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Stroke prevention surgery less effective than meds, lifestyle change
Date:10/26/2013

eight.

For the final analysis, the scientists followed the patients for at least two years after treatment. Some patients were followed for as long as four years.

"We were expecting that at some point the incidence of new strokes in those who had surgery would drop below that of those who did not, but that didn't happen," said Derdeyn, who was the neurointerventional principal investigator of the study. "This proves that medical therapy is better than surgery for these patients."

In August 2012, the early results of SAMMPRIS led the FDA to alter the criteria for using the "wingspan" stent tested in the trial.

"The new guidelines include restricting use of this stent to patients with at least a 70 percent blockage who already have had two previous strokes while on aggressive medical management," said Marc Chimowitz, MBChB, professor of neurology at the Medical University of South Carolina and neurological principal investigator of the study.

This small subset of high-risk stroke patients was not specifically assessed in the SAMMPRIS trial. But Chimowitz noted that the study did compare stenting with medical therapy in several other subsets and did not identify any that benefited more from stenting than medical therapy.


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Contact: Michael C. Purdy
purdym@wustl.edu
314-286-0122
Washington University School of Medicine
Source:Eurekalert

Page: 1 2 3 4

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