Navigation Links
Studies explore potential origins of addiction and treaments
Date:11/12/2013

SAN DIEGO Studies released today suggest promising new treatments for nicotine and heroin addiction, and further our understanding of pathological gambling and heroin abuse in those suffering chronic pain. This new knowledge, released at Neuroscience 2013, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health, may one day lead to non-pharmaceutical interventions and therapies to treat addiction.

According to the World Health Organization, 15.3 million people worldwide suffer from drug use disorders. A variety of brain areas and processes play a role in addictive behaviors, complicating treatment and costing millions of dollars and lives each year. Today's studies contribute to an understanding of how compulsive disorders like addiction develop and provide new insight into methods to treat addictive behaviors .

The new findings show that:

  • Magnetic stimulation of the brain helps some people decrease their smoking, and even quit altogether for up to six months after treatment (Abraham Zangen, abstract 635.03, see attached summary).
  • Stimulating an area of the brain associated with drug reward, the subthalamic nucleus, reduces rats' motivation to take heroin (Carrie Wade, PhD, abstract 818.03, see attached summary).
  • Chronic pain leads rats already exposed to drugs to take more and higher doses of heroin, suggesting that people with addiction are more susceptible to overdose when in chronic pain (Lucia Hipolito, PhD, abstract 158.05, see attached summary).

Other recent findings discussed show that:

  • Drug abuse stresses the brain, and the resulting dysregulation of systems involved in the stress response could contribute to negative feelings that trigger increased drug taking and addiction (George Koob, PhD, presentation 689, see attached speaker summary).
  • Research suggests an area of the brain known as the insula may be overactive in people with gambling problems. People with damage to this area were less prone to the motivations of gamblers, providing a clue to identify areas of the brain that are linked to gambling addiction (Luke Clark, PhD, presentation 686.05, see attached speaker summary).
  • Pathological gamblers may love a cash payout, but care less about other types of rewards, such as sex or food. Researchers found pathological gamblers showed decreased activity in reward-sensitive brain areas when money wasn't involved (Guillaume Sescousse, PhD, presentation 686.06, see attached speaker summary).

"Non-drug interventions would be an enormous step forward in drug abuse treatment, which currently relies on replacing one drug with another and has an extremely high rate of relapse," said press conference moderator Barry Everitt of the University of Cambridge, an expert in drug abuse research. "Today's exciting results give us new ways of understanding why compulsive conditions such as drug abuse and pathological gambling might arise, and give us targets to explore for non-drug treatment, which would help us treat a population suffering from addiction."


'/>"/>

Contact: Kat Snodgrass
media@sfn.org
202-962-4090
Society for Neuroscience
Source:Eurekalert

Related medicine news :

1. Studies explore potential origins of addiction and treatments
2. Studies pinpoint specific brain areas and mechanisms associated with depression and anxiety
3. Colorado Knee Specialist Robert LaPrade, MD Publishes New Studies Covering the Function of the Posterior Cruciate Ligament (PCL) and Treatments for PCL Injuries
4. The National Cancer Institute is Presenting “Acquisition of High Quality Tissues to Support Genome Studies” at Sample Prep East in Cambridge, MA, December 9-10, 2013
5. Studies of experimental hepatitis C drug show promise for preventing recurrence in liver transplant
6. Studies: Current hepatitis C treatments cant be used by more than half of patients; others lose opportunity for treatment
7. PolyU Advances Scientific Studies of Traditional Chinese Medicine
8. Rheumatoid arthritis and heart disease: Mayo Clinic studies shed light on dangerous connection
9. New Studies Linking Environmental Toxins to Infertility Validate Benefits of Fairhaven Health's FertileDetox
10. UCSB anthropologist studies the evolutionary benefit of human personality traits
11. For first time, drug developed based on zebrafish studies passes Phase I clinical trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/13/2016)... Canada (PRWEB) , ... February 13, 2016 , ... In ... foot forward. They’ll groom themselves to perfection, go out of their way to be ... date – just take a look at any online dating profile. , A ...
(Date:2/12/2016)... DC (PRWEB) , ... February ... ... Siemens Foundation today announced a new initiative—the Siemens Foundation-PATH Ingenuity Fellowships—to develop ... The partnership will recruit top students from U.S. universities who will draw ...
(Date:2/12/2016)... ... , ... As a former television executive, owner Tal Rabinowitz knows how stressful ... decompress, Rabinowitz found herself drawn to a casual meditation class while working at NBC ... implementing a 20-minute-per-day meditation practice with her team. After her tenure at NBC, she ...
(Date:2/12/2016)... , ... February 12, 2016 , ... Every winter, someone ... This winter the West Penn Burn Center, part of the Allegheny Health ... to bring you the “Space Heaters Need Space” campaign. , “Space ...
(Date:2/12/2016)... ... , ... Erlanger Agency has announced a new partnership in its ongoing community ... on the fight against breast cancer, fundraising for a local woman named Carmen, who ... Carmen is a loving single mother of two boys who also serves as caregiver ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... , Ungarn, February 12, 2016 ... das sich auf den ungedeckten medizinischen Bedarf ... positive Ergebnisse seines klinischen Forschungsprogramms bekannt. Das ... beschäftigt, ergab Verbesserungen ihrer respiratorischen Funktionen und ... ltd , ein Medizintechnikunternehmen, das sich auf ...
(Date:2/11/2016)... , Feb. 11, 2016 ... Diagnostics in Personalized Medicine and Cancer Therapy. - ... High-Growth Diagnostic Testing Markets. - Key Diagnostic Testing ... - Molecular Diagnostics in Genetic Testing. - Molecular ... Markets. - Over-the-Counter Diagnostic Products World Markets. ...
(Date:2/11/2016)... Stem cells are primitive cells found in ... the capacity to differentiate into mature cell types Stem ... first mouse embryonic stem cells were derived from embryos ... the first culturing of embryonic stem cells from non-human ... until 2006 As a result of these discoveries, stem ...
Breaking Medicine Technology: