Navigation Links
Studies: Current hepatitis C treatments can't be used by more than half of patients; others lose opportunity for treatment
Date:10/31/2013

DETROIT More than half of chronic hepatitis C patients studied in a new research project led by Henry Ford Hospital were not treated for the potentially fatal disease, either because they couldn't withstand current therapies or because they, or their doctors, were waiting for new treatments.

In a second, related study, Henry Ford researchers found that while the disease is not yet curable, there is a significant "lost opportunity" for hepatitis C patients to achieve the current best result of treatment.

Both studies are being presented at the annual meeting of the American Association for the Study of Liver Diseases being held in Washington, DC, Nov. 1-5.

Stuart C. Gordon, M.D., director of the Hepatology section at Henry Ford, and lead author of the first study, said it was launched because of a lack of information about the subject.

"Limited data exist concerning the clinical disposition of U.S. patients with chronic hepatitis C infection, including the reasons for lack of antiviral treatment," Dr. Gordon says. "Our goal was to add to that data."

The team collected electronic health records from four large American health systems of patients with confirmed chronic hepatitis C, a viral infection that progressively scars the liver and eventually destroys the organ and its vital functions.

Of these 4,271 patients diagnosed with the infection and still alive through the end of 2011, the median age was 57; 57 percent were male; 29 percent were black and 97 percent were insured.

  • 543, or 12.7 percent, had previously achieved a sustained virologic response (SVR), meaning the hepatitis C virus was suppressed to the point that it could no longer be detected in their blood for six months after anti-viral treatment.
  • 110, or 2.6 percent, were currently on anti-viral therapy.
  • Of the remaining 3,618 patients, 12 percent had never been followed up within the health care system, despite clinical confirmation that they had chronic hepatitis C.
  • The majority, 55 percent, were not being treated, either because of "absolute contraindications" to current therapy meaning the risk of available treatment is too high or because either the patient or physician were waiting for newer therapies.
  • Another 12 percent of patients had chosen not to start treatment, despite a doctor's recommendation to do so.

"These results confirm that only a small proportion of chronic hepatitis C patients in American health care systems who were still being followed at the end of 2011 had achieved an SVR with available antiviral regimens," Dr. Gordon said. The second study sought to identify "lost opportunities" to treat hepatitis C patients and achieve SVR, now the closest thing to a "cure" for the disease.

"We looked at data regarding testing for chronic Hep C, patient referral, patient visits and the start of treatment," explains Kimberly Ann Brown, M.D., division head of Gastroenterology at Henry Ford Hospital and lead author of the study's findings.

"In addition," Dr. Brown says, "we considered patient age, race, gender, income, marital status, psychiatric diagnoses and the number of comorbidities, or co-existing diseases."

The findings showed that of the 458 patients identified with a positive hepatitis C antibody, only 117 received confirmatory testing, were referred to a specialist and presented to the office for a visit. Of the 117 patients who came for the specialty visit, only 21, or 17.9 percent, were felt to be appropriate treatment candidates.

"This data speaks to the significant "lost opportunity" we have, not only in identifying patients with hepatitis C in our community, but also in providing them with appropriate treatment options," says Dr. Brown.


'/>"/>

Contact: Dwight Angell
dwight.angell@hfhs.org
313-850-3471
Henry Ford Health System
Source:Eurekalert

Related medicine news :

1. Studies: Motor control development continues longer than previously believed
2. Victoria Staley, AMTC Aluma, Gets Lead Role in Switching Lanes Coming Out in 2014 and in Current Film Prisoners
3. PharmaPoint: Pediatric Respiratory Syncytial Virus (RSV) Prophylactics - Current and Future Players
4. 24th NAMS Annual Meeting highlights future opportunities, current controversies in menopause care
5. Big Pharma Dealmaking Activity Highlighted by CurrentPartnering in Comprehensive Report Published at MarketPublishers.com
6. Accelerated radiotherapy more efficient than current practice
7. TASTE trial challenge current practice of blood clot aspiration after heart attack
8. Transcranial direct current stimulation improves sleep in patients with post-polio syndrome
9. Dr Sam Speron Is Thrilled To Add A New Third Current Laser to The Park Ridge Medical Spa
10. Current, Former Government Officials to Discuss Exchange Implementation in Sept. 18 Virtual Conference
11. America’s Health Insurance Announces Plans to Become a Registered and Certified Agent in the Federal Health Insurance Marketplace Exchange- Currently in Training
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... 2016 , ... Pixel Film Studios Released ProSlice Levels, a Media Slicing Effect ... videos a whole new perspective by using the title layers in ProSlice Levels ... , ProSlice Levels contains over 30 Different presets to choose from. FCPX ...
(Date:6/25/2016)... ... 2016 , ... Austin residents seeking Mohs surgery services, can now turn to ... Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to ... fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... recover from injury. Recently, he has implemented orthobiologic procedures as a method for ... is one of the first doctors to perform the treatment. Orthobiologics are substances ...
(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort ... holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain ... Disease (SCD) is a disorder of the red blood cells, which can cause episodes ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, ... and the Road To Recovery® program to drive cancer patients to and from their ... to ensure the highest quality of life and ongoing independence. Getting to and ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016 According to a new ... Pen Needles, Safety Pen Needles), Needle Length (4mm, 5mm, ... Mode of Purchase (Retail, Non-Retail) - Trends & Global ... the market for the forecast period of 2016 to ... Billion by 2021 from USD 1.65 Billion in 2016, ...
(Date:6/24/2016)... Belgium , June 24, 2016 ... the appointment of Dr. Edward Futcher ... Non-Executive Director, effective June 23, 2016.Dr. Futcher was ... Nominations and Governance Committees.  As a non-executive member ... independent expertise and strategic counsel to VolitionRx in ...
(Date:6/23/2016)... 23, 2016  MedSource announced today that it ... software solution of choice.  This latest decision demonstrates ... to their clients by offering a state-of-the-art electronic ... establishes nowEDC as the EDC platform of choice ... clients.  "nowEDC has long been a preferred EDC ...
Breaking Medicine Technology: