Navigation Links
Study: Trying to lose weight? Lose the fat substitutes
Date:6/22/2011

WEST LAFAYETTE, Ind. - Fat substitutes used in popular snack foods to help people control weight may have the opposite effect, according to Purdue University research.

"These substitutes are meant to mimic the taste of fat in foods that are normally high in fat while providing a lower number of calories, but they may end up confusing the body," said Susan E. Swithers, professor of psychological sciences. "We didn't study this in people, but we found that when rats consumed a fat substitute, learned signals that could help control food intake were disrupted, and the rats gained weight as a result.

"Substituting a part of the diet with a similar tasting item that has fewer or zero calories sounds like a common-sense approach to lose weight, but there are other physiological functions at work. Tastes normally alert the body to expect calories, and when those calories aren't present we believe the systems become ineffective and one of the body's mechanisms to control food intake can become ineffective."

The findings appear online in the current issue of Behavioral Neuroscience, which is published by the American Psychological Association. This research was funded by the National Institutes of Health. Swithers, as well as co-author Terry L. Davidson, a professor of psychological sciences, are members in Purdue's Ingestive Behavior Research Center. The study also was co-authored by undergraduate student Sean Ogden who graduated this spring.

In this study, laboratory rats received crushed potato chips as a supplement to their diet, and then were divided into two groups that were given either a low-fat chow diet or a high-fat chow diet.

These groups were each split into two smaller groups. One group on each diet was fed a mixture of high-fat chips and the fat-substitute chips, containing olestra, which is a synthetic fat with no calories, while the other group received only regular high-fat chips. The chips were provided for 28 days. Rats maintained on the high-fat chow diet gained more weight and developed more fatty tissue when they were given fat-substitute chips compared to the animals that ate only regular high-fat chips.

"Again we are looking at an animal model, but there are similarities for humans, and based on what we found, we believe that our findings question the effectiveness of using fat substitutes as part of a long-term weight loss strategy," Davidson said.

They also found when the group of rats that had previously consumed both fat substitute and high-fat chips were moved from a low-fat standard chow diet to a high-fat chow diet, they gained more weight.

"What's interesting here is that weight gain occurred regardless of when the rats consumed the low-calorie, fat-substituted chips," Swithers said. "The rationale behind providing both high-fat and olestra chips was to ensure that the animals received similar cues related to the sensory properties of fat, but with different consequences. Without this kind of control, we would not know how they were interpreting the chips as high fat or not."

In past studies, Swithers and Davidson have found that when rats consumed artificial sweeteners, they were more likely to overeat. They believe that a similar disruption of taste-calorie relations may be happening with both artificial sweeteners and fat substitutes.

"When the mouth tastes something sweet or fatty it tells the body to prepare for calories, and this information is key to the digestive process," Swithers said. "This is a reminder to not discount the roles that taste and experience with food play in the way the body's systems work together."


'/>"/>

Contact: Amy Patterson Neubert
apatterson@purdue.edu
765-494-9723
Purdue University
Source:Eurekalert  

Related medicine news :

1. UF study: When singing mice choose a mate, a skillful song gets the gal
2. Study: Stark differences in media use between minority and white youth
3. Study: What mom thinks matters when it comes to mental illness
4. Study: Children of divorce lag behind peers in math and social skills
5. Study: Most at-risk patients dont adhere to statin treatment, despite real benefits
6. Study: Surge in obesity correlates with increased automobile usage
7. Study: Lowering cost doesnt increase hearing aid purchases
8. Henry Ford Hospital study: Open-access colonoscopy is safe
9. Study: Cotton swabs prove problematic for ear health
10. Study: Resiniferatoxin may increase sepsis-related mortality
11. New study: Health reform to make health insurance affordable for nearly all families
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study: Trying to lose weight? Lose the fat substitutes
(Date:12/2/2016)... ... December 02, 2016 , ... Lori G. Cohen and ... will speak at the American Conference Institute’s 21st Drug & Medical Device Litigation ... Lead Sponsor of the conference. , Cohen, who chairs the firm’s Pharmaceutical, Medical Device ...
(Date:12/2/2016)... ... 2016 , ... More than 100 business, civic, community and ... the UNCF Dothan-Wiregrass Mayor’s Luncheon Dec. 9, 2016. This inaugural event, hosted by ... support to UNCF-member institutions, including Miles College, Oakwood University, Tuskegee University, Stillman College ...
(Date:12/2/2016)... ... 2016 , ... The annual time frame to change Medicare health and prescription ... December 7th. Currently-enrolled Medicare beneficiaries who are looking to switch from their current plan ... to make changes during this period order for their new policy to go into ...
(Date:12/2/2016)... ... December 02, 2016 , ... Dr. Raffi Hovsepian, ... included in the 2016 “Guide to America’s Top Plastic Surgeons” for seven consecutive ... of their education, experience, and professional associations. , One the most frequently ...
(Date:12/2/2016)... Hawaii (PRWEB) , ... December 02, 2016 , ... ... 2016 at the Hyatt Regency Waikiki Beach Resort and Spa in Honolulu, offering ... in the field of pain management. , The demand for supplemental training ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... in the ECG Cables And ECG Leadwires Market owing to ... devices. On the other hand, the Asia-Pacific ... rate during the forecast period. The market players ... plc ( Ireland ), Koninklijke Philips N.V. ( ... ( China ), held major share of the ...
(Date:12/2/2016)... 2016 Quantum Radiology,s Mobile Breast Center (QR ... directly to women at the workplace, thereby maximizing convenience ... Delta Air Lines and SunTrust Bank, and community health ... of wellness initiatives. "I think it,s a ... them to have a mammogram without taking a large ...
(Date:12/2/2016)... Dec. 2, 2016  Eli Lilly and Company (NYSE: ... for 2017 and provide updated financial guidance for 2016 ... a conference call on that day with the investment ... guidance. The conference call will begin at ... can access a live webcast of the conference call ...
Breaking Medicine Technology: