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Structure of enzyme unravelled providing basis for more accurate design of chemotherapeutic drugs
Date:11/15/2012

ick Higgins of the University of Alabama, states that, together with the previously published structure of topoisomerase II beta, "...these two structures provide key information that will be relevant to understanding how these closely related proteins perform different roles during cell growth and tissue development. The newly described structure could also provide the basis for the design of more selective drugs, with a lower risk of side effects."


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Contact: Meghan Jendrysik
M.Jendrysik@Elsevier.com
617-397-2845
Elsevier
Source:Eurekalert

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