Navigation Links
Stomach Cancer Tumors Have Genetic Differences: Researchers
Date:8/3/2011

WEDNESDAY, Aug. 3 (HealthDay News) -- Stomach cancer tumors have genetic differences, which determine how they respond to treatment, researchers have found.

In identifying two distinct versions of the disease, scientists found that a certain regimen of chemotherapy is more effective on one tumor type, while another drug works best on the other. The study authors said their findings would help doctors more effectively treat gastric cancer patients.

"Our study is the first to show that a proposed molecular classification of gastric cancer can identify genomic subtypes that respond differently to therapies, which is crucial in efforts to customize treatments for patients," study senior author Dr. Patrick Tan, associate professor in the Cancer and Stem Cell Biology Program at the Duke-National University of Singapore (NUS) Graduate Medical School, said in a university news release.

A microscopic pathology test developed in the 1960s, known as the Lauren classification, is a general description (either intestinal or diffuse) of how well the tumor cells clump together. The Singapore-based team at the Duke-NUS Graduate Medical School, however, was able to distinguish gastric cancer tumors where the Lauren test could not.

"There is a general assumption in the field that intestinal and diffuse gastric cancers [as classified by Lauren] represent two very different versions of gastric cancer, and now genomic data confirms this by demonstrating that the two genomic subtypes have very different molecular patterns," said Tan.

In profiling 37 stomach cancer cell lines, the researchers found two distinct patterns. Moreover, in accurately defining these tumor subtypes, they were also able to observe differences in how well each responded to chemotherapy.

"The exact mechanistic reasons for this difference are currently unclear, and this is an area that we are actively working on," noted Tan, adding that the researchers a
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Surgically shrinking the stomach when conservative weight-loss treatments fail
2. DNA from common stomach bacteria minimizes effects of colitis, U-M study says
3. Could Stomach Pacemaker Be New Weight-Loss Tool?
4. New fusion gene plays role in some stomach cancers
5. Heavy Beer Drinking, Genetics May Raise Risk of Stomach Cancer
6. Detection of early gastric cancer using hydro-stomach CT
7. How to Cope With Stomach Flu Symptoms
8. Common stomach bacteria may fight off inflammatory bowel disease caused by Salmonella
9. Stomach Ulcers Sending Fewer Americans to the Hospital
10. Western Diet Populates Kids Stomachs With Bad Bacteria
11. Simpler and cheaper antibiotic prophylaxis with insertion of nutrition catheter in the stomach
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Stomach Cancer Tumors Have Genetic Differences: Researchers
(Date:7/31/2015)... ... July 31, 2015 , ... Patients with higher levels of a ... published today in Nature Communications and led by researchers from the Icahn School of ... in the gene RTN1 led to greater production of the related RNT1 protein, which ...
(Date:7/31/2015)... ... ... Indosoft, Inc., is pleased to announce a major update to its agent ... center ACD system for Asterisk-based call centers . The new features make it ... the agent only when wanted, and allows for validation of data as the agent ...
(Date:7/31/2015)... ... 31, 2015 , ... According to WFLA on July 16th, Sarasota ... and eventual overdoses. Thricefold deaths have held steady over the last “couple of months” ... heroin epidemic, which was spurred by the crackdown of prescription painkillers. Many users who ...
(Date:7/31/2015)... ... July 31, 2015 , ... ... Medicine Practice, and Hospital Medicine Practice, is pleased to announce that it has ... mobile application format available on iPhones, iPads, and Android smartphones and tablets. ...
(Date:7/31/2015)... ... July 31, 2015 , ... An article ... NBC talked about a woman’s unfortunate experience having cosmetic skin procedures done by ... which resulted in blistering, swelling, bruising, and pain. This woman’s experience is only ...
Breaking Medicine News(10 mins):Health News:Mount Sinai Researchers Find Key Gene Drives Kidney Disease Severity 2Health News:Mount Sinai Researchers Find Key Gene Drives Kidney Disease Severity 3Health News:Q-Suite 5.9 Adds Validation Tools to Call Center Software Agent Screen 2Health News:Sarasota Sufferers Increased Heroin Overdoses and Deaths 2Health News:Sarasota Sufferers Increased Heroin Overdoses and Deaths 3Health News:EB Medicine Launches Mobile Application for Pediatric Emergency Medicine 2Health News:EB Medicine Launches Mobile Application for Pediatric Emergency Medicine 3Health News:Dermatologists Discuss Rise in Unqualified Practitioners of Cosmetic Dermatology 2Health News:Dermatologists Discuss Rise in Unqualified Practitioners of Cosmetic Dermatology 3
... to Raise $260,000 for ORBIS Children,s Eye Care Project ... ... Nyan and Lehka Pendyala, ages 8 and 6,will launch a kid-inspired and ... childhood blindness. Their,ultimate goal is to raise $260,000 for a specialized pediatric ...
... Human Health Effects of Fruit and Vegetables (FAV) is ... from October 9 till 13 in Houston, TX. ... & bridge the communication gap between the agricultural sciences, ... is unique since scientists, students, industry, commodity groups and ...
... 9 Nurse Savvy Research Group is,an exciting ... is an online medical information service established to,provide ... to which,doctors they would choose for a variety ... The data gathered for the website will be,obtained ...
... ... Saudi Arabia, SOMERSET, N.J., Oct. ... AWT International, Inc.,has opened new sales offices in Saudi Arabia. ... healthcare industry. The Company has hired 2 highly experienced executives ...
... Two UT Southwestern Medical Center researchers a distinguished ... elected to the Institute of Medicine, a component of ... Luis Parada, professor and chairman of developmental biology, and ... among 65 new national members and four foreign associates ...
... DIEGO, Oct. 9 Many Americans are obsessed with,staying ... about being,mentally fit. More Americans are becoming aware of ... where knowledge, intelligence, and quick,wits are rewarded. Being mentally ... effectively train your brain have been lacking,until recently. ...
Cached Medicine News:Health News:Elementary School Students to Launch 'Kids for Sight' Campaign, to Inspire Other Kids to Pay it Forward 2Health News:Elementary School Students to Launch 'Kids for Sight' Campaign, to Inspire Other Kids to Pay it Forward 3Health News:Nursesavvy.com Promoting Quality Healthcare for Everyone 2Health News:AWT, Inc. Continues Rapid Expansion in Middle East 2Health News:AWT, Inc. Continues Rapid Expansion in Middle East 3Health News:2 UT Southwestern researchers elected to National Academy of Sciences' Institute of Medicine 2Health News:2 UT Southwestern researchers elected to National Academy of Sciences' Institute of Medicine 3Health News:Online Game from BrainGrade Can Raise Brain I.Q. 2
(Date:7/30/2015)... 2015 Edwards Lifesciences Corporation (NYSE: EW ), ... hemodynamic monitoring, today announced that Robert A. Ingram ... "Bob is an ardent champion for innovation in the lifesciences ... him on Edwards, board as we pursue our focused innovation ... CEO.  "Bob has provided a valuable perspective to our board, ...
(Date:7/30/2015)... SAN DIEGO , July 30, 2015 ... announced it has signed a definitive agreement ... provider of non-invasive ventilation and sleep-disordered breathing ... strong clinical, innovation and market reputation in China, combined with ResMed,s global leadership ... of people in China ...
(Date:7/30/2015)... 2015  ResMed Inc. (NYSE: RMD ) today ...  Revenue for the quarter was $453.1 million, a 9 ... 2014 (a 17 percent increase on a constant currency ... quarter ended June 30, 2014.  Diluted earnings per share ... ended June 30, 2014.  The results ...
Breaking Medicine Technology:ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 2ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 3ResMed Inc. Announces Results for the Fourth Quarter and Fiscal Year 2015 2ResMed Inc. Announces Results for the Fourth Quarter and Fiscal Year 2015 3ResMed Inc. Announces Results for the Fourth Quarter and Fiscal Year 2015 4ResMed Inc. Announces Results for the Fourth Quarter and Fiscal Year 2015 5ResMed Inc. Announces Results for the Fourth Quarter and Fiscal Year 2015 6ResMed Inc. Announces Results for the Fourth Quarter and Fiscal Year 2015 7ResMed Inc. Announces Results for the Fourth Quarter and Fiscal Year 2015 8ResMed Inc. Announces Results for the Fourth Quarter and Fiscal Year 2015 9ResMed Inc. Announces Results for the Fourth Quarter and Fiscal Year 2015 10ResMed Inc. Announces Results for the Fourth Quarter and Fiscal Year 2015 11ResMed Inc. Announces Results for the Fourth Quarter and Fiscal Year 2015 12ResMed Inc. Announces Results for the Fourth Quarter and Fiscal Year 2015 13ResMed Inc. Announces Results for the Fourth Quarter and Fiscal Year 2015 14ResMed Inc. Announces Results for the Fourth Quarter and Fiscal Year 2015 15ResMed Inc. Announces Results for the Fourth Quarter and Fiscal Year 2015 16
... Volk G-1 trabeculum provides the highest magnification of ... viewing and treating the trabecular meshwork. One ... anterior chamber angle while the central portion of ... posterior pole for signs of glaucoma and other ...
... Fluid eXchange) Lens is a ... use in an air-filled eye. ... as a primary air-fluid exchange ... and sutureless design make it ...
... Prism is designed for ... are recommended for tractional ... etc.) and Rhegmatogenus retinal ... used for panretinal photocoagulation ...
The Chalam Mid Field lens can be used for air/gas exchange and has a bi-concave design to provide the widest field available in a direct image surgical lens. This lens was developed with K.V. Chalam,...
Medicine Products: