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Studies show LAM patients participate in clinical trials to help others, not themselves
Date:5/14/2009

CINCINNATITwo recent studies by researchers at the University of Cincinnati (UC) bring to light interesting findings about the diagnosis of the rare lung disease Lymphangioleiomyomatosis ( LAM) and the reasons LAM patients participate in research studies.

Brent Kinder, MD, Frank McCormack, MD, and Jared Hagaman, MD, working with colleagues in the division of pulmonary, critical care and sleep medicine at UC, found that patients with LAM were more likely to participate in clinical trials because of a shared cause and a feeling of altruism, as opposed to personal benefit.

In addition, this team found that CT scans given to young women who come to the emergency room for the first time with a collapsed lung are cost-effective and beneficial.

These findings will be presented at the American Thoracic Society International Conference in San Diego May 15-20.

LAM is a rare but serious lung disease that occurs when an unusual type of cell begins to grow out of control and spread to restricted areas in the body, including the lungs, kidneys, lymph nodes and vessels.

In the first study, 918 LAM patients in North America were surveyed to determine who participated in clinical trials and why. Of the 918 surveyed, 263 patients responded.

"Age, disease duration, use of oxygen therapy and disease presentation without chest pain were associated with trial participation, but the desire to help others with similar health problems was at the top of list," says Kinder, also director of the Interstitial Lung Disease Center at UC.

Results showed that 16 percent of LAM patient respondents participated in a clinical trial, but 85 percent of those people participated to help future patients.

In addition, results showed that the usual barriers to trial participation, like time constraints, risk of taking a placebo and geographic location, were found to be less important for LAM patients.

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Contact: Katie Pence
katie.pence@uc.edu
513-558-4561
University of Cincinnati Academic Health Center
Source:Eurekalert

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