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Strides Made in Lung Cancer Treatment
Date:1/13/2010

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  • Belgian scientists identified three groups of lung tumors based on how they grow and destroy other tissue. Each separate type of behavior correlated with a different prognosis. The researchers are still searching for underlying molecular features that explain the behavior differences, said Dr. David Carbone, the Harold L. Moses chair in cancer research and director of the Specialized Program of Research Excellence in Lung Cancer at Vanderbilt-Ingram Cancer Center.
  • Finally, a set of changes in microRNA expression could help determine which patients should be funneled towards conventional chemotherapy and which should receive other types of treatment, researchers from Arizona report. "MicroRNAs are small RNAS that control the expression of many genes," explained Jacks. "This set of three microRNAs correlated with resistance to therapy. This needs to be validated, but could be useful in diagnosing patients and applying relevant therapies."

    • More information

    The U.S. National Cancer Institute has more on lung cancer.



    SOURCES: Jay Brooks, chairman, hematology/oncology, Ochsner Health System, Baton Rouge, La.; Jan. 12, 2010, teleconference with Roy Herbst, M.D., Ph.D., chief, thoracic medical oncology, University of Texas M. D. Anderson Cancer Center; Tyler Jacks, Ph.D., AACR president and director, David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; Paul A. Bunn Jr., M.D., IASLC executive director and professor of medicine and James Dudley chair in cancer research, University of Colorado, Denver; David Carbone, M.D., Ph.D., Harold L. Moses chair in cancer research and director, Specialized Program of Research Excellence in Lung Cancer, Vanderbilt-Ingram Cancer Center; and Matthew Meyerson, M.D., Ph.D., professor of pathology, Harvard Medical School; study a
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