Navigation Links
Stopping a deadly killer
Date:3/19/2008

PITTSBURGH, March 19 To develop new strategies to control tuberculosis (TB), a contagious disease that infects one-third of the worlds population and kills almost two million people every year, the University of Pittsburgh Center for Vaccine Research has received an $11.4 million grant from the Bill & Melinda Gates Foundation. The grant will enable Pitt researchers to use new imaging technologies to study TB to shorten and simplify its course of treatment, potentially improving survival and curtailing the global TB epidemic.

One of the most challenging issues in treating TB and stopping its spread is the length of time it takes to adequately stem the infection, said JoAnne Flynn, Ph.D., principal investigator of the grant and professor of microbiology and molecular genetics, University of Pittsburgh School of Medicine. Current drugs are available, but we dont fully understand how or why they work. TB treatment must be continued for at least six months to be effective, placing an undue burden on those who are infected often from the poorest and most disadvantaged countries.

According to Dr. Flynn, TB is difficult to control because the germs that cause the infection hide from the immune system in small tissue nodules called granulomas, enabling the infection to reactivate years, and even decades, later. Although for the most part TB is a curable disease, patients must adhere to treatment long after symptoms have faded. This proves challenging in many regions of the world where medication is not readily accessible. Indeed, an inadequate or incomplete course of treatment is the major factor that causes drug-resistant TB strains to develop. These strains are alarmingly high in many countries around the world.

Current medications for TB were developed more than three decades ago, said Dr. Flynn. To create significantly shorter and simplified approaches to treatment, we must improve our understanding of this disease and how curre
'/>"/>

Contact: Clare Collins
CollCX@upmc.edu
412-647-3555
University of Pittsburgh Schools of the Health Sciences
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Stopping Statins After Stroke Doubles Death Risk
2. Stopping Tysabri May Worsen MS
3. On 30th Anniversary, Angioplasty Celebrated as Modern Medical Breakthrough in Stopping Heart Attack
4. Hands2GO(R) Hand Sanitizer Offers Alcohol-Free Alternative to Stopping the Spread of Flu at School and Work
5. Common drug for stopping preterm labor may be harmful for babies
6. New Sedona Stopping Diabetes Program
7. New Booklet Reveals 12 Proven Methods for Stopping MRSA from Infecting Your Feet and Your Familys Feet
8. First 90 Days After Stopping Plavix Most Dangerous
9. Physicians focus on stopping pain epidemic
10. Fugitive cancer cells can be blocked by stopping blood cells that aid them
11. Stopping a receptor called nogo boosts the synapses
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... City, Florida (PRWEB) January 22, 2015 IsoComforter, ... cold therapy machine with patented IsoTube design to treat specific ... has introduced the most progressive and easy to use patented ... treat post-operative and sports related orthopedic and muscle injuries. ...
(Date:1/22/2015)... 22, 2015 Payday lending practices in ... and cause financial distress to the states that permit ... Howard University’s Center on Race and Wealth. , While ... activity, payday loans at the same time substantially depress ...
(Date:1/22/2015)... January 22, 2015 As interest in the ... care gains momentum worldwide, Rev. Eric J. Hall , ... Network (HCCN), will be the keynote speaker on January ... Israel’s public health system. , The conference, “Hope and Resilience: ...
(Date:1/22/2015)... has released a new blog post presenting a list of vehicles ... , Some types of vehicles cannot be covered under an ... post to see if their vehicle qualifies for auto insurance coverage. ... the cars that cannot be covered by a plan. Clients have ...
(Date:1/22/2015)... January 22, 2015 Step into a ... the Science Museum of Virginia. Wicked Plants, the Museum’s ... Plants unearths 75 poisonous, carnivorous and diabolical plants inside ... room to uncover the biochemical, physical and neurological processes ...
Breaking Medicine News(10 mins):Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2Health News:Howard University Spotlights the Economic Impact of Payday Lending in Southern States 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 3Health News:Some Vehicles Cannot Be Covered By An Auto Insurance Policy! 2Health News:Wicked Plants are taking over the Science Museum of Virginia 2
... HealthDay Reporter , WEDNESDAY, April 11 (HealthDay News) -- ... of the postoperative experience of four children who all carried ... to three of the patients, while a similar case came ... genetic cases, the common painkiller codeine can be lethal. The ...
... published article in the journal Nursing for Women,s Health ... her childbearing. The author asserts that contraception is a means ... care providers to ensure they are healthy prior to conceiving ... According to the Centers for Disease Control and Prevention ...
... Regular walking can help reduce fatigue in some pancreatic cancer ... white men and women aged 66 or 67 who underwent ... before they were discharged from the hospital. One group ... a walking or exercise routine. The other group was told ...
... By Steven Reinberg HealthDay Reporter , TUESDAY, April ... birth controls pills containing drospirenone -- a man-made version of ... risk of blood clots and will require new labels. ... will inform users that the pills -- which include products ...
... April 11, 2012. Anna M. Barrett, MD will represent ... American Academy of Neurology Conference at the Ernest N. ... April 28. Four abstracts will be presented ... of spatial neglect after right-brain stroke. Spatial neglect is ...
... that women are less likely than men to get at ... odds of developing metabolic syndrome a risky and increasingly ... name for a group of risk factors including high ... part of the body which occur together and increase ...
Cached Medicine News:Health News:Codeine After Surgery Could Endanger Certain Kids: Study 2Health News:Codeine After Surgery Could Endanger Certain Kids: Study 3Health News:Codeine After Surgery Could Endanger Certain Kids: Study 4Health News:Timing pregnancy an important health concern for women 2Health News:Short Walks May Ease Fatigue in Pancreatic Cancer Patients 2Health News:Certain Birth Control Pills May Carry Higher Blood Clot Risk: FDA 2Health News:NJ stroke researchers report advances in spatial neglect research at AAN Conference 2Health News:Study: Women not getting enough exercise; at risk of developing metabolic syndrome 2
(Date:1/23/2015)... 23, 2015 Gem Pharmaceuticals announced today that the ... into the Company,s Phase 2 clinical trial.  This open-label ... lead compound, GPX-150 (an investigational medication), in approximately 30 ... Logo - http://photos.prnewswire.com/prnh/20150123/170966LOGO ...
(Date:1/23/2015)... China , Jan. 23, 2015 Tianyin Pharmaceutical ... company that specializes in the development and sale of ... generics and active pharmaceutical ingredients (API) today announced the ... (JCM) API operation. 1. Following the September ...
(Date:1/22/2015)... , Jan. 22, 2015  BiOptix is pleased to ... as Vice President of Chemistry and Biochemistry. Scott joins the ... AstraZeneca Pharmaceuticals, and Amgen throughout the course of his ... "Scott is a nationally recognized thought leader ...
Breaking Medicine Technology:Gem Pharmaceuticals Announces Enrollment of Initial Patients in its Phase 2 Clinical Trial to Assess the Efficacy and Safety of GPX-150 in Sarcoma Patients 2TPI's JCM Updates on Import Registration for International Clients 2TPI's JCM Updates on Import Registration for International Clients 3TPI's JCM Updates on Import Registration for International Clients 4BiOptix Expands Leadership Team with the Appointment of Dr. Scott Klakamp as Vice President of Chemistry and Biochemistry 2
Inquire...
... performance, the SZX7 is designed for ease ... task, from routine preparations to advanced research. ... zoom ratios in its class as well ... accurate reproduction of the original specimen in ...
The Stereomicroscope Stemi 2000 meets your demands in two respects. On the one hand it offers the low-price advantage common with Greenough-type instruments, on the other hand it features superior pe...
6.3X Zoom Ratio - Boasting magnifications from 0.8X to 5X, the twin zooming objective optical system developed exclusively by Nikon provides a zoom ratio of 6.3:1. Clickstops at 1X intervals allow ob...
Medicine Products: