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Student researchers seek to develop new therapies for cancer
Date:5/31/2012

olecules that provoke the cancer cells.

Undergraduate students Hannah Do and Peter Tran also will be working full time through the summer, with each being selected for a Summer Undergraduate Research Fellowship (SURF) awarded by the UH Office of Undergraduate Research. Do will be maintaining a drug library of novel molecules and then determine the role and effects of these molecules in contributing to the initiation and development of prostate cancer. Her goal is to isolate new therapeutic targets for treating advanced prostate cancer. The scale of her project is unique for the undergraduate level and will incorporate resources provided by the pharmaceutical companies GlaxoSmithKline and Roche.

Tran will be testing whether a specially modified version of a protein promotes the development of aggressive life-threatening prostate cancers. The project will be an extension of his current lab work and will set the foundation for potential future studies aimed at therapeutically targeting this unique protein variation. Tran's studies will be the first performed with the center's new advanced imaging system for in-depth monitoring of tumor growth and cancer progression, awarded by the Cancer Prevention and Research Institute of Texas.

In addition to these three students, who will be continuing their studies at UH this summer, another student became the first Ph.D. candidate of the 30 enrolled at the CNRCS to successfully defend her dissertation and graduate with her doctorate this spring. Eylem Aydogdu's devotion to human health issues compelled her to pursue a career in research that impacts the quality of life. Specifically, she focused her research on understanding the regulation of tiny genetic molecules in mammary stem-like cells and breast cancer. The goal of her research project was to identify the deviating regulatory mechanisms between cancerous and noncancerous stem cells in order to develop a treatment targeting cancer stem cells. S
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Contact: Lisa Merkl
lkmerkl@uh.edu
713-743-8192
University of Houston
Source:Eurekalert  

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