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Strains of antibiotic-resistant 'Staph' bacteria show seasonal preference; Children at higher risk in summer
Date:2/27/2013

Strains of potentially deadly, antibiotic-resistant Staphylococcus aureus bacteria show seasonal infection preferences, putting children at greater risk in summer and seniors at greater risk in winter, according to results of a new nationwide study led by a Johns Hopkins researcher.

It's unclear why these seasonal and age preferences for infection with methicillin-resistant Staph aureus (MRSA) occur, says Eili Klein, Ph.D., lead author on the study and a researcher at the Johns Hopkins Center for Advanced Modeling in the Social, Behavioral and Health Sciences.

But he says that increased use of antibiotics in the winter may be one of the reasons. The winter strain that infects seniors at a greater rate is generally acquired in the hospital and resistant to more antibiotics. On the other hand, the summer strain of MRSA, which is seen with growing frequency in children, is largely a community-transmitted strain that is resistant to fewer antibiotics.

"Overprescribing antibiotics is not harmless," Klein notes. "Inappropriate use of these drugs to treat influenza and other respiratory infections is driving resistance throughout the community, increasing the probability that children will contract untreatable infections."

In fact, the study found that while MRSA strains exhibit a seasonal pattern, overall MRSA infections have not decreased over the last five years, despite efforts to control their spread.

A report on the study, which used sophisticated statistical models to analyze national data for 2005-2009, appears today in the online issue of the American Journal of Epidemiology.

As the researchers report, hospitalizations from infections tied to MRSA doubled in the United States between 1999 and 2005. The ballooning infection numbers were propelled by MRSA acquired in community settings, not hospital or other health care settings, as had been the case prior to 1999.

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Contact: Mark Guidera
mguider1@jhmi.edu
410-502-9405
Johns Hopkins Medicine
Source:Eurekalert

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