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Stored Ovarian Tissue Needs Testing Before Re-Implantation
Date:4/24/2008

real-time polymerase chain reaction (PCR), a test that amplifies sections of DNA to detect molecular markers that would indicate the presence of cancer cells. The authors suggested that, as methods for detecting cancer cells are improving all the time, and ovarian tissue can be stored for more than 10 years, tests to detect residual disease should be carried out just before transplantation rather than at the time of collection. To do this, it is necessary to freeze smaller pieces of ovarian tissue separately for minimal residual disease investigation.

"The next step is to inform patients about the increasing success of ovarian tissue transplantation, to continue to improve the success of ovarian tissue transplantation, but also to call on fertility centers that store ovarian tissue to look for minimal residual disease and to start freezing tissue now for future investigation," Meirow said. "All of this holds true for testicular tissue, too, although we are not so advanced in successfully removing, storing and transplanting testicular tissue as we are with ovarian tissue."

More information

The American Cancer Society has more about ovarian cancer treatment.



-- Kevin McKeever



SOURCE: European Society for Human Reproduction and Embryology, news release, April 21, 2008


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