Navigation Links
Study Assesses Blood Thinner Use After Gastrointestinal Bleeding
Date:9/17/2012

MONDAY, Sept. 17 (HealthDay News) -- New research suggests that people who stop taking the blood thinner warfarin (Coumadin) because of gastrointestinal bleeding raise their risk of blood clots and death if they stay off the drug.

The study, published online Sept. 17 in the Archives of Internal Medicine, is limited because it looks only at what happened to patients over a 90-day period after suffering from gastrointestinal bleeding. But the findings do point to the risk of staying off the blood thinner for a long period, said Dr. Amir Jaffer, professor of medicine and division chief for hospital medicine at the University of Miami and co-author of a commentary accompanying the study.

In general, Jaffer said, he recommends that patients who suffer from bleeding in the gastrointestinal tract stop taking the blood thinner for about four days unless a significant reason exists to avoid the drug for the long term. "That number [of days] will vary depending on the severity of the bleeding," he said, adding that physicians should provide the proper guidance.

The blood thinner is prescribed to prevent conditions such as stroke and heart attack by making it harder for clots to form and block the blood stream. The medications, however, raise the risk of blood vessels rupturing. About 4.5 percent of patients treated with the blood thinner have an episode of gastrointestinal tract bleeding, according to the researchers.

The study authors reviewed medical records of nearly 450 Colorado patients who developed gastrointestinal bleeding while taking warfarin. The participants' average age was 72.

Close to 60 percent were taking warfarin again within two to nine days of bleeding. Over 90 days, about 12 percent of patients died. After researchers adjusted their statistics so they wouldn't be skewed by factors such as gender or age, they found that those who resumed taking warfarin were 31 percent less likely to die than those who didn't. Fewer than 6 percent of those who resumed warfarin died, compared to 20 percent of those who didn't.

Of the 260 patients who resumed taking warfarin, only one suffered from a stroke or major blood clot, compared to 5.5 percent of those who stayed off the drug.

In the commentary, Jaffer and his co-author said the findings might not apply to newer blood thinners, such as dabigatran and rivaroxaban, which could have a greater risk of gastrointestinal bleeding than warfarin over time.

More information

For more about blood thinners, visit the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCES: Amir Jaffer, M.D., associate professor, medicine, and division chief, hospital medicine, University of Miami Miller School of Medicine; Sept. 17, 2012, Archives of Internal Medicine


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. Study reveals how cancer drug causes diabetic-like state
3. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
4. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
5. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
6. No Added Cancer Risk From Hip Replacement Materials: Study
7. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
8. Early Study Finds Some Promise for Lung Cancer Vaccine
9. Narcissists Often Ace Job Interviews, Study Finds
10. Sexual objectification of female artists in music videos exists regardless of race, MU study finds
11. Soy may alleviate hot flashes in menopause, large-scale study finds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study Assesses Blood Thinner Use After Gastrointestinal Bleeding
(Date:12/9/2016)... ... December 09, 2016 , ... The ... Hotel in New York, NY, on December 3rd, to benefit Holy Name Medical ... the annual event, which raised over $1 million - the largest event in ...
(Date:12/9/2016)... ... 09, 2016 , ... "I had a terrible time trying to get my ... that if the nebulizer had a more child-friendly design, then children would be more ... the patent-pending NEBY to avoid the need to deliver medication via a nebulizer mask. ...
(Date:12/8/2016)... ... 2016 , ... The West Virginia Medical Institute (WVMI) announced ... name change aligns the entire company with its existing Quality Insights branded projects ... are very proud of the achievements associated with the West Virginia Medical Institute ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... (WCRI) officially opened registration today for its 33rd Annual Issues & Research ... . , The theme of the conference is “Persistent Challenges and New Opportunities: ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... that “Natural Language Processing–Enabled and Conventional Data Capture Methods for Input to Electronic ... Informatics . , Results of the comparative usability study demonstrate that a dictation-based ...
Breaking Medicine News(10 mins):
(Date:12/9/2016)... December 9, 2016 External ... Single-Chamber ICD, Dual-Chamber ICD, Cardiac Resynchronization Therapy Defibrillators ... Cardioverter Defibrillators The global defibrillators ... CAGR of 5.3% from 2016-2020 and CAGR of ... grow at a CAGR of 5.2% from 2016 ...
(Date:12/9/2016)... Research and Markets has announced the addition of the ... ... the global optical transceiver market to grow at a CAGR of ... the present scenario and the growth prospects of the global optical ... considers the revenue generated from the shipment of optical transceivers worldwide ...
(Date:12/9/2016)... 9, 2016 Mitsubishi Tanabe Pharma Corporation (Head ... Director, CEO: Dr. Masayuki Mitsuka ) has presented ... given edaravone intravenously in 10-14 day cycles for 48 ... the ALS Functional Rating Scale-Revised (ALSFRS-R). The data were ... ALS/MND in Dublin, Ireland . ...
Breaking Medicine Technology: