Navigation Links
Studies explore potential origins of addiction and treatments
Date:11/12/2013

SAN DIEGO Studies released today suggest promising new treatments for nicotine and heroin addiction, and further our understanding of pathological gambling and heroin abuse in those suffering chronic pain. This new knowledge, released at Neuroscience 2013, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health, may one day lead to non-pharmaceutical interventions and therapies to treat addiction.

According to the World Health Organization, 15.3 million people worldwide suffer from drug use disorders. A variety of brain areas and processes play a role in addictive behaviors, complicating treatment and costing millions of dollars and lives each year. Today's studies contribute to an understanding of how compulsive disorders like addiction develop and provide new insight into methods to treat addictive behaviors .

The new findings show that:

  • Magnetic stimulation of the brain helps some people decrease their smoking, and even quit altogether for up to six months after treatment (Abraham Zangen, abstract 635.03, see attached summary).

  • Stimulating an area of the brain associated with drug reward, the subthalamic nucleus, reduces rats' motivation to take heroin (Carrie Wade, PhD, abstract 818.03, see attached summary).

  • Chronic pain leads rats already exposed to drugs to take more and higher doses of heroin, suggesting that people with addiction are more susceptible to overdose when in chronic pain (Lucia Hipolito, PhD, abstract 158.05, see attached summary).

Other recent findings discussed show that:

  • Drug abuse stresses the brain, and the resulting dysregulation of systems involved in the stress response could contribute to negative feelings that trigger increased drug taking and addiction (George Koob, PhD, presentation 689, see attached speaker summary).

  • Research suggests an area of the brain known as the insula may be overactive in people with gambling problems. People with damage to this area were less prone to the motivations of gamblers, providing a clue to identify areas of the brain that are linked to gambling addiction (Luke Clark, PhD, presentation 686.05, see attached speaker summary).

  • Pathological gamblers may love a cash payout, but care less about other types of rewards, such as sex or food. Researchers found pathological gamblers showed decreased activity in reward-sensitive brain areas when money wasn't involved (Guillaume Sescousse, PhD, presentation 686.06, see attached speaker summary).

"Non-drug interventions would be an enormous step forward in drug abuse treatment, which currently relies on replacing one drug with another and has an extremely high rate of relapse," said press conference moderator Barry Everitt of the University of Cambridge, an expert in drug abuse research. "Today's exciting results give us new ways of understanding why compulsive conditions such as drug abuse and pathological gambling might arise, and give us targets to explore for non-drug treatment, which would help us treat a population suffering from addiction."


'/>"/>

Contact: Kat Snodgrass
media@sfn.org
202-962-4090
Society for Neuroscience
Source:Eurekalert

Related medicine news :

1. Studies pinpoint specific brain areas and mechanisms associated with depression and anxiety
2. Colorado Knee Specialist Robert LaPrade, MD Publishes New Studies Covering the Function of the Posterior Cruciate Ligament (PCL) and Treatments for PCL Injuries
3. The National Cancer Institute is Presenting “Acquisition of High Quality Tissues to Support Genome Studies” at Sample Prep East in Cambridge, MA, December 9-10, 2013
4. Studies of experimental hepatitis C drug show promise for preventing recurrence in liver transplant
5. Studies: Current hepatitis C treatments cant be used by more than half of patients; others lose opportunity for treatment
6. PolyU Advances Scientific Studies of Traditional Chinese Medicine
7. Rheumatoid arthritis and heart disease: Mayo Clinic studies shed light on dangerous connection
8. New Studies Linking Environmental Toxins to Infertility Validate Benefits of Fairhaven Health's FertileDetox
9. UCSB anthropologist studies the evolutionary benefit of human personality traits
10. For first time, drug developed based on zebrafish studies passes Phase I clinical trial
11. Sequencing studies help pinpoint gene in Prader-Willi syndrome
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... ... a crisis. Her son James, eight, was out of control. Prone to extreme mood shifts ... upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a knife ... and say he was going to kill them. If we were driving on the ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited ... To Recovery® program to drive cancer patients to and from their cancer treatments. ... highest quality of life and ongoing independence. Getting to and from medical treatments ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... Living, is proud to recognize Dr. Barry M. Weintraub as a prominent plastic ... most beautiful women in the world, and the most handsome men, look naturally ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) sponsors ... on June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, ... to helping service members that have been wounded in battle and their families. Venture ...
(Date:6/24/2016)... ... 24, 2016 , ... To succeed under value-based payments, healthcare ... unsure how to move forward, given the need to sustain current operations. PYA ... to an organization’s specific needs. , PYA Principal Martie Ross states, “Healthcare providers ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- Research and Markets has announced the addition ... - Forecast to 2022" report to their offering. ... to date financial data derived from varied research sources to ... potential impact on the market during the next five years, ... of sub markets, regional and country level analysis. The report ...
(Date:6/23/2016)... Research and Markets has announced the addition of ... their offering. The current ... environment for MedImmune to enter. The US ageing population creates ... drive considerable growth for effective anti-influenza medications. The introduction of ... but development is still in its infancy. ...
(Date:6/23/2016)... , , , WHEN: ... , , , , LOCATION: , , , Online, with ... , EXPERT PANELISTS:  , , , Frost & Sullivan,s Global Vice ... Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... industry is witnessing an exceptional era. Several new demand spaces, such ...
Breaking Medicine Technology: