Studies shed light on preserving fertility among cance...(lbertini Ph.D. University of Kansas Medi...),Health

Date:7/20/2009

lbertini, Ph.D., University of Kansas Medical Center, clinicians may be waiting too long three hours after thawing eggs to initiate fertilization with the sperm, a process necessary to create an embryo. When his research team used confocal microscopy to observe what was happening at a chromosomal level, they found that the structures needed to make the embryo's chromosomes align and divide were in place after only an hour. This indicates a shorter thawing time frame could have greater potential for success.

Restoring Fertility From the Bottom Up

Researchers at Stanford University, led by Renee A. Reijo Pera, Ph.D., have identified several genes involved in the formation of germ cells that give rise to eggs and sperm. These genes, DAZ and DAZL, form the basis of human embryo and germ cell growth and may be a key to understanding human reproductive failure one of the most common health problems in men and women and a common cause of birth defects. While continued progress in developing germ cells capable of making embryos renders fertility restoration feasible, it also raises significant ethical questions, says Dr. Reijo Pera.

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Contact: Clare Collins CollCX@upmc.edu 412-647-3555 University of Pittsburgh Schools of the Health Sciences Source:Eurekalert

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