Navigation Links
Stopping a receptor called 'nogo' boosts the synapses
Date:3/18/2008

ns that are extensions of the neuron and help cells talk to other cells. Mice with lots of the nogo receptor had a different mix of dendritic spines than normal mice. In the hippocampus, the mutant mice had fewer mushroom-shaped dendritic spines and more stubby and thin spines than the other mice. Scientists dont yet know the ramifications of the change, but they say its firm evidence that the nogo receptor has effects on the anatomic structure of the brain. Creation and removal of dendritic spines is an important form of brain rewiring.

The team attributes much of the effects of the nogo receptor to its ability to strongly bind to a growth factor known as FGF2 (fibroblast growth factor 2), which in the brain and other parts of the central nervous system nourishes neurons, allowing them to branch out and grow new sprouts. When the nogo receptor is present in abundance, it binds to FGF2 molecules, and as a result neurons no longer branch and sprout as they otherwise would.

Altogether, the findings show that the nogo receptor has a broad impact on processes in the brain that underlie learning and memory, said Giger.

Its known that changes in synaptic strength can lead to rewiring of the nervous system in such a way that we can compensate for mild to moderate injuries, said Giger, who is a scientist in the Center for Neural Development and Disease. Enhancing synaptic plasticity can partially counter the effects of an injury like stroke, or traumatic brain injury. Really, the process happens routinely in many stroke patients its what makes rehabilitation after stroke possible.

Much of the same type of rewiring also happens as a result of exercise. Scientists have shown that exercise improves the brains neuroplasticity, boosting the brains ability to sprout new structures and send crisp signals, which in turn helps people recover from injuries to the central nervous system. And recently, researchers at the Karolinska Institute in Stoc
'/>"/>

Contact: Tom Rickey
tom_rickey@urmc.rochester.edu
585-275-7954
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Fugitive cancer cells can be blocked by stopping blood cells that aid them
2. Physicians focus on stopping pain epidemic
3. First 90 Days After Stopping Plavix Most Dangerous
4. New Booklet Reveals 12 Proven Methods for Stopping MRSA from Infecting Your Feet and Your Familys Feet
5. New Sedona Stopping Diabetes Program
6. Common drug for stopping preterm labor may be harmful for babies
7. Hands2GO(R) Hand Sanitizer Offers Alcohol-Free Alternative to Stopping the Spread of Flu at School and Work
8. On 30th Anniversary, Angioplasty Celebrated as Modern Medical Breakthrough in Stopping Heart Attack
9. Stopping Tysabri May Worsen MS
10. Stopping Statins After Stroke Doubles Death Risk
11. Pain receptor in brain may be linked to learning and memory
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... This is a professional and in-depth ... industry with a focus on the Chinese market. The ... the Sterilizers manufacturers and is a valuable source of ... the industry. This report provides a basic overview of ... In this part, the report presents the company profile, ...
(Date:12/25/2014)... New York, New York (PRWEB) December 25, 2014 ... of the 2010 DePuy ASR hip recall ( http://www.consumerinjurylawyers.com/DePuy/ ... Liebhard LLP reports. According to an Order issued in ... November 20th, the Court will convene an open conference ... Federal Building and United States Courthouse in West Palm ...
(Date:12/25/2014)... CA (PRWEB) December 25, 2014 The short ... was created in honor of a true 9/11 hero, ... two film festivals including the 24 hours of Nuremberg International ... in Bangladesh. , Actress, screenwriter and director Luciana ... produce this film together with her husband, Gregory Graham ...
(Date:12/25/2014)... When head lice hits a home or ... to get rid of it while keeping it from taking ... now have the solution right in their neighborhood: Lice ... Troopers provides full spectrum head lice screening and treatment services ... Sunset, Key Biscayne, Brickell, Coconut Grove, Kendall, Pinecrest and South ...
(Date:12/25/2014)... -- Overeating is common during the holidays, but there are ... says. "Don,t arrive at a party hungry. It may ... be attending a party, but deprivation leads to hunger, and ... Westchester Hospital in Mount Kisco, N.Y., said in a hospital ... day and even to have a snack before attending a ...
Breaking Medicine News(10 mins):Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 2Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 3Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 2Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 3Health News:Coral Gables Florida Gets Ready to Be Lice-Free with Lice Troopers 2
... kills a type of brain tumor.// ,A strain of ... which is one of the deadliest forms of brain tumors. ... to modern medical or surgical procedures. ,Researchers of Yale ... viruses through a series of tests to find out the ...
... Researchers from Netherlands have found out that certain ordinary ... cardiac arrest. ,The new study, which was published ... drugs interfere with the electrical activity controlling heartbeats that ... ,These drugs are those that can prolong the duration ...
... report done by Swedish scientists its said that it is ... prostate cancer than to wait and see if the disease ... prostatectomy, is a common procedure. The researchers had conducted he ... prostate cancer benefits the patients more than watching and waiting ...
... first test that// uses DNA in blood to diagnose cystic fibrosis. ... can analyze DNA samples from the blood and detect genes that ... adults. The test can not only predict the advent of the ... are not having the disease but are the carriers of the ...
... Italian researchers says that how long women can stay fertile may ... says that when the women will enter their menopause may also ... had looked into the data collected from nearly 3000 postmenopausal women ... journal Human Reproduction. ,The results of the study show that ...
... diseases and recent study says that// cocaine abuse can lead ... on to find out the effect of substance abuse on ... to find out the effect of cocaine abuse on the ... coronary angiography, there was evidence of heart aneurysms. ,Aneurysm ...
Cached Medicine News:
(Date:12/24/2014)... 2014  Lockton Dunning Benefits, the ... the addition of Vice President Kim Foerster ... Pharmacy Consulting team, Excelsior Solutions. ... to the position.  Most recently, she worked as ... Specialty Pharmacy, where she has held various managerial ...
(Date:12/24/2014)... Dec. 23, 2014 In response to urgent requests ... Sierra Leone , Direct Relief delivered two ... for the treatment of local health workers who contract Ebola ... dedicated Ebola care center was constructed for foreign health care ... not available for local Sierra Leonean health workers. ...
(Date:12/22/2014)... N.J. , Dec. 22, 2014  CytoSorbents ... marketing its CytoSorb® blood purification technology to help ... patients in 28 countries worldwide, today announced the ... , MD, FACS, as its Senior Vice President ... Dr. Di Russo is ...
Breaking Medicine Technology:Kim Foerster Joins Lockton Companies 2First Ebola Treatment Unit for Local Health Workers Arrives in Sierra Leone 2CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 2CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 3CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 4CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 5
... 24, 2011 Christiana Care Health System,s Helen ... clinical trial to determine if Crestor® (Rosuvastatin), a cholesterol-lowering ... colon cancer surgery. (Logo: http://photos.prnewswire.com/prnh/20090407/DC95299LOGO ) ... Crestor can stop the growth of tumor cells by ...
... important role oncology practitioners and patient support groups play ... of radiation therapy technology to treat cancer, honored select ... on March 23, 2011 at the Ritz-Carlton in Phoenix. ... in which residents of Phoenix and the surrounding areas ...
Cached Medicine Technology:Christiana Care Health System Leads National Colorectal Cancer Clinical Trial 2Elekta-sponsored Ceremony Honors Arizona Cancer Heroes 2Elekta-sponsored Ceremony Honors Arizona Cancer Heroes 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: