Navigation Links
Stop-Smoking Drug Chantix May Carry Heart Risks, FDA Warns

THURSDAY, Dec. 13 (HealthDay News) -- People who take the prescription quit-smoking drug Chantix may be at higher risk for cardiovascular problems, and doctors should weigh the risks of the drug against it benefits, the U.S. Food and Drug Administration said.

A major review of clinical trials that compared patients who took Chantix (varenicline) to patients who took a placebo found that those who took the drug had slightly higher rates of serious cardiovascular events such as nonfatal heart attack, nonfatal stroke and cardiovascular-related death, according to an FDA drug safety communication released Wednesday.

However, the increased risk among people taking Chantix was not statistically significant, which means that it is unclear whether their increased risk was due to the drug or due to chance, the agency added.

Chantix works by blocking the effects of nicotine on the brain. The FDA first alerted the public in June 2011 about the possible increased risk of cardiovascular problems associated with Chantix. The agency told Pfizer Inc., the maker of Chantix, to conduct the data review to learn more about possible heart risks associated with the drug.

The new findings are similar to those in a clinical trial described in the FDA's June 2011 drug safety communication about Chantix. The warnings and precaution section of the Chantix label has been updated to include the results of the recent review, the FDA said.

For now, doctors should consider the risks and benefits of Chantix before prescribing it for patients. The agency noted that smoking is a major risk factor for heart disease, Chantix is effective in helping people to stop smoking, and quitting smoking brings immediate and significant health benefits.

Patients taking Chantix should contact their doctor if they develop new or worsening symptoms of cardiovascular disease, such as chest pain, shortness of breath, calf pain when walking, or sudden onset of weakness, numbness or difficulty speaking, the FDA said.

The agency also said that patients with questions or concerns about Chantix should talk to their doctor.

More information

The American Cancer Society offers a guide to quitting smoking.

-- Robert Preidt

SOURCE: U.S. Food and Drug Administration, news release, Dec. 12, 2012

Copyright©2012 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Herceptin May Carry Higher Heart Risks for Women Than Thought
2. African Chimps Carry Drug-Resistant, Human-Linked Staph
3. Some Schools Dont Let Kids Carry Asthma Inhalers
4. People Carrying Guns May Appear Bigger Than They Are
5. Certain Birth Control Pills May Carry Higher Blood Clot Risk: FDA
6. U.S. Lifestyles Thwarting Heart Health Progress: Report
7. Fainting in Healthy People May Be First Sign of Heart Trouble
8. Massage and the Aboriginal Didgeridoo - A Transcendental Healing Experience in the Heart of New York City
9. Even Light Smoking Boosts Womens Risk of Sudden Heart Death: Study
10. Common Heart Drug Might Dampen Some Autism Symptoms
11. A Single Pill for Heart Disease Prevention? from the December 2012 Harvard Women's Health Watch
Post Your Comments:
(Date:10/13/2017)... ... 2017 , ... Many families have long-term insurance that covers care for a ... waiver for care if the client has a cognitive impairment diagnosis. , “What ... is often waived, so the benefits from their insurance start immediately,” said Mechell Vieira, ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a ... has been awarded a contract by the Center for Medicare and Medicaid Services ... accelerate the enterprise use of Agile methodologies in a consistent and high value ...
(Date:10/12/2017)... Del. (PRWEB) , ... October 12, 2017 , ... ... and advisory services for healthcare compliance program management, will showcase a range of ... National Association for Assisted Living (NCAL) Convention and Expo to be held October ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has developed a ... and regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been ... standard. , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... Sept. 25, 2017  EpiVax, Inc., a leader ... and immune-engineering today announced the launch of EpiVax ... of personalized therapeutic cancer vaccines. EpiVax has provided ... access to enabling technologies to the new precision ... lead EpiVax Oncology as Chief Executive Officer. Gad ...
(Date:9/19/2017)... Mich. , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device company ... destruction of targeted tissues, announced three leadership team developments today:   ... PhD ... ... Veteran medical device executive Josh ...
(Date:9/13/2017)... --  OrthoAtlanta has been named the official orthopedic and ... for the 2018 College Football Playoff (CFP) National Championship to ... in Atlanta, Georgia . OrthoAtlanta is proud ... participating in many activities leading up to, and including the ... ...
Breaking Medicine Technology: