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Studies provide insights into lung disease and lung function in young adults
Date:5/21/2008

he relationship between the lungs and blood vessels has been puzzling. For instance, air pollution, although it is breathed in through the lungs, has been shown to cause more heart disease than lung disease.

The study included 2,455 participants from CARDIA. Their levels of ICAM-1 during year 15 of the study were compared with their lung function in year 20. We found a fairly substantial decline in lung function in people with the highest levels of ICAM, compared with people with lower levels, regardless of their weight, Dr. Jacobs said. It suggests that lung function and endothelial health are related in some way. I think of endothelial dysfunction, oxidative stress and inflammation as evil triplets, feeding on each other.

More research is needed to better understand the relationship between the lungs and blood vessels, in order to help preserve better lung function throughout a persons life, he said.

Association of Circulating Adhesion Molecules with Lung Function: Results from the CARDIA Study (Abstract p. A753; Poster #H28)


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Contact: Keely Savoie
ksavoie@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

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