Navigation Links
Stress hormone impacts memory, learning in diabetic rodents
Date:2/17/2008

Diabetes is known to impair the cognitive health of people, but now scientists have identified one potential mechanism underlying these learning and memory problems. A new National Institutes of Health (NIH) study in diabetic rodents finds that increased levels of a stress hormone produced by the adrenal gland disrupt the healthy functioning of the hippocampus, the region of the brain responsible for learning and short-term memory. Moreover, when levels of the adrenal glucocorticoid hormone corticosterone (also known as cortisol in humans) are returned to normal, the hippocampus recovers its ability to build new cells and regains the plasticity needed to compensate for injury and disease and adjust to change.

The study appears in the Feb. 17, 2008, issue of Nature Neuroscience and was conducted by the National Institute on Aging (NIA), part of the NIH. NIAs Mark Mattson, Ph.D., and colleagues in the Institutes Intramural Research Program performed the study with Alexis M. Stranahan, a graduate student at Princeton University in New Jersey.

This research in animal models is intriguing, suggesting the possibility of novel approaches in preventing and treating cognitive impairment by maintaining normal levels of glucocorticoid, said Richard J. Hodes, M.D., NIA director. Further study will provide a better understanding of the often complex interplay between the nervous system, hormones and cognitive health.

Cortisol production is controlled by the hypothalamic-pituitary axis (HPA), a hormone-producing system involving the hypothalamus and pituitary gland in the brain and the adrenal gland located near the kidney. People with poorly controlled diabetes often have an overactive HPA axis and excessive cortisol produced by the adrenal gland. To study the interaction between elevated stress hormones and the hippocampal function, researchers tested the cognitive abilities and examined the brain tissue in animal models of rats with Type
'/>"/>

Contact: Peggy Vaughn
nianews3@mail.nih.gov
301-496-1752
NIH/National Institute on Aging
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New research shows how chronic stress worsens neurodegenerative disease course
2. Ability to cope with stress can increase good cholesterol in older white men, study finds
3. Handling Stress Properly Increases Good Cholesterol
4. New Alzheimers findings: High stress and genetic risk factor lead to increased memory decline
5. Stressed-Out Moms Carry Babies on the Right
6. New Asthma Guidelines Stress Disease Control
7. Latest DES Analysis Stresses Importance of Physicians Well-Trained in Implantation Technique and Patient Follow-Up
8. Study identifies key player in the bodys immune response to chronic stress
9. Environmental stress probed in cardiovascular disease, diabetes
10. Parents PTSD May Boost Stress in Offspring
11. New nurses report job stress, need for better management
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/13/2014)... Fadhits.com is popular among worldwide women. Its lace ... Recently, the company has announced its new selection of ... all these outfits are available at discounted prices (from ... supplier is now offering similar discounts for many other ... many other designs for sale, including flower girl dresses, ...
(Date:7/13/2014)... July 13, 2014 A decreased ability to ... impairment and Alzheimer,s disease, while examinations of the ... protein associated with Alzheimer,s, in the brain, according ... today at the Alzheimer,s Association International Conference 2014 ... the studies, the decreased ability to identify odors ...
(Date:7/13/2014)... A Xarelto lawsuit webpage has been ... consumers with the most current information regarding serious internal ... medication, as well as the growing number of ... country. The law firm is now offering free legal ... internal bleeding and related complications while using Xarelto, including:, ...
(Date:7/13/2014)... July 13, 2014 Hope Palliative & Hospice ... grief support group at the Tamarack Senior Living Community in ... at 10:30 A.M. on the 3rd Wednesdays of every month. ... at the Tamarack Community located at 55 S. Greeley St. ... individuals and there is no cost for the group. ...
(Date:7/13/2014)... Wa (PRWEB) July 13, 2014 According ... by Vkool.com, this is a comprehensive guide that features ... deal with KP (keratosis pilaris). This guide ... 1: What Is Keratosis Pilaris? ,     Chapter 2: ... I Know If I Have KP? ,     Chapter ...
Breaking Medicine News(10 mins):Health News:Fadhits.com Announces a Special Offer on Elegant Quinceanera Dresses 2Health News:Smell and eye tests show potential to detect Alzheimer's early 2Health News:Smell and eye tests show potential to detect Alzheimer's early 3Health News:Smell and eye tests show potential to detect Alzheimer's early 4Health News:Smell and eye tests show potential to detect Alzheimer's early 5Health News:Smell and eye tests show potential to detect Alzheimer's early 6Health News:Smell and eye tests show potential to detect Alzheimer's early 7Health News:Xeralto Lawsuit Page Launched By Wright & Schulte LLC To Provide Information On Potential For Xarelto Bleeding Side Effects, Growing Litigation 2Health News:Xeralto Lawsuit Page Launched By Wright & Schulte LLC To Provide Information On Potential For Xarelto Bleeding Side Effects, Growing Litigation 3Health News:Xeralto Lawsuit Page Launched By Wright & Schulte LLC To Provide Information On Potential For Xarelto Bleeding Side Effects, Growing Litigation 4Health News:Hope Hospice Announces Grief Support Group at the Tamarack Senior Living Community 2Health News:Living With KP Book Review Exposes Jennifer Richards' Keratosis Pilaris Guide – Vkool.com 2Health News:Living With KP Book Review Exposes Jennifer Richards' Keratosis Pilaris Guide – Vkool.com 3
... a statement by Joon Yun, Director, Palo Alto Institute:The world ... pandemic, a panic that has proved more widespread than the ... swine flu was well grounded. After all, the "Spanish ... between 20 and 40 million people, and it could happen ...
... Helps New Orleans School ... This week in New Orleans, Davis Vision, one ... retail stores, national dental insurer United Concordia Dental and ... partnering on a community-based project will help children in ...
... their business attire in exchange for a fun and casual ... money for United Cerebral Palsy (UCP) of Central Arizona,s programs ... theme is Camp Casual and the official Casual for a ... to hold their event on another date if preferred. ...
... amygdala, a neural center for emotion, , , MONDAY, May ... to have an enlarged amygdala, a brain area linked ... researchers report. , This brain abnormality appears to be ... with others, the team said. , "This study adds ...
... gap between wealthier, poorer children is shrinking, study finds, , , ... a new study is that more American children from low-income ... The bad news is that there,s still a wide disparity ... against diphtheria, tetanus and whooping cough (pertussis), via the combo ...
... Health Monitoring Systems (HMS) is a Pittsburgh-based company pioneering ... Community Health Surveillance. HMS is currently supporting state and ... the H1NI Flu (Swine Flu). HMS has been ... of H1N1 since the first cases in the United ...
Cached Medicine News:Health News:The Viral Spiral - How A Meme About the Virus May Be More Contagious Than the Virus Itself 2Health News:The Viral Spiral - How A Meme About the Virus May Be More Contagious Than the Virus Itself 3Health News:Davis Vision, Visionworks, United Concordia Dental and Louisiana State University School of Dentistry Partner with Hands on New Orleans 2Health News:Valley Businesses Shedding Their Suits to Go Casual for a Cause 2Health News:Brain Anatomy Could Point to Autism 2Health News:Brain Anatomy Could Point to Autism 3Health News:More Low-Income Kids Are Getting Vaccinated 2Health News:More Low-Income Kids Are Getting Vaccinated 3Health News:Pittsburgh Life Sciences Company Using Community Health Surveillance Platform to Track H1N1 Flu (Swine Flu) 2
(Date:7/11/2014)... July 11, 2014  Kindred Hospital Houston Northwest, ... the opening of its new outpatient wound healing ... to people with chronic, hard to heal wounds. ... lead to amputation, lower leg wounds related to ... closure, and traumatic injury wounds which are complex ...
(Date:7/11/2014)... 2014  Veran Medical Technologies, a U.S. ... positive, cost-effective final results for the initial ... SPiNPerc endobronchial percutaneous biopsy study results support ... biopsy when a traditional bronchoscopic method is ... positive financial outcomes when more can be ...
(Date:7/10/2014)... , July 10, 2014  The U.S. Department ... three-year grant to University Hospitals (UH) Case Medical Center ... new national model aimed at improving care for patients ... Care," the project will test a unique model developed ... with late-stage disease, significant comorbidities, or demonstrated need for ...
Breaking Medicine Technology:Kindred Hospital Houston Northwest, With Wound Care Specialists, Opens Outpatient Wound Healing And Hyperbaric Center 2Veran Medical Publishes Lung Cancer Patient Management Study 2University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 2University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 3University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 4
Inquire...
Inquire...
The Snap-In Snap-Out-II Tip Inserts offer a large variety of configurations....
The Optima III 45 cm line of laparoscopic hand instruments is ideal for operative laparoscopic/endoscopic procedures or when a longer instrument is needed....
Medicine Products: