Navigation Links
Studies in Mice May Offer Clues to Cleft Lip
Date:12/1/2011

THURSDAY, Dec. 1 (HealthDay News) -- The genetic repair of cleft lips in mice embryos could eventually lead to new ways to treat and prevent the birth defect in humans, U.S. researchers report.

The scientists pinpointed the role of genes for specific proteins that coordinate cellular signaling behaviors that play a major role in the development of cleft lip and palate. Working with specially engineered mice, they also reported that altering one type of molecule within a specific signaling pathway can correct cleft lip and palate.

The study was published recently in the journal Developmental Cell.

This is the first time that anyone has corrected this defect in embryos, according to study author Dr. Licia Selleri, an associate professor of cell and developmental biology at Weill Cornell Medical College in New York City.

"This is a very provocative result because it opens a completely new avenue of strategies for tissue repair," she said in a medical college news release.

While the findings hold promise, experts note that research involving animals frequently fails to lead to benefits for humans.

Children born with cleft lip and cleft palate, which are among the most common birth defects, often require multiple surgeries, speech therapy and orthodontics because of the disfigurement.

More information

The Nemours Foundation has more about cleft lip and palate.

-- Robert Preidt

SOURCE: Weill Cornell Medical College, news release, Nov. 28, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Studies of patients with cirrhosis uncover limitations in liver cancer screening
2. Surgeon studies with world-renowned oncoplastic pioneer
3. Studies explore new approaches to treating pain
4. New studies show progress, value in vaccination against deadly pneumonia
5. UH Rainbow Babies & Childrens Hospital begins studies on vitamin D to prevent heart disease
6. Studies Suggest Link Between Smog, Joint Disease
7. Gene therapy shows promise as hemophilia treatment in animal studies
8. MU studies link depression and breast cancer outcomes
9. CHEST 2011: Embargoed studies highlight new lung cancer and COPD research
10. European studies on risks of hepatocellular carcinoma
11. Trio of studies support use of PET/CT scans as prostate cancer staging tool
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Studies in Mice May Offer Clues to Cleft Lip
(Date:5/24/2015)... Scottsdale, Arizona (PRWEB) May 24, 2015 ... hired former Millennial Media strategy executive Jay Krihak ... as Medicx looks to ramp up its expertise ... services of the Pharmaceutical and Health sectors. , ... ad tech executive. Most recently, Krihak led sales ...
(Date:5/24/2015)... A report out just last ... best option for avoiding cardiovascular disease is exercise and ... the single most powerful predictor of death and survival, ... and family history of premature death -- a finding ... lung fitness. , The Importance of Cardiovascular Screening , ...
(Date:5/23/2015)... 2015 On May 13, Nithyananda Yoga ... youngster's yogic power learned through meditation and initiation at ... Bangalore, India. , Yogamaatha, a nine-year-old girl from North ... profile professionals attending the 2015 Business Advocacy Summit at ... blindfolded. , In a demonstration that lasted three ...
(Date:5/23/2015)... CA (PRWEB) May 23, 2015 With ... small businesses, are finding it increasingly difficult to provide ... which fail to provide adequate insurance for employees stand ... businesses been such an integral part of a business’s ... affordable healthcare for businesses, Online USA Doctors has created ...
(Date:5/23/2015)... Parker, CO (PRWEB) May 23, 2015 On ... participated in MuckFest. The event was a 5k mud obstacle ... affects more than 2 million people worldwide, and the reason ... our community,” said Chad Davis, owner of Farrell’s eXtreme Bodyshaping. ... National Multiple Sclerosis Society.” , The event was not only ...
Breaking Medicine News(10 mins):Health News:Medicx Media Solutions Expands Executive Team 2Health News:Recent Mayo Clinic Studies Help to Highlight the Value of Cardio Testing 2Health News:Recent Mayo Clinic Studies Help to Highlight the Value of Cardio Testing 3Health News:Nine-Year-Old Reads Blindfolded at Business Advocacy Summit 2Health News:Nine-Year-Old Reads Blindfolded at Business Advocacy Summit 3Health News:Online USA Doctors Now Offers Cost-Saving Alternative Healthcare for Businesses 2Health News:Online USA Doctors Now Offers Cost-Saving Alternative Healthcare for Businesses 3Health News:Farrell’s eXtreme Bodyshaping Team Runs through the Muck for MS 2
... associated with improvements in survival time for patients with ... a report in the March 22 issue of ... journals. David H. Howard, Ph.D., and colleagues at ... measure trends in life expectancy and lifetime medical costs ...
... March 2010 - Children who suffer physical or emotional abuse ... to new research published by Elsevier in Biological Psychiatry ... aging process begins at birth. Despite this, cellular aging ... that over time, the DNA within cells begins to show ...
... ... empowering users with the ability to inspire others simply by sharing their story. Users can ... or hear from others looking to provide inspiration with their story: http://www.eStoryShare.com ... (PRWEB) March 16, 2010 -- ...
... ... will improve your spring slumber. , ... Richmond, VA (PRWEB) March 16, 2010 -- After a long and, for many Americans, ... sleep advice web site says people hoping to improve the quality of their sleep ...
... "Asking if your dog is covered under your homeowners ... according to the Journal of American Medical Association, the number ... year," says Frank N. Darras , America,s top insurance ... now related to dog bites, equaling about $1 billion ...
... ... , ... ... ST. PAUL, Minn. , March 16 The Minnesota Coalition for Kids ...
Cached Medicine News:Health News:Childhood adversity may promote cellular aging 2Health News:New Social Media Site Launches Movement To Inspire The World! eStoryShare.com 2Health News:Five Spring Cleaning Sleep Tips from SleepBetter.org 2Health News:Five Spring Cleaning Sleep Tips from SleepBetter.org 3Health News:Is Your Dog Covered Under Your Homeowners Insurance? 2Health News:Is Your Dog Covered Under Your Homeowners Insurance? 3Health News:Is Your Dog Covered Under Your Homeowners Insurance? 4Health News:Is Your Dog Covered Under Your Homeowners Insurance? 5Health News:Minnesota Coalition for Kids Health Coverage Launches HealthyKidsMN.org 2Health News:Minnesota Coalition for Kids Health Coverage Launches HealthyKidsMN.org 3Health News:Minnesota Coalition for Kids Health Coverage Launches HealthyKidsMN.org 4Health News:Minnesota Coalition for Kids Health Coverage Launches HealthyKidsMN.org 5
(Date:5/22/2015)... , May 22, 2015  The Mesothelioma Victims ... victims of mesothelioma get the best possible compensation, ... individuals with this rare cancer caused by exposure ... up-to-date information related to treatment options such as ... call the Mesothelioma Victims Center anytime at 866-714-6466. ...
(Date:5/22/2015)... 2015 Research and Markets( http://www.researchandmarkets.com/research/28m7nx/guide_to_prepare ) ... to Prepare Application Dossiers for Oversea Medical device ... report to their offering. The ... market of the most growth potentiality, which is ... and producers to penetrate such market. It is ...
(Date:5/22/2015)... Research and Markets ( http://www.researchandmarkets.com/research/3rthk2/latest ... "Latest Regulations on Pharmaceutical International Multi-Center Clinical Trials ... This is first time in history, Chinese ... multi-center clinical trials of drugs in ... implemented on March 1, 2015. The guidance provides ...
Breaking Medicine Technology:Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 2Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 3Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 4Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 5China Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation 2China Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation 32015 Regulations on Pharmaceutical International Multi-Center Clinical Trials in China 2
... invasive alternative to ... total knee replacement, ... the availability of OrthoGlide Medial Knee Implant initial,clinical data., ... clinical study was presented on November 10th, 2007 at the,American ...
... Award-Winning Web Portal Provides Information about HIV and AIDS ... Project, a non-profit,organization working to change the course of ... women, received two prestigious business,awards for their Web portal. ... for Women in Business for Best Website of the ...
Cached Medicine Technology:Clinical Data Presented on OrthoGlide(R) Medial Knee Implant 2The Well Project Web Portal Receives Stevie(R) Website of the Year, InfoWorld 100 Award 2The Well Project Web Portal Receives Stevie(R) Website of the Year, InfoWorld 100 Award 3The Well Project Web Portal Receives Stevie(R) Website of the Year, InfoWorld 100 Award 4
... product, the Super Premium ALPHA 10 ... exceptional versatility in an intuitive and ... is the ideal system for Perinatology/Maternal ... offices, Surgical Applications, Breast Imaging, and ...
... Human Growth Hormone (hGH; somatotropin) is a 22 ... secreted by cells of the anterior pituitary. The ... best characterized of five members of a gene ... measure the expression of hGH released into the ...
... sulfate ester of DHEA, derived from sulfated ... in adrenal and extradrenal tissues. DHEA is ... adrenal cortex, and is a precursor for ... weak androgenic activity, which for unsulfated DHEA ...
... Dehydroepiandrosterone sulfate (DHEA-S) is the sulfate ester ... by enzymatic conversion of DHEA in adrenal ... C19 steroid secreted by the adrenal cortex, ... estrogen biosynthesis. DHEA possesses relatively weak androgenic ...
Medicine Products: