Navigation Links
Stroke Risk May Be Higher in HIV Patients

By Randy Dotinga
HealthDay Reporter

WEDNESDAY, Jan. 19 (HealthDay News) -- Stroke rates have increased among people with HIV in recent years while declining in the U.S. population at large, new research shows, raising the possibility that treatments for the AIDS-causing virus may put these patients at higher risk for cardiovascular trouble.

There's no direct proof linking the medications to the higher stroke rate, but previous research has suggested that HIV drugs can boost cholesterol and triglyceride levels, both of which contribute to stroke risk.

"Until we have a better idea what's happening, this is a call or reminder to clinicians to be cognizant of these risk factors for stroke in these HIV patients," said study author Dr. Bruce Ovbiagele, a neuroscience professor at the University of California, San Diego.

For their study, published online Jan. 19 in the journal Neurology, Ovbiagele and colleagues examined a database of hospitalizations for stroke from 1997, when a new generation of AIDS drugs was in its early days of use, through 2006.

They found that while overall hospitalizations for stroke fell by 7 percent, the number of stroke hospitalizations in HIV-infected people rose by 60 percent in 2006. (The researchers adjusted their numbers to account for factors such as age and gender.)

The researchers also looked at the two kinds of stroke -- ischemic (when a blood vessel is blocked) and hemorrhagic (when a blood vessel bursts). There was no change in the percentage of hemorrhagic stroke patients who were HIV-positive, but the rate went up from 0.08 percent to .18 percent -- more than doubling -- among HIV patients who had ischemic strokes.

The latter number suggests, but doesn't prove, that more HIV patients are suffering from blockages in their blood vessels. Some previous research has suggested that HIV patients have higher levels of heart attacks, which also occur when vessels clog up.

"We know that many of the drugs that are used for AIDS treatment have metabolic complications, which include the addition of belly fat and an increase in serum triglycerides," Ovbiagele said. Both increase the risk of heart problems.

It's possible that HIV patients are living longer and simply getting to the age at which strokes are more common among all people, said Ovbiagele, who was at the University of California at Los Angeles, when the research was conducted. But the study also found that HIV patients had strokes earlier, on average, than other people.

Overall, the risk that an HIV patient will have a stroke remains low. However, patients who are on AIDS drugs should be aware that stroke is "highly preventable," Ovbiagele said, and they should work with their doctors to keep their weight and cholesterol levels under control.

Dr. Alejandro A. Rabinstein, a professor of neurology at the Mayo Clinic in Rochester, Minn., said that even while the link between AIDS medications and stroke isn't proven, HIV patients should go on low-fat, low-sodium diets and be monitored for high blood pressure and other risk factors.

However, he said, strokes will remain rare among patients on HIV drugs. "The risk may be increased, but it is overall a small risk," he said.

More information

For more about AIDS, see the U.S. National Library of Medicine.

SOURCES: Bruce Ovbiagele, M.D., MSc, neuroscience professor, University of California at San Diego; Alejandro A. Rabinstein, M.D., professor, neurology, Mayo Clinic, Rochester, Minn.; Jan. 19, 2011, Neurology, online

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New Guidelines Released for Stroke Care
2. Falls as Serious for Elderly as Stroke, Heart Attack: Experts
3. Statins May Be Harmful After Stroke
4. Prozac May Speed Physical Rehabilitation After Stroke
5. Link between signaling molecules could point way to therapies for epilepsy, stroke, other diseases
6. Liver disease a possible predictor of stroke: Study
7. Roundup: 2010 Advances in Heart Disease and Stroke Care
8. Americas stroke belt partially fueled by fried fish
9. Too Much Fried Fish Might Help Make South the Stroke Belt
10. Top research highlighted in fight against heart disease and stroke
11. Health Risks Rise for Medicare Patients in Year After Stroke
Post Your Comments:
Related Image:
Stroke Risk May Be Higher in HIV Patients
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room ... Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. ... of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, ... the latter, setting the bar too high can result in disappointment, perhaps even self-loathing. ... toward their goal. , Research from reveals that behind the ...
(Date:6/24/2016)... ... ... in a crisis. Her son James, eight, was out of control. Prone to extreme mood ... something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a ... children and say he was going to kill them. If we were driving on ...
(Date:6/24/2016)... ... 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited to ... Recovery® program to drive cancer patients to and from their cancer treatments. Comfort ... quality of life and ongoing independence. Getting to and from medical treatments is ...
(Date:6/24/2016)... ... June 24, 2016 , ... The ... recognize Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s ... the world, and the most handsome men, look naturally attractive. Plastic surgery should ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Bracket , ... launch its next generation clinical outcomes platform, Bracket eCOA (SM) ... held on June 26 – 30, 2016 in ... first electronic Clinical Outcome Assessment product of its kind to ... #715. Bracket eCOA 6.0 is a flexible platform ...
(Date:6/23/2016)... BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), ... company,s second affiliate in Latin America . ... ... Colombia ... ...
(Date:6/23/2016)... 2016 The vast majority of dialysis patients ... Treatments are usually 3 times a week, with treatment ... travel time, equipment preparation and wait time.  This regimen ... for patients who are elderly and frail.  Many elderly ... rehabilitation centers for some duration of time. ...
Breaking Medicine Technology: