Navigation Links
Studies pinpoint specific brain areas and mechanisms associated with depression and anxiety
Date:11/11/2013

SAN DIEGO Research released today reveals new mechanisms and areas of the brain associated with anxiety and depression, presenting possible targets to understand and treat these debilitating mental illnesses. The findings were presented at Neuroscience 2013, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.

More than 350 million people worldwide suffer from clinical depression and between 5 and 25 percent of adults suffer from generalized anxiety, according to the World Health Organization. The resulting emotional and financial costs to people, families, and society are significant. Further, antidepressants are not always effective and often cause severe side effects.

Today's new findings show that:

  • A molecule in the immune system may contribute to depression, suggesting a potential biomarker for the disease (Georgia Hodes, PhD, abstract 542.1, see attached summary).
  • Decreasing a chemical signal in the amygdala, a brain area associated with emotional processing, produces antidepressant-like effects in mice (Yann Mineur, PhD, abstract 504, see attached summary).
  • MicroRNAs, tiny molecules that alter gene expression, correlate with how mice respond to socially stressful situations that cause depressive-like behavior. The findings may help determine why some people are more likely to suffer from depression than others (Karen Scott, PhD, abstract 731.2, see attached summary).

Other recent findings discussed show that:

  • A pathway between two brain regions, the amygdala and the hippocampus, plays a significant role in anxiety. Shutting down this connection can decrease anxiety-like behavior in mice (Ada Felix-Ortiz, MS, presentation 393.01, see attached speaker summary).
  • Aversive experiences can change how humans, particularly those with anxiety disorders, perceive stimuli. After a severe negative incident, patients with anxiety disorders over-generalize the experience and have increased emotional responses to subsequent similar situations (Rony Paz, PhD, presentation 295.05, see attached speaker summary).

"Today's findings represent our rapidly growing understanding of the individual molecules and brain circuits that may contribute to depression and anxiety," said press conference moderator Lisa Monteggia, PhD, of the University of Texas Southwestern Medical Center, an expert on mechanisms of antidepressant action. "These exciting discoveries represent the potential for significant changes in how we diagnose and treat these illnesses that touch millions."


'/>"/>

Contact: Kat Snodgrass
media@sfn.org
202-962-4090
Society for Neuroscience
Source:Eurekalert

Related medicine news :

1. Colorado Knee Specialist Robert LaPrade, MD Publishes New Studies Covering the Function of the Posterior Cruciate Ligament (PCL) and Treatments for PCL Injuries
2. The National Cancer Institute is Presenting “Acquisition of High Quality Tissues to Support Genome Studies” at Sample Prep East in Cambridge, MA, December 9-10, 2013
3. Studies of experimental hepatitis C drug show promise for preventing recurrence in liver transplant
4. Studies: Current hepatitis C treatments cant be used by more than half of patients; others lose opportunity for treatment
5. PolyU Advances Scientific Studies of Traditional Chinese Medicine
6. Rheumatoid arthritis and heart disease: Mayo Clinic studies shed light on dangerous connection
7. New Studies Linking Environmental Toxins to Infertility Validate Benefits of Fairhaven Health's FertileDetox
8. UCSB anthropologist studies the evolutionary benefit of human personality traits
9. For first time, drug developed based on zebrafish studies passes Phase I clinical trial
10. Sequencing studies help pinpoint gene in Prader-Willi syndrome
11. Birmingham Personal Injury Lawyers of Belt Law Firm, P.C., Discuss New Studies on Link between Strokes, TBI
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2017)... ... , ... American Farmer, will feature Chr. Hansen, Inc (CHR Hansen) in an ... 2017. American Farmer airs Tuesdays at 8:30aET on RFD-TV. Check your local listings for ... Denmark in 1874 after a groundbreaking discovery of how to industrialize enzymes. Rooted in ...
(Date:6/23/2017)... WV (PRWEB) , ... June 23, 2017 , ... ... protection services and personal financial planning to families and business owners in North ... Stones organization to help provide services to differently abled residents in the region. ...
(Date:6/22/2017)... ... 2017 , ... Groove Ring is excited to announce they've partnered with Olympic ... bands and all-purpose rings. Whether you’re an athlete, adventurer, professional, or love to venture ... , From the rock face to the auto shop, Groove Ring is the world's ...
(Date:6/22/2017)... ... June 22, 2017 , ... A June 12 article ... correspondent concerned about an apparent lack of oral hygiene by an aged parent who ... and dementia-related matters, suggests a number of steps, including scheduling a dentist visit. Northridge ...
(Date:6/20/2017)... ... June 20, 2017 , ... After months of negotiations, FaceCradle USA is proud to announce the ... June 21. , “Introducing our product on QVC is something we all worked hard to ... pillow to more than 90 million homes in the United States,” said FaceCradle USA President ...
Breaking Medicine News(10 mins):
(Date:6/5/2017)... Cincinnati location of Diplomat Specialty Infusion ... been awarded a Top Workplaces 2017 honor by ... on an employee survey administered by WorkplaceDynamics, LLC, a research ... measures several aspects of workplace culture, including alignment, execution, and ... ...
(Date:6/1/2017)... June 1, 2017 Nutriceutical Holdings (NH), parent ... Solutions (VRS), and KD Pharma Group have decided to ... by KD Pharma Group. KD Pharma Group will become ... to acquire the entire company. "We believe ... are committed to growing the NH companies by providing ...
(Date:5/29/2017)... -- Cellect Biotechnology Ltd. (NASDAQ: APOP ; TASE: APOP), ... selection of stem cells, today provided a corporate update ... March 31 st , 2017. "We ... quarter of 2017," said Dr. Shai Yarkoni, Chief Executive ... of the first blood cancer patient in the recently ...
Breaking Medicine Technology: