Navigation Links
Stored Donor Blood May Have Shorter Shelf Life Than Thought

TUESDAY, March 5 (HealthDay News) -- A small new study adds more evidence that red blood cells stored longer than three weeks begin to lose their ability to deliver oxygen-rich cells to the tissue where they're most needed.

Researchers from Johns Hopkins University in Baltimore found that red cells in blood stored for that long gradually lose the flexibility needed to squeeze through the smallest capillaries. They also found that this ability does not return when the blood is removed from storage and transfused into patients during or after surgery.

The study included 16 patients scheduled for spinal-fusion surgery, which typically requires blood transfusions. The average age of the blood given to the patients was more than three weeks.

The findings were published online Feb. 28 in the journal Anesthesia & Analgesia.

"There's more and more information telling us that the shelf life of blood may not be six weeks, which is what the blood banks consider standard," study leader Dr. Steven Frank, an associate professor of anesthesiology and critical care medicine at the Johns Hopkins University School of Medicine, said in a university news release.

"If I were having surgery tomorrow, I'd want the freshest blood they could find," he added.

Frank said he realizes that blood banks do not have enough fresh blood for everyone, and that shorter storage periods would lead to lower blood inventories. He said, however, that the current practice of transfusing blood stored for up to six weeks may need to be reconsidered.

Frank noted that a previous study published in the New England Journal of Medicine found that heart-surgery patients who received blood stored longer than three weeks were nearly twice as likely to die as those who received blood stored for just 10 days.

Currently, two large studies are under way in the United States and Canada to compare the safety of older and newer blood. The results are expected next year.

More information

The American Association for Clinical Chemistry has more about blood banking.

-- Robert Preidt

SOURCE: Johns Hopkins Medicine, news release, March 4, 2013

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. History of abandoned urban sites found stored in soil
2. Male fertility can be restored after cancer treatment, says Pitt team
3. Hearing Restored in Mice With Noise-Induced Deafness
4. Donor Kidney Re-Used in Second Patient After Failing in First
5. Donor aortic graft improves reconstruction after partial laryngectomy
6. Antibodies from rabbits reduce risks associated with unrelated donor stem cell transplantation
7. IL-10 from donor skin cells helps the body incorporate skin grafts
8. Obese donors increase risk of death for pediatric liver transplant recipients
9. Severely Obese Donors Raise Risks for Kids With Liver Transplant
10. Survival excellent following living donor liver transplantation for acute liver failure
11. Moffitt researchers say race affect likelihood of finding suitable stem cell donor
Post Your Comments:
Related Image:
Stored Donor Blood May Have Shorter Shelf Life Than Thought
(Date:11/27/2015)... ... 2015 , ... The moment you stop improving is the ... the needs of advisers and clients but going above and beyond to find ... service. However, there's always room for improvement, which is why the entire Consulting ...
(Date:11/27/2015)... ... 2015 , ... CBD College is proud to announce that on ... accreditation to its Diagnostic Medical Sonography program. CBD College is honored to join this ... colleges and universities in the state of California make the cut. CBD College is ...
(Date:11/27/2015)... ... 2015 , ... Dr. Thomas Dunlap and Dr. Patrick Coleman ... with Emergency Medicine at St., Joseph Health System’s Santa Rosa Memorial Hospital , ... in similar ways and require time-critical intervention to avoid large area heart damage and ...
(Date:11/27/2015)... ... ... Indosoft Inc., developer and distributor of the world-class Asterisk ... Term Support) into its Q-Suite 5.10 product line. , Making the change to ... of Asterisk that will receive not only security fixes, but feature and bug ...
(Date:11/26/2015)... ... 2015 , ... Inevitably when people think Thanksgiving, they also think Holiday sales ... Black Friday and Cyber Monday massage chair sales to receive the best ... low to find the best massage chair deals, they can see all of the ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... 2015 AAIPharma Services Corp./Cambridge Major Laboratories, ... least $15.8  Million to expand its laboratories and ... . The expansion will provide additional office space ... demands of the pharmaceutical and biotechnology markets. ... provide up to 40,000 square feet of expanded ...
(Date:11/25/2015)... , Nov. 25, 2015  ARKRAY USA ... continues to provide evidence demonstrating the accuracy of its ... Congress on Insulin Resistance, Diabetes and Cardiovascular Disease in ... both the Company,s GLUCOCARD ® 01 meter and ... accuracy requirements. The ability to accurately measure glucose levels ...
(Date:11/25/2015)... 25, 2015 Kitov Pharma ... KTOV), a biopharmaceutical company focused on the development of ... conditions, today announced the closing of its previously announced ... ADSs ), each representing 20 ordinary shares of the ... The ADSs and warrants were issued in a fixed ...
Breaking Medicine Technology: