Navigation Links
Study Assesses Blood Thinner Use After Gastrointestinal Bleeding
Date:9/17/2012

MONDAY, Sept. 17 (HealthDay News) -- New research suggests that people who stop taking the blood thinner warfarin (Coumadin) because of gastrointestinal bleeding raise their risk of blood clots and death if they stay off the drug.

The study, published online Sept. 17 in the Archives of Internal Medicine, is limited because it looks only at what happened to patients over a 90-day period after suffering from gastrointestinal bleeding. But the findings do point to the risk of staying off the blood thinner for a long period, said Dr. Amir Jaffer, professor of medicine and division chief for hospital medicine at the University of Miami and co-author of a commentary accompanying the study.

In general, Jaffer said, he recommends that patients who suffer from bleeding in the gastrointestinal tract stop taking the blood thinner for about four days unless a significant reason exists to avoid the drug for the long term. "That number [of days] will vary depending on the severity of the bleeding," he said, adding that physicians should provide the proper guidance.

The blood thinner is prescribed to prevent conditions such as stroke and heart attack by making it harder for clots to form and block the blood stream. The medications, however, raise the risk of blood vessels rupturing. About 4.5 percent of patients treated with the blood thinner have an episode of gastrointestinal tract bleeding, according to the researchers.

The study authors reviewed medical records of nearly 450 Colorado patients who developed gastrointestinal bleeding while taking warfarin. The participants' average age was 72.

Close to 60 percent were taking warfarin again within two to nine days of bleeding. Over 90 days, about 12 percent of patients died. After researchers adjusted their statistics so they wouldn't be skewed by factors such as gender or age, they found that those who resumed taking warfarin were 31 percent less likely to die than those who didn't. Fewer than 6 percent of those who resumed warfarin died, compared to 20 percent of those who didn't.

Of the 260 patients who resumed taking warfarin, only one suffered from a stroke or major blood clot, compared to 5.5 percent of those who stayed off the drug.

In the commentary, Jaffer and his co-author said the findings might not apply to newer blood thinners, such as dabigatran and rivaroxaban, which could have a greater risk of gastrointestinal bleeding than warfarin over time.

More information

For more about blood thinners, visit the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCES: Amir Jaffer, M.D., associate professor, medicine, and division chief, hospital medicine, University of Miami Miller School of Medicine; Sept. 17, 2012, Archives of Internal Medicine


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. Study reveals how cancer drug causes diabetic-like state
3. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
4. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
5. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
6. No Added Cancer Risk From Hip Replacement Materials: Study
7. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
8. Early Study Finds Some Promise for Lung Cancer Vaccine
9. Narcissists Often Ace Job Interviews, Study Finds
10. Sexual objectification of female artists in music videos exists regardless of race, MU study finds
11. Soy may alleviate hot flashes in menopause, large-scale study finds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study Assesses Blood Thinner Use After Gastrointestinal Bleeding
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A Forever ... Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation ... as home to some of the world’s leading providers of cereal and other breakfast ...
(Date:6/25/2016)... ... 25, 2016 , ... Experts from the American Institutes for ... Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. , AIR ... care planning, healthcare costs and patient and family engagement. , AIR researchers will ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern ... Laude and his M.D from the David Geffen School of Medicine at UCLA. He ... Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events ... turn to unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. ... tools for healthy coping following a traumatic event. , Trauma sufferers tend to feel ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. ... accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, ... and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Research and Markets has announced ... Forecast to 2022" report to their offering. ... the patients with kidney failure, it replaces the function of ... patient,s blood and thus the treatment helps to keep the ... balance. Increasing number of ESRD patients & ...
(Date:6/23/2016)... , June 23, 2016 Research ... MEMS Devices Medical Market Analysis 2016 - Forecast to 2022" ... The report contains up to date financial data ... analysis. Assessment of major trends with potential impact on the ... analysis of market segmentation which comprises of sub markets, regional ...
(Date:6/23/2016)... and INDIANAPOLIS , June 23, ... a Lilly Diabetes Tomorrow,s Leaders Scholarship is any indication, ... winners, announced today online at www.diabetesscholars.org by ... 1 diabetes stand in the way of academic and ... the Foundation,s scholarship program since 2012, and continues to ...
Breaking Medicine Technology: