Navigation Links
Stress hormone, depression trigger obesity in girls
Date:2/23/2010

Depression raises stress hormone levels in adolescent boys and girls but may lead to obesity only in girls, according to researchers. Early treatment of depression could help reduce stress and control obesity -- a major health issue.

"This is the first time cortisol reactivity has been identified as a mediator between depressed mood and obesity in girls," said Elizabeth J. Susman, the Jean Phillips Shibley professor of biobehavioral health at Penn State. "We really haven't seen this connection in kids before, but it tells us that there are biological risk factors that are similar for obesity and depression."

Cortisol, a hormone, regulates various metabolic functions in the body and is released as a reaction to stress. Researchers have long known that depression and cortisol are related to obesity, but they had not figured out the exact biological mechanism.

Although it is not clear why high cortisol reactions translate into obesity only for girls, scientists believe it may be due to physiological and behavioral differences -- estrogen release and stress eating in girls -- in the way the two genders cope with anxiety.

"The implications are to start treating depression early because we know that depression, cortisol and obesity are related in adults," said Susman.

If depression were to be treated earlier, she noted, it could help reduce the level of cortisol, and thereby help reduce obesity.

"We know stress is a critical factor in many mental and physical health problems," said Susman. "We are putting together the biology of stress, emotions and a clinical disorder to better understand a major public health problem."

Susman and her colleagues Lorah D. Dorn, professor of pediatrics, Cincinnati Children's Hospital Medical Center, and Samantha Dockray, postdoctoral fellow, University College London, used a child behavior checklist to assess 111 boys and girls ages 8 to 13 for symptoms of depression. Next they measured the children's obesity and the level of cortisol in their saliva before and after various stress tests.

"We had the children tell a story, make up a story, and do a mental arithmetic test," said Susman. "The children were also told that judges would evaluate the test results with those of other children."

Statistical analyses of the data suggest that depression is associated with spikes in cortisol levels for boys and girls after the stress tests, but higher cortisol reactions to stress are associated with obesity only in girls. The team reported its findings in a recent issue of the Journal of Adolescent Health.

"In these children, it was mainly the peak in cortisol that was related to obesity," Susman explained. "It was how they reacted to an immediate stress."


'/>"/>

Contact: Amitabh Avasthi
aem1@psu.edu
814-865-9481
Penn State
Source:Eurekalert

Related medicine news :

1. New research shows emotional impact of low sexual desire and associated distress
2. Tired of Snow, Sleet, and Stress? Join Deepak Chopra for a Week-Long Meditation Retreat this March in Florida's Warm Sunshine
3. Say “I Love You” From Head to Toe with a Gift That's Healthy and Soothes Away Stress this Valentine's Day
4. Early life stress may predict cardiovascular disease
5. Super Bowl Stress Can Spark Heart Attacks
6. Stress Hormone Could Be Key to Alcoholism
7. One Type A Trait May Actually Lower Work Stress
8. Stress, Anxiety Can Up Risk of Depression in Pregnancy
9. Brain Expert Announces Stress Eraser Contest
10. Stress -- From molecules to behavior
11. APA Offers Resources on Managing Traumatic Stress in Wake of Haiti Earthquake
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/26/2017)... ... April 26, 2017 , ... ... to announce the ATA 2017 President’s Awards recipients, comprised of organizations and ... healthcare delivery. , The ATA 2017 President’s Awards recognize individuals and ...
(Date:4/26/2017)... ... April 26, 2017 , ... Infertility ... in pelvic conditions and has helped many women become pregnant upon treating their ... of office-based and simple outpatient evaluations. We can provide the necessary information ...
(Date:4/26/2017)... ... April 26, 2017 , ... ... an agile ecosystem and domain expertise for sponsors and CROs to speed ... trial supply management (RTSM) software platform. Bioclinica AGILE RTSM provides ...
(Date:4/25/2017)... , ... April 25, 2017 ... ... in Newport Beach, California, committed to raising awareness for Duchenne muscular dystrophy, ... from its randomized CAP-1002 (cardiosphere-derived cells) Phase I/II HOPE clinical trial in ...
(Date:4/25/2017)... ... 2017 , ... Lake Park Dental is now accepting new patients with crooked ... FL. With the help of this highly-effective, yet convenient system, patients can straighten their ... and less pain. , Drs. Sarah Jockin, Nicole Morganti, Sara Spear and Elizabeth ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... , April 19, 2017  SARES•REGIS Group ... it is developing at Conejo Spectrum Business Park ... to Atara Biotherapeutics, Inc. , a biopharmaceutical ... and life-threatening diseases that have been underserved by ... T-cell therapies for cancer, autoimmune and infectious disease. ...
(Date:4/18/2017)... , April 18, 2017 Viverae ® , ... announce the integration of IBM ® Watson Campaign ... deliver targeted communications for a personalized experience. Through digital ... on their health in real time. The enhanced experience ... most to members, wherever they are in their journey ...
(Date:4/18/2017)... and BLOOMINGTON, Minn. ... (NASDAQ: IMMY ) ("Imprimis"), an ophthalmology-focused ... Lens ("Precision Lens"), today announced the signing of ... agreement, Precision Lens will deploy a dedicated sales ... geographies in the U.S., primarily focused in 13 ...
Breaking Medicine Technology: