Navigation Links
Stroke Damage Is Less in Rats Given Opioids
Date:6/17/2009

Drugs induce a state of hibernation that improves recovery, study shows

WEDNESDAY, June 17 (HealthDay News) -- Hibernation induced by opioid drugs reduced brain damage and behavioral dysfunction in a study of rats that experienced an experimental stroke, researchers report.

"Studies in hibernating and active squirrels have shown that 'natural hibernation' has anti-ischemic effects," Cesar Borlongan, a neuroscientist at the University of South Florida Center for Aging and Brain Repair, said in a news release about the study. "We've shown that a drug that induces hibernation can achieve similar results."

Borlongan, along with colleagues at the U.S. National Institutes of Health, gave the rats a drug called [D-ala2,D-leU5] enkephalin (DADLE) -- which belongs to the same drug family as morphine and heroin -- and then induced a stroke in the rats by blocking cerebral artery blood flow.

After the stroke, the rats that received the drug did better on behavioral tests than rats that weren't given the drug before a stroke, the researchers found.

"DADLE prevented cell death processes and behavioral abnormalities," they wrote. "The observation that this substance, previously shown to induce hibernation, attenuated deficits inherent in cerebral ischemia provides a new pharmacological target for stroke therapy."

The study appears online in the journal BMC Biology.

More information

The National Stroke Association explains the effects of stroke.



-- Robert Preidt



SOURCE: BioMed Central, news release, June 16, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Psoriasis Raises Risk of Heart Attack, Stroke, Death
2. Mini-Stroke Can Mean Major One Within Hours
3. Sacred Heart Hospital Starts to Expose Students to Stroke Awareness at an Early Age
4. Minimally invasive stroke treatment produces better patient outcomes than surgical operation
5. Window for Stroke Treatment Opens Wider
6. Compression Stockings Offer Little Benefit After Stroke
7. Statins Can Help Prevent Second Stroke
8. Siemens Demonstrates Groundbreaking Approach to Stroke Diagnosis at ASNR 2009
9. Risk Factor for Stroke More Common Among Whites
10. Aspirin Lowers Stroke Risk in Peripheral Artery Disease
11. Seniors Often Misstate Stroke History
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Stroke Damage Is Less in Rats Given Opioids
(Date:9/20/2014)... 20, 2014 Plumbing construction services ... of 5, indicating a moderately favorable purchasing environment for ... reflects current and future pricing trends that will limit ... Other factors that negatively affect buyer power are a ... and the moderate switching costs. Buyers benefit, however, from ...
(Date:9/20/2014)... Final Cut Pro X Plugin developers ... Information theme for FCPX filmmakers. , “Fun, cool, and simple ... theme,” says Christina Austin, CEO of Pixel Film Studios. “It ... Information features easy to use controls that give the user ... the background color, color of each circle outline, the position ...
(Date:9/20/2014)... September 20, 2014 MarijuanaDoctors.com recently ... showing at the PAIN Week conference that was ... and Casino in Las Vegas from September 2nd ... attended PAIN Week in the hopes of educating ... viable and legitimate tool to treat chronic Pain, ...
(Date:9/19/2014)... DC) (PRWEB) September 19, 2014 “Copay ... inflate sales of brand drugs among patients with prescription ... according to a new report from the ... Inspector General (OIG). Federal anti-kickback laws prohibit suppliers from ... subsidized by the federal government. , The report highlights ...
(Date:9/19/2014)... FRIDAY, Sept. 19, 2014 (HealthDay News) -- As kids ... the targets of cyberbullies, according to a recent study. ... grades 5 through 8 found that verbal and physical ... patterns vary, bullying intervention and prevention strategies must address ... bullying among boys and girls, the researchers said. The ...
Breaking Medicine News(10 mins):Health News:Plumbing Construction Services Procurement Category Market Research Report from IBISWorld Has Been Updated 2Health News:Plumbing Construction Services Procurement Category Market Research Report from IBISWorld Has Been Updated 3Health News:Plumbing Construction Services Procurement Category Market Research Report from IBISWorld Has Been Updated 4Health News:Today Pixel Film Studios Announced the Release of the Information Theme for Final Cut Pro X 2Health News:MarijuanaDoctors.com Experiences Unprecedented Support and Growth at Pain Week 2014 2Health News:PCMA: New OIG Report Cites Drug Manufacturer“Copay Coupon” Use in Medicare Part D 2Health News: Cyberbullying Seems to Ramp Up in Middle School 2
... , , , FOSTER ... WHAT: Siperian, Inc., a leading industry provider of a multidomain master ... IBM Global Business Services and Boehringer Ingelheim have teamed up for an ... Most Valuable?" Hussain Mooraj, vice president, Healthcare ...
... HONG KONG, Sept. 16 /PRNewswire-Asia/ -- At ... September 10, reporters were informed that the,First World Conference ... Physicians) and the First World Endoscopy Technology Expo,will be ... Professor Zhang Yangde, the chief ...
... HBV genotypes as well as mutations in the core promoter, ... association with the clinical outcome of liver disease, however, this ... the HBV genotype distribution in certain region. So far, there ... country with a big population and a relatively high HBV ...
... , , MENLO PARK, ... label-free technology that accelerates the development of biotherapeutic and pharmaceutical ... and Read Immunogenicity Assay Kit for rapid detection of anti-drug ... new assay kit provides life science researchers with new levels ...
... , , , NEW YORK, ... has received Orphan-Drug designation from the U.S. Food and Drug Administration ... announced that it had reached an agreement with the FDA regarding ... 3 trial in relapsed/refractory multiple myeloma and that the study is ...
... study finds supervised exercise has better results , WEDNESDAY, ... than shockwave treatment for relieving chronic shoulder pain, according ... used to treat shoulder pain, even though a number ... investigate, Norwegian researchers studied 104 men and women, aged ...
Cached Medicine News:Health News:Siperian to Host Webinar With Panel of Pharmaceutical Experts 2Health News:Siperian to Host Webinar With Panel of Pharmaceutical Experts 3Health News:Siperian to Host Webinar With Panel of Pharmaceutical Experts 4Health News:Siperian to Host Webinar With Panel of Pharmaceutical Experts 5Health News:The First World Conference of Endoscopy Physicians will be Held December 18-20, 2009, in Hong Kong 2Health News:The First World Conference of Endoscopy Physicians will be Held December 18-20, 2009, in Hong Kong 3Health News:ForteBio Launches Dip and Read(TM) Immunogenicity Assay Kit for Rapid Detection of Anti-Drug Antibodies 2Health News:Keryx Biopharmaceuticals Receives Orphan-Drug Designation for KRX-0401 (Perifosine) for the Treatment of Multiple Myeloma 2Health News:Keryx Biopharmaceuticals Receives Orphan-Drug Designation for KRX-0401 (Perifosine) for the Treatment of Multiple Myeloma 3Health News:Keryx Biopharmaceuticals Receives Orphan-Drug Designation for KRX-0401 (Perifosine) for the Treatment of Multiple Myeloma 4Health News:Shockwave Treatment May Not Be Best for Shoulder Pain 2
(Date:9/19/2014)... N.J. , Sept. 19, 2014 Merck (NYSE: ... States and Canada , is teaming ... Desafiando La Diabetes: Logra Tus Metas , an educational program encouraging ... blood sugar -- a key treatment goal to help reduce the ... States are at a higher risk for developing type ...
(Date:9/19/2014)... , Sept. 19, 2014 Larry J. ... CVS ), will speak before the National Press Club ... discuss the company,s recent move to stop selling tobacco products ... the future of health. "Dramatic changes in our ... care providers and government," Merlo has said. "CVS Health has ...
(Date:9/19/2014)... 19, 2014  BioSpecifics Technologies Corp. (NASDAQ: BSTC ... marketed as XIAFLEX ® in the U.S. and XIAPEX ... Tom Wegman , will present a corporate overview at ... Industry Conference. The presentation will take place ... the Millennium Broadway Hotel in New York, NY ...
Breaking Medicine Technology:Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 2Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 3Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 4Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 5CVS Health CEO to Address National Press Club on Landmark Decision to Quit Tobacco, Leadership in Health Care Innovation 2CVS Health CEO to Address National Press Club on Landmark Decision to Quit Tobacco, Leadership in Health Care Innovation 3BioSpecifics Technologies Corp. to Present at the 21st Annual BioCentury NewsMakers in the Biotech Industry Conference 2
... 2011 The U.S. Food and Drug Administration today ... (locally advanced or metastatic), non-small cell lung cancers (NSCLC) ... (Logo: http://photos.prnewswire.com/prnh/20090824/FDALOGO ) Xalkori ... will help determine if a patient has the abnormal ...
... Inc., a pioneer in the area of digital PCR, is ... to evaluate the capabilities of digital PCR and see the ... will start on Monday, September 12 in Boston and finish ... The QuantaLife ddPCR System claims to be the world,s most ...
Cached Medicine Technology:FDA Approves Xalkori with Companion Diagnostic for a Type of Late-stage Lung Cancer 2FDA Approves Xalkori with Companion Diagnostic for a Type of Late-stage Lung Cancer 3FDA Approves Xalkori with Companion Diagnostic for a Type of Late-stage Lung Cancer 4QuantaLife™ Kicks Off Droplet Digital™ PCR Road Show 2
The NPT7 blood gas analyzer measures pH/blood gases and oximetry on 90 L sample volume with a two-step sampling procedure. Clinical tests compare NPT7 accuracy to that of benchtop analyzers. 30 sampl...
... is a fully automated, upgradeable platform ... gas analyzer along with a customer ... freedom to focus on patient care. ... that are essential to efficient blood ...
... Helmer Platelet Agitators feature ... with non-slip texture coating ... circulation for your platelets. ... to be used in ...
... agitators offer a wide range of storage ... drawer storage platform to agitate smoothly, eliminating ... down and squeak. Sturdy, one-piece perforated drawers ... circulation for your platelets., ,i.Series platelet agitators ...
Medicine Products: