Partnership with California Institute of Integral Studies 2Health News:Integrative Nutrition Announces New Partnership with California Institute of Integral Studies 3Health News:Little Green Pouch Launches New Product to Help Health-conscious Parents Reduce Babies’ Eco-footprint 2
... the greater the chances , TUESDAY, May 4 (HealthDay ... her baby,s risk of developing psychiatric problems in childhood ... While there,s plenty of evidence that smoking during pregnancy ... such as asthma, ear infections and respiratory disease, this ...
... In an ... Program will be moving into a bigger office location on April 26. , ... Cincinnati, OH (PRWEB) May 4, 2010 -- The continued success ... facility away from their existing location on Pine Road in Kenwood. The office now occupies a ...
... ... LLP have again been named as Ohio Super Lawyers®. This honor, by the much respected ... accomplished medical malpractice attorneys. Congratulations! , ... Cleveland, OH (PRWEB) May 4, 2010 -- Spangenberg lawyers were again honored this ...
... ... prognostic testing system for individual patients announces new publications in major disease conditions validating ... US catch-up? , ... Michigan (Vocus) May 4, 2010 -- PrognostiCheck®, the noninvasive assessment of the presence, severity ...
... for providing better care to patients could end up ... belonging to racial and ethnic minorities, according to a ... a typical pay-for-performance program medical practices that serve vulnerable ... a result of existing gaps in the quality of ...
... experts add that painkiller,s other health benefits may outweigh possible ... British study finds that people who take aspirin every day ... devastating digestive illness. , But it,s still not very likely ... lead author said patients should keep in mind that aspirin ...
Cached Medicine News:Health News:Smoking While Pregnant May Raise Psychiatric Risks in Kids 2Health News:Smoking While Pregnant May Raise Psychiatric Risks in Kids 3Health News:UniqueU Medical Weight Loss Success Requires an Expansion and Move to a Larger Location 2Health News:Cleveland Attorneys Recognized as Ohio Super Lawyers on 2010 List 2Health News:Cleveland Attorneys Recognized as Ohio Super Lawyers on 2010 List 3Health News:"IPGDx, LLC Announces The Continued Validation Of Its Patented Technology For The Assessment Of Prognosis; PrognostiCheck" Getting the New Information to Patients and Do 2Health News:"IPGDx, LLC Announces The Continued Validation Of Its Patented Technology For The Assessment Of Prognosis; PrognostiCheck" Getting the New Information to Patients and Do 3Health News:Pay-for-performance programs may worsen medical disparities, study finds 2Health News:Pay-for-performance programs may worsen medical disparities, study finds 3Health News:Aspirin May Increase Risk of Crohn's Disease 2
(Date:8/20/2014)... Aug. 20, 2014 ApolloDx™ today announced it ... during a special event at the company,s office in ... September 5, 2014. The event, which will start at ... website, www.apollodx.com .    "We believe ... Jared Bauer , Co-Founder and Managing Partner of ...
(Date:8/20/2014)... , Aug. 20, 2014 Reportlinker.com announces ... its catalogue: Global Feminine Hygiene Products Industry ... report analyzes the worldwide markets for Feminine Hygiene Products ... Pads/Towels, Tampons, Panty liners, and Others. The report provides ... , Japan , ...
(Date:8/20/2014)... , Aug. 20, 2014  Glades Drugs, an independent ... is proud to announce its expansion into a new corporate ... will feature an 8,000-square-foot office space and state of the ... applications for 100 open positions for the new facility. ... Lantana Road will serve as the chain,s corporate headquarters and ...
Breaking Medicine Technology:Global Feminine Hygiene Products Industry 2Global Feminine Hygiene Products Industry 3Global Feminine Hygiene Products Industry 4Global Feminine Hygiene Products Industry 5Global Feminine Hygiene Products Industry 6Global Feminine Hygiene Products Industry 7Global Feminine Hygiene Products Industry 8Global Feminine Hygiene Products Industry 9Global Feminine Hygiene Products Industry 10Global Feminine Hygiene Products Industry 11Global Feminine Hygiene Products Industry 12Global Feminine Hygiene Products Industry 13Global Feminine Hygiene Products Industry 14Global Feminine Hygiene Products Industry 15Global Feminine Hygiene Products Industry 16Global Feminine Hygiene Products Industry 17Global Feminine Hygiene Products Industry 18Global Feminine Hygiene Products Industry 19Global Feminine Hygiene Products Industry 20Global Feminine Hygiene Products Industry 21Global Feminine Hygiene Products Industry 22Global Feminine Hygiene Products Industry 23Global Feminine Hygiene Products Industry 24Global Feminine Hygiene Products Industry 25Global Feminine Hygiene Products Industry 26Glades Drugs Moves to New Corporate Headquarters, 100 Open Positions 2
... Data from Serial Outpatient Infusion Study in Patients ... of Cardiology 56th Annual Scientific Session --, MOUNTAIN ... -- Scios Inc. announced today that an exploratory,920-patient, ... effect on the primary endpoint, a composite of ...
... March 26, 2007 /PRNewswire/ -- A large ... CYPHER(R) Sirolimus-eluting,Coronary Stent reported favorable safety and ... investigators at the of,Cardiology's 56th Annual Scientific ... a prospective, single-arm study designed,to evaluate the ...
Cached Medicine Technology:Scios Announces Results From Exploratory Nesiritide Study Providing,Important New Renal and Mortality Safety Data with a Neutral Effect,on the Primary Endpoint 2Scios Announces Results From Exploratory Nesiritide Study Providing,Important New Renal and Mortality Safety Data with a Neutral Effect,on the Primary Endpoint 3Scios Announces Results From Exploratory Nesiritide Study Providing,Important New Renal and Mortality Safety Data with a Neutral Effect,on the Primary Endpoint 4Scios Announces Results From Exploratory Nesiritide Study Providing,Important New Renal and Mortality Safety Data with a Neutral Effect,on the Primary Endpoint 5Scios Announces Results From Exploratory Nesiritide Study Providing,Important New Renal and Mortality Safety Data with a Neutral Effect,on the Primary Endpoint 6Scios Announces Results From Exploratory Nesiritide Study Providing,Important New Renal and Mortality Safety Data with a Neutral Effect,on the Primary Endpoint 7Two-Year Patient Registry Results Support Safety and Efficacy of,Cypher Sirolimus-Eluting Coronary Stent in 'Real World' Uses 2Two-Year Patient Registry Results Support Safety and Efficacy of,Cypher Sirolimus-Eluting Coronary Stent in 'Real World' Uses 3Two-Year Patient Registry Results Support Safety and Efficacy of,Cypher Sirolimus-Eluting Coronary Stent in 'Real World' Uses 4
... Laser System is a solid state Holmium: ... in all areas of the urinary tract, ... , ,A variety of reusable fibers provide ... clinical versatility and outcomes. Standard 115V electrical ...
... offers increased bone surface area contact between ... management of nonunions in long bones., ,Grid-Like ... of Contact on Host Bone , ,The ... cathode offers increased surface area and a ...
... proud to offer one of ... market at only 188 grams! ... a superior flow rate with ... mechanisms. The complementing electrodes provide ...
Flowmate makes portable uroflowmetry easy, accurate and dignified. Flowmate has automatic start and stop as well as simple and straightforward reporting from its own printer....
Medicine Products: