Navigation Links
Studies of patients with cirrhosis uncover limitations in liver cancer screening
Date:12/1/2011

Two studies available in the December issue of Hepatology, a journal of the American Association for the Study of Liver Diseases, have uncovered limitations in screening for primary liver cancer, also known as hepatocellular carcinoma (HCC). The first study found that, if given the choice during a clinical trial, most patients with cirrhosis prefer surveillance over the possibility of non-screening, therefore making a randomized study of HCC screening not feasible. A second study determined that ultrasonographic screening at three monthly versus six monthly intervals did not improve the detection of small liver cancers.

Medical evidence reports HCC to be the sixth most common cancer and the third most common cause of cancer death worldwide, with 90% of all cases in western countries attributed to chronic liver diseases, typically at the cirrhosis stage. The National Cancer Institute estimates that more than 26,000 cases and close to 20,000 deaths from liver and bile duct cancer occurred in the U.S. in 2011. Clinical guidelines recommend routine screening for HCC, but the efficacy and optimal intervals for testing are strongly debated by experts.

In the first study, researchers led by Professor Jacob George from the University of Sydney and Westmead Hospital in Australia, examined the feasibility of undertaking a randomized controlled trial of HCC surveillance in patients with cirrhosis. The screening program included ultrasonography every six months and alpha-fetoprotein testing every three months. Of the 205 participants with cirrhosis who received information outlining the risks and benefits of surveillance for liver cancer, 99.5% declined randomization, with 88% electing for a non-randomized screening program.

"While a randomized controlled trial is ideal to assess the success of a cancer surveillance program, we found that patients with cirrhosis declined randomization due to possible allocation to a non-screening group,
'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Surgeon studies with world-renowned oncoplastic pioneer
2. Studies explore new approaches to treating pain
3. New studies show progress, value in vaccination against deadly pneumonia
4. UH Rainbow Babies & Childrens Hospital begins studies on vitamin D to prevent heart disease
5. Studies Suggest Link Between Smog, Joint Disease
6. Gene therapy shows promise as hemophilia treatment in animal studies
7. MU studies link depression and breast cancer outcomes
8. CHEST 2011: Embargoed studies highlight new lung cancer and COPD research
9. European studies on risks of hepatocellular carcinoma
10. Trio of studies support use of PET/CT scans as prostate cancer staging tool
11. Hospital Programs to Reduce Antibiotic Resistance Working: Studies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/27/2014)... (PRWEB) November 28, 2014 Recently, iFitDress.com, ... added 100 new items to its assortment of ... big discounts, up to 70% off. Some models are ... beautiful discounted black cocktail dresses can enjoy a low ... always have something special for its clients. The business ...
(Date:11/27/2014)... 2014 Today, Digital-Signage-China.com adds 2 new items ... a digital signage media player promotion for Dec. 2014. ... a shopping wave in April, and this promotion will help ... find her desired models on our website, she/he can contact ... , The new models come in the latest designs, and ...
(Date:11/27/2014)... 28, 2014 This is a professional ... global Bronchoscopes industry with a focus on the Chinese ... status of the Bronchoscopes manufacturers and is a valuable ... interested in the industry. , Firstly, the report provides ... applications and manufacturing technology. Then, the report explores the ...
(Date:11/27/2014)... 28, 2014 Cyber Monday cannot come ... & Caicos. This boutique resort, ranked #1 out ... a few highly sought out openings before Christmas on ... are offering every seventh night complimentary if booked directly ... having a January 2015 promotion where every fourth night ...
(Date:11/27/2014)... St. Petersburg, Fl (PRWEB) November 28, 2014 ... , Beautiful Christmas boxes with bows on top, filled ... All prices are deeply discounted today while quantities last ... here . , All products are also available on Amazon ... are found on each Sublime shop product page for ease. ...
Breaking Medicine News(10 mins):Health News:Beautiful Black Cocktail Dresses Offered by Top Dress Supplier iFitDress.com 2Health News:Digital-Signage-China.com Offers Big Discounts On Its New Digital Signage Media Players 2Health News:Bronchoscopes Industry 2019 Forecasts for Global and China Region in New Research Report at ReportsnReports.com 2Health News:Bronchoscopes Industry 2019 Forecasts for Global and China Region in New Research Report at ReportsnReports.com 3Health News:The Tuscany on Grace Bay, Top-Rated TripAdvisor Resort in the Turks & Caicos Islands, Offers Special Pre-Christmas & January 2015 Promotions! 2Health News:Big Christmas Sales Begin Today at Sublime Beauty® for all Christmas Gift Selections and Skincare Sets 2
... A gene which is connected to Parkinson’s disease can ... revealed by the University of Colorado researchers, which has ... ,The results suggest the possibility for new drugs that ... further cell damage. Parkinson’s disease is a disorder that ...
... The secret of straight and curly hair lies four millimeters ... also trying to find the reason for the whitening of ... hair and straight, for straight hair. ,To get ... by Bruno Bernard, head of hair biology at L'Oreal, grew ...
... progress of twin babies, premature by 15 weeks through the ... 2 pounds at birth. // The Internet was chosen as ... and family informed with regard to the progress of the ... charity drive is also on to get additional funds for ...
... There appears to be a molecular link between the ... contains a high level of fat. // This is ... due to the high-fat diet, according to a recent ... gene encoding the enzyme GnT-4a glycosyltransferase (GnT-4a) disrupts insulin ...
... therapy research can be carried out in terminally ill ... are more than the risk involved in these patients, ... first cloned dolly sheep. Professor Wilmut is appointed as ... Edinburgh University. ,Professor Wilmut feels that stem ...
... done by Stephen Thom, MD, Ph.D., Professor of Emergency Medicine ... ,He said that a course of hyperbaric oxygen treatments ... body of the patient. ,Stem cells are progenitor ... the ability to differentiate into any type of cell. ...
Cached Medicine News:Health News:Gene Can Keep Brain Cells Alive 2
(Date:11/26/2014)... Scott Steiger lives in St. Louis ... the past 20 years, he,s traveled extensively and prior to that, ... six of the seven continents. Travel is a big part of ... - http://photos.prnewswire.com/prnh/20141126/161077 So when he designs ... of what,s required. His latest creation is the Road ...
(Date:11/26/2014)... 2014 Zynerba Pharmaceuticals , Inc., a ... transdermal synthetic cannabinoid treatments, today announced that the company ... Conference 2014. The conference will be held December 2 ... New York . Zynerba,s Chairman and CEO, ... on Tuesday, December 2. To listen to ...
(Date:11/26/2014)... The medical magnetic resonance imaging (MRI) ... with world market revenues for 2013 at $5.1 ... types of medical imaging have led to improvements ... conditions in children and adults, each imaging procedure ... Medical Imaging Markets , analyzes the current and ...
Breaking Medicine Technology:Steiger Has Created the First Pill Case Specifically Designed For Travel 2Zynerba Pharmaceuticals to Present at Piper Jaffray 26th Annual Healthcare Conference 2014 2Kalorama: Steady Growth in the Medical MRI Market 2Kalorama: Steady Growth in the Medical MRI Market 3
... - New Data from Phase III Intergroupe Francophone ... Mass., July 02, 2007 /PRNewswire-FirstCall/ --,Millennium Pharmaceuticals, Inc. ... comparative Phase III clinical trial evaluating a,VELCADE based ... induction therapy prior to stem cell transplantation,(SCT), the ...
... 2 July, 2007 -- Ablynx today announced ... study of its lead,development programme, ALX-0081, an ... targeting von Willebrand Factor (vWF), which can,reduce ... acute coronary,syndrome. , The Phase I study ...
Cached Medicine Technology:Velcade (bortezomib) for Injection Based Induction Therapy,Delivered High Post-Transplant Complete Remission Rate, a Critical,Marker for Increased Overall Survival 2Velcade (bortezomib) for Injection Based Induction Therapy,Delivered High Post-Transplant Complete Remission Rate, a Critical,Marker for Increased Overall Survival 3Velcade (bortezomib) for Injection Based Induction Therapy,Delivered High Post-Transplant Complete Remission Rate, a Critical,Marker for Increased Overall Survival 4Velcade (bortezomib) for Injection Based Induction Therapy,Delivered High Post-Transplant Complete Remission Rate, a Critical,Marker for Increased Overall Survival 5Velcade (bortezomib) for Injection Based Induction Therapy,Delivered High Post-Transplant Complete Remission Rate, a Critical,Marker for Increased Overall Survival 6Ablynx Announces Interim Results of First Nanobody Phase I Study of,ALX-0081 (ANTI-VWF) 2
The Erythrocyte Sedimentation Rate (ESR) can be used as a nonspecific search technique in case of suspicion of inflammatory reactions as well as for judgement of their development. VACUETTE® ESR...
Inquire...
VACUETTE paediatric tubes have decreased sample volumes and are ideal for small childrens' veins and geriatric patients....
Glucose tubes contain an anti-coagulant and a stabiliser. The tubes are ideal for glucose and lactate determinations....
Medicine Products: