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Studies Ignite Hope for Long-Acting Allergy Vaccines
Date:9/28/2008

ed maker of the Pollinex Quattro vaccine, reported that the U.S. Food and Drug Administration had placed a "hold" on its clinical studies while the agency reviewed a report of a rare adverse event. The company noted that a physician involved said the event was "possibly related" to the study drug. Last November, the company said it had met with the FDA, submitted information, and would continue to work with the agency to lift the hold.

Meanwhile, Creticos said a large, multi-center trial replicated findings of the Tolamba pilot study that his team led. Additional studies are continuing.

Dr. Thomas B. Casale, chief of the Division of Allergy and Immunology at Creighton University School of Medicine in Omaha, Neb., expects it will take another couple of years for these vaccines to become available, assuming, he added, that the next wave of clinical trials show that these approaches are safe and effective.

Until there are better treatments, people with ragweed allergy can minimize their exposure by keeping windows in their cars and homes closed to prevent pollen from drifting in, according to the American Academy of Allergy, Asthma & Immunology. And take a shower after spending time outdoors, because pollen can collect on your hair and skin.

More information

The Asthma and Allergy Foundation of America can tell you more about outdoor allergies.



SOURCES: Thomas B. Casale, M.D., professor of medicine, and chief, Division of Allergy and Immunology, Creighton University School of Medicine; Omaha, Neb.; William C. Howland III, M.D., allergist, and medical director, Lovelace Scientific Resources, Austin, Texas; Peter Creticos, M.D., clinical director, Johns Hopkins Asthma and Allergy Center, Baltimore; Asthma and Allergy Foundation of America, Washington, D.C.; American Academy of Allergy, Asthma &am
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