Navigation Links
Stress and depression are associated with shorter survival in head and neck cancer patients
Date:4/28/2011

WASHINGTON, DC (April 28, 2011)Studies have shown that stress can affect the immune system and weaken the body's defense against infection and disease. In cancer patients this stress can also affect a tumor's ability to grow and spread. However, the biological mechanisms that underlie such associations are not well understood. Now, researchers at Fox Chase Cancer Center find that poor psychosocial functioning is associated with greater vascular endothelial growth factor (VEGF) expressiona signaling protein that not only stimulates tumor growth, but is also associated with shorter disease-free survival in head and neck cancer patients.

"There is research showing that high VEGF expression in other cancers, such as ovarian, is associated with psychosocial factors," says Carolyn Fang, Ph.D., Co-Leader of the Cancer Prevention and Control Program at Fox Chase, who will be presenting the study at the 32nd Annual Meeting & Scientific Sessions of the Society of Behavioral Medicine on Thursday, April 28th. "This information coupled with what we already know about VEGF promoting tumor aggressiveness and poorer prognosis in head and neck cancer patients, certainly gave us a reason to look at this biomarker."

VEGF not only plays a pivotal role in angiogenesis, but it is also regulated by stress hormones and key cytokinesa category of signaling molecules used extensively in intercellular communication.

In the current study, Fang and colleagues looked at 37 newly diagnosed, pre-surgical head and neck cancer patients, to see if psychosocial functioning, such as perceived stress and depressive factors, was associated with VEGF, a biological pathway relating to patient outcomes. The patients were predominantly male (70.3%), and approximately 57-years-old, with primary tumor sites of the oral cavity (65.9%), larynx (19.9%), and oropharynx (13.5%). Over 40% of them were classified as having early-stage disease.

Each patient was given a
'/>"/>

Contact: Frank Hoke
Franklin.Hoke@fccc.edu
215-728-2700
Fox Chase Cancer Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Some TV Fans Distressed Without Favorite Shows: Study
2. Pregnant and Stressed May Mean Offspring Who Misbehave
3. Repeated stress in pregnancy linked to childrens behavior
4. Teachers-based intervention provides stress resistance in war-exposed children
5. Older age memory loss tied to stress hormone receptor in brain
6. Elevated levels of sodium blunt response to stress, study shows
7. Girls in Some Sports Face Raised Risk of Stress Fractures: Study
8. Exercise may prevent stress on telomeres, a measure of cell health
9. Chronic stress of cancer causes accelerated telomere shortening
10. Does Stress Reduction Benefit Cancer Patients Health?
11. Pilot study examines stress, anxiety and needs of young women with a unique breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... ... 31, 2015 , ... Ticket Down is a reliable source for authentic tickets ... Grant Park. The festival will end on Sunday, August 2nd. , ... annual Lollapalooza. This unique and unbelievably popular festival attracts the best in entertainment ...
(Date:7/31/2015)... ... ... The 2nd annual Ride to Fight On will start and end near the ... to Fight On is a cycling fundraiser that benefits the West Cancer Center, a ... University of Tennessee Health Science Center. A health and wellness festival featuring food, music, ...
(Date:7/31/2015)... ... July 31, 2015 , ... ... Group, Inc. has re-branded their social media profiles to better connect with the ... consumers to communicate, find information, share insights and opinions. The Rally Insurance Group, ...
(Date:7/31/2015)... ... July 31, 2015 , ... According to the article published July 27 on My ... was contained and extinguished by the city’s fire department before it caused major damage throughout ... time of the fire, and it was a fire alarm system that tipped off fire ...
(Date:7/31/2015)... (PRWEB) , ... July 31, 2015 , ... ... educating both readers and potential patients alike on various plastic surgery procedures including, ... covered also include such popular dermatology procedures like Botox and fillers. , ...
Breaking Medicine News(10 mins):Health News:Cheap 2015 Lollapalooza Tickets: Ticket Down Slashes Ticket Prices on Lollapalooza Tickets at Grant Park in Chicago for Saturday, August 1st and Sunday, August 2nd 2Health News:West Cancer Center Announces 2nd Annual Ride to Fight On 2Health News:West Cancer Center Announces 2nd Annual Ride to Fight On 3Health News:Rally Insurance Group, Inc. Connects to Customers Through Re-branded Social Media Profiles 2Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 2Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 3Health News:Cosmetic Town: Now Providing Interactive And Vital Medical Knowledge 2
... ,The 18th Conference on Retroviruses and Opportunistic Infections ... Boston from February 27 through March 2. Day three ... selected presentations from scientists supported by the National Institute ... National Institutes of Health. iPrEx Update ...
... a critical period for addressing weight-related behaviors among ... Illinois at Chicago. Among young children, obesity has ... among black and Hispanic children. The UIC ... U.S. Department of Agriculture to integrate obesity-prevention strategies ...
... , TUESDAY, March 1 (HealthDay News) -- Older adults carefully ... before they decide whether to take them, finds a new ... risks, they aren,t that interested. Researchers interviewed 356 people ... take medication that would reduce the risk of a heart ...
... Reporter , TUESDAY, March 1 (HealthDay News) -- In ... medications can be beneficial, even in those who don,t ... study found that when people without high blood pressure ... heart failure, stroke, all-cause mortality and a combination of ...
... , TUESDAY, March 1 (HealthDay News) -- A new ... United States and elsewhere may be infected with human papillomavirus ... other tumors. The finding could help public health ... the study authors say. "The incidence of genital HPV ...
... March 1, 2011 A daylong vision expo will ... Houston (UH), offering information on rehabilitation and resources for ... productive lives. The Houston Area Insight Expo ... offering workshops, speakers, panel discussions, information and resources. Presented ...
Cached Medicine News:Health News:CROI -- Day 3: Selected highlights of NIH-supported research 2Health News:$1 million USDA grant aims to reduce obesity in preschoolers 2Health News:Seniors Concerned About Side Effects of Heart Drugs 2Health News:Blood Pressure Drugs May Help Heart Patients Without Hypertension 2Health News:Blood Pressure Drugs May Help Heart Patients Without Hypertension 3Health News:Half of U.S. Men Infected With HPV, Study Reveals 2Health News:Eye expo at UH offers resources to the visually impaired 2
(Date:7/31/2015)... July 31, 2015  Semler Scientific, Inc. (Nasdaq: ... services to healthcare insurers and physician groups, today reported ... 2015. "In the second quarter of ... revenue growth of 54%, quarter over quarter revenue growth ... installed base of FloChec® units of 18%," said Doug ...
(Date:7/31/2015)... 2015  Xencor, Inc. (NASDAQ: XNCR ), a ... treatment of autoimmune diseases, asthma and allergic diseases, and ... Hata to its board of directors. ... development is a tremendous asset to our board," said ... officer of Xencor. "Xencor faces a range of opportunities ...
(Date:7/31/2015)... HYDERABAD, India , July 31, 2015 /PRNewswire/ ... Billing and CRM solutions for video, data and cloud ... (PoC) with a leading pharma giant for Internet ... managing different IoT applications offered on subscription model. ... Pharma giant is striving for business ...
Breaking Medicine Technology:Semler Reports Second Quarter 2015 Financial Results 2Semler Reports Second Quarter 2015 Financial Results 3Semler Reports Second Quarter 2015 Financial Results 4Semler Reports Second Quarter 2015 Financial Results 5Semler Reports Second Quarter 2015 Financial Results 6Xencor Appoints Yujiro S. Hata to Board of Directors 2Xencor Appoints Yujiro S. Hata to Board of Directors 3Magnaquest Signs a POC With a Leading Pharma Giant in Europe to Manage Subscription Management and Billing for Internet of Things (IoT) 2
... CITY, Calif. and TORTONA, Italy, July 28, 2011 ... a global technology and engineering Company wholly-owned by Italy,s ... broad collaboration to develop and produce sustainable detergent alcohols ... includes development of second generation detergent alcohols from cellulosic ...
... Pa., July 28, 2011 McNeil Consumer ... for new dosing instructions lowering the maximum daily dose ... U.S. from 8 pills per day (4,000 mg) to ... designed to help encourage appropriate acetaminophen use and reduce ...
Cached Medicine Technology:Codexis and Chemtex to Collaborate on Sustainable Detergent Alcohols for the Household Products Market 2Codexis and Chemtex to Collaborate on Sustainable Detergent Alcohols for the Household Products Market 3Codexis and Chemtex to Collaborate on Sustainable Detergent Alcohols for the Household Products Market 4McNeil Consumer Healthcare Announces Plans for New Dosing Instructions for TYLENOL® Products 2McNeil Consumer Healthcare Announces Plans for New Dosing Instructions for TYLENOL® Products 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: