Navigation Links
Studies attribute recent increase in multiple myeloma survival to novel therapies
Date:11/1/2007

ter understand trends in survival over time. We wanted to understand if the new therapies available to these patients would translate directly into improved survival, said lead author Shaji Kumar, MD, of the Mayo Clinic.

The first analysis studied 387 patient records to compare disease relapses before and after December 31, 2000, based on the availability of thalidomide and subsequent clinical trials of bortezomib and lenalidomide. The second analysis was conducted over a 36-year period (1971-2006) with a larger group of 2,981 patients with newly diagnosed MM. These patients were divided by date of diagnosis (before or after January 1, 1997) to understand the significance of the novel advances in MM therapies.

Study results illustrated a dramatic improvement in survival among patients diagnosed in recent years, both from the time of diagnosis and from relapse after stem cell transplantation. Among the patients in the relapse group, the researchers noted a significant improvement in overall survival for patients relapsing after 2000, compared with those relapsing before 2000 (24 vs. 12 months). Patients relapsing before 2000 were less likely to receive a prompt transplant and more likely to have relapsed disease at the time of transplant and to have had more treatment regimens prior to transplant, compared with the group who relapsed after 2000, but the improvement seen in the recent times was independent of these differences.

In the larger group of newly diagnosed MM patients, diagnosis within the last decade translated into a 50 percent improvement in overall survival (45 vs. 30 months). Though the team divided the groups into six-year intervals to understand trends throughout the 36 years, they found no significant changes in survival until the most recent six-year period. When the team examined the relative impact of age and gender, they found that patients younger than 65 benefited the most from the recent improvements and that
'/>"/>

Contact: Laura Stark
lstark@hematology.org
202-552-4914
American Society of Hematology
Source:Eurekalert

0

GOOD

Page: 1 2 3 4

Related medicine news :

1. Studies On Hearing Loss Discovers New Causes
2. Broccoli Found to Block Cancer Progression In Both Animal and Human Studies
3. Studies Advocate Natural Form Of Vitamin E
4. Cure For Autism Could Be Established Through Hamster Studies
5. Despite More Studies Researchers Are Still Confound With ADHD
6. Studies Show Brain becomes Less Specialized With Age
7. ISB To Establish Research Chair On Real Estate And Urban Studies
8. Studies Show Combination Drugs As A Poor Substitute For Anti-Coagulants In Stroke
9. Further Studies Needed To Completely Understand About Ventricular Fibrillation
10. Studies Report Mammograms Unsafe
11. Six Indians Win Australian Studies Fellowships
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2013)... By Amy Norton HealthDay Reporter , , WEDNESDAY, ... wrestled with athlete,s foot knows there is something about ... have the first detailed "map" of the fungal groups ... feet are the hottest neighborhood. It,s no ... organisms, such as bacteria, viruses and fungi, both outside ...
(Date:5/22/2013)... May 22, 2013 Successful Therapy ... Patricia O’Laughlin Psychotherapy in the Silver Lake community ... all ages as progression to existing Parents and ... ages into parenting therapy has always been suggested, ... O’Laughlin Psychotherapy now specializes in all aspects of ...
(Date:5/22/2013)... According to a May 14, 2013 US News ... Breast Cancer Surgery,” modern medical technology has given women with ... in a whole new light. Since the new approach known ... breast cancer and mastectomies with greater hope for a ... of plastic surgery to oncology, women had little choice but ...
(Date:5/22/2013)... disparities from the University of Miami Miller School of ... teamed up to hold the second annual "Why We ... Medicine." The theme of this year,s conference will ... reduce these disparities. , Despite steady improvement in the ... groups continue to be more vulnerable to lapses in ...
(Date:5/22/2013)... Award Presented at the 2013 Annual ... here: http://bit.ly/13DkFfk , Merrill Corporation is pleased ... Product/Service of the Year” at the 7th M&A Advisor ... Hotel in Palm Beach, Florida. , Merrill DataSite ... solution that optimizes the due diligence process and ...
Breaking Medicine News(10 mins):Health News:Scientists Map the Fungi on Your Feet 2Health News:Scientists Map the Fungi on Your Feet 3Health News:Patricia O’Laughlin Psychotherapy of Los Angeles Now Seeing Adults, Teens and Young Children 2Health News:Breast Augmentation – New Option for Breast Cancer Surgeries 2Health News:Why We Can't Wait: Conference to Eliminate Health Disparities in Genomic Medicine 2Health News:Merrill DataSite New Press Release: Merrill DataSite® Virtual Data Room Honored as “Information Management Product/Service of the Year” 2Health News:Merrill DataSite New Press Release: Merrill DataSite® Virtual Data Room Honored as “Information Management Product/Service of the Year” 3
... submitted by Age Concern and London School of Hygiene and ... years are having an increased threat for disease due to ... that old age people are not spending the required amount ... eye care costs and are not undergoing the recommended 30 ...
... and doctors, and increases medical error risks, according to ... heating and cooling systems and by loud voices of ... short-term memory, according to the study by Johns Hopkins ... two-year research project, acoustics experts Ilene Busch-Vishniac and James ...
... that more lizard families than assumed till now are ... , The researchers, writing in the journal Nature ... like pain and swelling from lizard bites, which were ... of meat left between their teeth from their scavenging ...
... diabetes as a strong risk factor for sudden cardiac ... the disease.// ,The authors writing in the October ... prevalence of diabetes mellitus in industrialized countries is rapidly ... high risk for sudden cardiac death. ,The ...
... organisms, are exposed to ever-changing environments, oxidative stress, ... to defend themselves against all these insults, gain ... simply by ‘stealing’ genetic information from other better-adapted ... sex, known as horizontal gene transfer. ...
... A dengue fever vaccine full of promise is being tried ... of the GlaxoSmithKline vaccine //have been completed in the US ... be finished by the end of next year, Dr. Hans ... strong interest in making the vaccine available fast, given that ...
Cached Medicine News:Health News:More Lizards, Including Pets, Found Venomous 2Health News:Bacteria Evolve Armamentarium Against Antibiotics By ‘Stealing’ Gen 2
(Date:5/22/2013)... STEPh, Inc., a full service medical communications ... web site ( http://www.stephreports.com ) dedicated to ... STEPh Reports STEPh Reports are comprehensive critical ... STEPh Report assesses the competitive landscape by individual drug ... and specific key issues.  STEPh Reports are written by ...
(Date:5/22/2013)... Minn. , May 22, 2013 /PRNewswire/ ... the successful completion of its global Phase ... an internally developed program for the management ... proprietary formulation technology.  USL255 is specifically engineered ... fluctuations in topiramate blood levels observed with ...
(Date:5/22/2013)... 2013 MEDIFIRST SOLUTIONS, INC. (OTCQB: MFST) would ... some recent company developments. As Medifirst continues to expand ... with shareholders. Integrating social media into its investor relations ... will post updates on Twitter.  The Facebook homepage is ... Says CEO Bruce J. Schoengood ...
Breaking Medicine Technology:Scientific and Technical Evaluation of Pharmaceuticals, Inc. [STEPh, Inc.], Launches New Competitive Intelligence Web Site 2Upsher-Smith Successfully Completes Phase III Study Of USL255 (Extended-Release Topiramate) For Adjunctive Treatment Of Epilepsy In Patients With Refractory Partial-Onset Seizures 2Upsher-Smith Successfully Completes Phase III Study Of USL255 (Extended-Release Topiramate) For Adjunctive Treatment Of Epilepsy In Patients With Refractory Partial-Onset Seizures 3Upsher-Smith Successfully Completes Phase III Study Of USL255 (Extended-Release Topiramate) For Adjunctive Treatment Of Epilepsy In Patients With Refractory Partial-Onset Seizures 4Medifirst Solutions, Inc. Announces Update To Shareholders 2
... 60,000 young children end up in emergency rooms every ... caregivers were not looking. To remind parents and caregivers ... for Disease Control and Prevention (CDC) and the Consumer ... the PROTECT Initiative , today launched the ...
... Dec. 13 , 2011 Mirixa Corporation, the leader ... that Stacey Lelko has joined the company as Vice ... lead Mirixa,s national sales team and develop strategic partner ... Ms. Lelko most recently served as Vice President ...
Cached Medicine Technology:CDC and CHPA Educational Foundation Launch Up and Away and Out of Sight 2CDC and CHPA Educational Foundation Launch Up and Away and Out of Sight 3Mirixa Names New VP of Sales and Business Development 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: