Navigation Links
Study Describes Molecules That Control Blood Pressure
Date:11/2/2007

n by stimulating production of WNK4, Ellison said. The extra WNK4 reduces the activity of WNK3. The entire complex of three WNK kinases also acts as a unit, modifying the activity of the NCC protein.

"What happens is that WNK4 normally inhibits WNK3, reducing salt resorption," Ellison said. "Mutant WNK4 blocks this effect, thereby generating more active WNK3, increasing salt transport and causing hypertension."

The WNK kinases are members of one of the largest protein families in the human body. There are 518 of them, coordinating a wide variety of biological functions. The WNK kinases, which were discovered in 2000, have been objects of research since a group led by Dr. Richard P. Lifton, who heads his own laboratory at Yale University, found a link between them and a rare inherited form of high blood pressure, called familial hyperkalemic hypertension.

Lifton had no immediate comment on the new report.

The new research is still at a basic level, Ellison said. "If we develop a new pharmaceutical approach to hypertension, that could be helpful," he added.

More information

A guide to lowering high blood pressure is offered by the U.S. National Heart, Lung, and Blood Institute.



SOURCES: David H. Ellison, M.D., professor, medicine, Oregon Health & Science University, Portland; Nov. 1, 2007, Journal of Clinical Investigation


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

0

GOOD

Page: 1 2

Related medicine news :

1. Rural Canadians travel far for specialists: study
2. A new study surpasses Gene Therapy Hurdle
3. Tomato Sauce reduces Cancer Risk- Study
4. A question on study of Adult Stem Cell
5. Study on obesity and heart failure
6. National Lung Study in the process
7. Marijuana gateway theory strengthened by study of twins
8. Old theory of adaptation confirmed by new study
9. Study casts doubt on keyboard ills
10. Gene study links endometriosis, infertility
11. Study reveals how stress can make you sick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... Myers, FL (PRWEB) May 23, 2013 On ... prediction in the midst of growing numbers of H7N9 cases ... UV-Aid, Predict H7N9 Bird Flu Cases Will Subside in Northern ... May 13th no new cases have been reported. , ... the flu is as predictable as flowers budding in the ...
(Date:5/23/2013)... 23 (HealthDay News) -- Schools should ensure that ... activity each day to support their health and ... report. Although previous studies show 60 ... health and development, it,s estimated that only about ... this recommendation, according to the report from the ...
(Date:5/23/2013)... (HealthDay News) -- A shortage of a critical tuberculosis ... the United States to contain the spread of the ... drug, isoniazid (INH), was first used in 1951 and ... core of any first-line treatment for tuberculosis (TB). Patients ... according to the U.S. Centers for Disease Control and ...
(Date:5/23/2013)... 2013 Special Learning, Inc., a ... resources for the autism, Down syndrome and special ... its first global autism treatment center and Special ... This new world-class program is the first of ... practices to treat and deliver exceptional education outcomes ...
(Date:5/23/2013)... May 23, 2013 Applied PilotFish ... today that it has added support for the Direct ... the eiConsole for Healthcare. In addition to the product’s ... LLP, FTP, and Web Services, it now offers support ... Protocol is a specification of the Direct Project ...
Breaking Medicine News(10 mins):Health News:UV Technologies Bold Prediction on H7N9 in China Comes True, New Cases End Without Aid of Flu Vaccine 2Health News:UV Technologies Bold Prediction on H7N9 in China Comes True, New Cases End Without Aid of Flu Vaccine 3Health News:U.S. School Kids Should Get Hour of Exercise Daily: Report 2Health News:Shortage of Key Drug Hampering U.S. Efforts to Control TB: Report 2Health News:Special Learning, Inc. to Expand its Services for Individuals with Special Needs with Opening of New Special Education School in the Philippines 2Health News:Special Learning, Inc. to Expand its Services for Individuals with Special Needs with Opening of New Special Education School in the Philippines 3Health News:PilotFish Expand’s Healthcare Integration Capabilities with Support for the New Direct Protocol in Its Latest Product Release 2
... health system echoes that of many caregivers , , MONDAY, ... to care for her gravely ill husband, journalist and ... moment. , More than a year ago, her husband, ... York City rehabilitation facility after spending several months there ...
... to California, The Beryl,Companies has begun providing post-discharge ... about patients, experiences within 72 hours,of an inpatient ... of this new service are BroMenn Healthcare System ... CA; HealthONE in Denver; Henry,Mayo Newhall Memorial Hospital ...
... HLTH ) announced today that it has commenced its ... stock at a price per share,of $8.80. The number of ... 43% of HLTH,s currently outstanding shares. The,last reported sales price ... Market on October 24, 2008 was $8.06 per share., ...
... Calif., Oct. 27 Accuray,Incorporated (Nasdaq: ARAY ), ... that its management is scheduled to present at the ... November,4, 2008 at 10:00 a.m. EST (7:00 a.m. PST.), ... available online from the,investor relations page of the Company,s ...
... Oct. 27 Authentidate,Holding Corp. (Nasdaq: ... workflow,management software and web-based services, today announced ... has implemented Authentidate,s,Inscrybe Healthcare service to more ... customer base in both Ohio and New ...
... no gastrointestinal, side effects for people who need the ... ... Oct. 27 Announced today at the American,Dietetic Association, ... both heme (protein-based iron) and non-heme,iron (plant-based iron) will ...
Cached Medicine News:Health News:Caring for Aging Loved Ones Can Be a Catch-22 2Health News:Caring for Aging Loved Ones Can Be a Catch-22 3Health News:Caring for Aging Loved Ones Can Be a Catch-22 4Health News:Caring for Aging Loved Ones Can Be a Catch-22 5Health News:The Beryl Companies Launches CARE Calls Program in Five Hospitals Across U.S. 2Health News:HLTH Corporation Announces Commencement of Its Tender Offer 2Health News:HLTH Corporation Announces Commencement of Its Tender Offer 3Health News:HLTH Corporation Announces Commencement of Its Tender Offer 4Health News:Accuray Incorporated to Speak at Oppenheimer Healthcare Conference 2Health News:WILLCARE Chooses Authentidate's Inscrybe(TM) Healthcare Service to Streamline Operations and Enhance Business Growth 2Health News:WILLCARE Chooses Authentidate's Inscrybe(TM) Healthcare Service to Streamline Operations and Enhance Business Growth 3Health News:WILLCARE Chooses Authentidate's Inscrybe(TM) Healthcare Service to Streamline Operations and Enhance Business Growth 4Health News:First-Ever Over-the-Counter Dual Action Iron Supplement Launched at the American Dietetic Association Conference in Chicago; Bifera to be Available in Select Stores in Early 2009 2
(Date:5/23/2013)... SAN DIEGO , May 23, 2013 /PRNewswire/ ... the prostate cancer treatment continuum was highlighted prominently ... the American Urological Association (AUA), in San Diego.  ... invasive high intensity focused ultrasound (HIFU) technology, the ... localize disease, and for urologists to consider minimally ...
(Date:5/23/2013)... May 23, 2013  Hologic, Inc. (Hologic or ... leading developer, manufacturer and supplier of premium diagnostics, ... emphasis on serving the healthcare needs of women, ... in a U.S. clinical practice comparing breast cancer ... with conventional 2D mammography alone showed a significant ...
(Date:5/23/2013)... ALBUQUERQUE, N.M. , May 23, 2013  Net ... in the telemedicine market, announced today the company has ... a telemedicine staffing company based in Huntsville, ... agency that specializes in the staffing and recruitment of ... upon completion of the final agreement, which is expected ...
Breaking Medicine Technology:Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 2Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 3Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 4Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 5Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 6First Large-Scale Population-Based Study in the U.S. Shows Hologic's 3D Mammography (Breast Tomosynthesis) Significantly Reduces Recall Rates While Simultaneously Improving Cancer Detection 2First Large-Scale Population-Based Study in the U.S. Shows Hologic's 3D Mammography (Breast Tomosynthesis) Significantly Reduces Recall Rates While Simultaneously Improving Cancer Detection 3First Large-Scale Population-Based Study in the U.S. Shows Hologic's 3D Mammography (Breast Tomosynthesis) Significantly Reduces Recall Rates While Simultaneously Improving Cancer Detection 4Net Medical Xpress Announces Acquisition of Telemedicine Staffing Company 2Net Medical Xpress Announces Acquisition of Telemedicine Staffing Company 3
... that a new market research report is available in ... Drugs, Markets and Companies ... concepts of pathomechanisms of pain as a basis for ... segments of the pain market are arthritis, neuropathic pain ...
... superDimension, Ltd. ® , a privately-owned company that develops ... received FDA 510(k) clearance for the superDimension marker delivery ... Company,s Electromagnetic Navigational Bronchoscopy (ENB) system, which has treated ... David S. Wilson, MD, Columbus Regional Hospital, ...
Cached Medicine Technology:Reportlinker Adds Pain Therapeutics - Drugs, Markets and Companies 2Reportlinker Adds Pain Therapeutics - Drugs, Markets and Companies 3superDimension Receives FDA 510(k) Clearance for Marker Delivery Kit 2superDimension Receives FDA 510(k) Clearance for Marker Delivery Kit 3superDimension Receives FDA 510(k) Clearance for Marker Delivery Kit 4
... technology has allowed for perfecting mini-invasive endoscopic ... various pathologies with a considerable social impact. ... reducing the post-operatory times and represents a ... in all hospital structures.,DEKAs family of Nd:YAG ...
... facial skin treatment, vascular treatment, ... Incorporates a wide range of ... hand pieces and large spot ... most flexibility. Compact table-top ...
... removal for all skin types, ... for leg and facial veins, ... a large spot sizes with ... treatment. An optional scanner ...
... 435 is a full system for hair removal, ... up a complete hair reduction system. The ... heating of the hair bulb and bugle. To ... distributed to the tissue through the MedArt® 413 ...
Medicine Products: