Navigation Links
Still holding their breath: Mortality on lung transplant wait list remains high for some
Date:8/23/2009

simultaneously examined two outcomesdeath versus transplantfor the nearly 8,000 registrants diagnosed with COPD, IPF, CF or IPAH and compared the "Pre-LAS" period (from May 4, 2002 to May 3, 2005) to the "post-LAS" (from May 4, 2005 to May 3, 2008.)

They were not surprised to find that implementation of LAS was associated with an overall increased likelihood of transplantation and decreased risk of death. However, further analysis revealed that the risk of death for each individual disease except IPAH decreased significantly.

Before the implementation of LAS, the likelihood of transplant was highest for COPD patients and lowest for IPAH patients, even after adjusting for confounding variables including age, blood type and type of transplant. After the LAS, IPAH patients remained the least likely to receive a transplant, despite being at greater risk of death while on the waiting list than either COPD patients or those with IPF.

"The fact that the LAS has led to an overall improvement in the time to transplantation is not particularly surprising," noted Dr. Chen. "But we would hope that those changes would have positively affected all lung transplant candidates, whereas we found distinct differences in the impact according to disease, particular for pulmonary arterial hypertension."

A possible explanation of these findings is the fact that key prognostic indicators in IPAH are not considered under the LAS algorithm. "Hemodynamic variables currently included in LAS, such as pulmonary capillary wedge pressure, provide little information for patients with IPAH," wrote Dr. Chen. "In contrast, mean right arterial pressure and cardiac index, which are known to be strong predictors of mortality for patients with IPAH, are not utilized."

"The LAS has had a positive impact on the majority of wait-listed patients in the U.S.," wrote Kevin Chan, M.D., of the University of Michigan, in an accompanying editorial. "Although the overal
'/>"/>

Contact: Keely Savoie
ksavoie@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. UCLA researchers identify markers that may predict diabetes in still-healthy people
2. Obesity Rate in U.S. Still Climbing
3. Childhood asthma still inappropriately treated in the UK
4. New Survey Shows Americans are Still Concerned About Food Safety, Yet Still Not Smart About What They Like to Eat
5. Amid Improving Life Expectancy Rates, Risk of Premature Death is Still Significant for Americans, New Study Shows
6. Health Insurance Premiums Rise 6.1 Percent in 2007, Less Rapidly Than in Recent Years But Still Faster Than Wages and Inflation
7. Tickets Still Available for Detroit Uncorked;
8. Home Care Agencies Responding to Patients Needs - Still Have Room for Improvement
9. Stille and Enova Form Strategic Partnership to Introduce Worlds Brightest LED Cordless Surgical Headlights Into Europe and Japan
10. Older blacks and Latinos still lag whites in controlling diabetes
11. Clinical Trials Directive still hampering academic medical research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... Two recent studies indicate that previously untreated ... more abused as children than those without these disorders. And ... ADHD children reduces their otherwise higher risk of later ... causation. , Since over 25% of the population suffer from ... and best treatment for these disorders so as to prevent ...
(Date:7/22/2014)... A new and technologically unique procedure ... results that are surprising even the most skeptical plastic ... with radio frequency, ThermiTight has been dubbed “InjectableRF” because ... skin to “inject” heat to the tissues which cause ... treatment solution for skin laxity produces results in weeks, ...
(Date:7/21/2014)... cancer cells could boost the effectiveness of chemotherapy to ... new study reports. , Scientists at The Institute of ... engineered version of the virus used to vaccinate against ... isolated limb perfusion chemotherapy given directly to blood ... alternative to amputation was more effective in rats ...
(Date:7/21/2014)... 22, 2014 Recently, Stwd.co.uk, a popular supplier ... wedding dresses. Additionally, the company’s chief executive officer has stated ... prices, up to 58% off. , “All our new and ... offer is launched to bring huge benefits to worldwide customers. ... cheap wedding outfits. By the way, we offer custom made ...
(Date:7/21/2014)... As reported by CBS Local Pittsburgh ... Raise Addiction Awareness (7/15), thrill-seeking participants raised $100,000 to ... building in Downtown Philly. 100 people, including some well-known ... Westin Convention Center Hotel. Some of the participants shared ... participated because his son killed himself after a long ...
Breaking Medicine News(10 mins):Health News:New Studies Reporting a Higher Incidence of Child Abuse in ADHD and Dyslexia Suggest a Need for Early Medical Treatment, Notes Dr. Harold Levinson 2Health News:New Studies Reporting a Higher Incidence of Child Abuse in ADHD and Dyslexia Suggest a Need for Early Medical Treatment, Notes Dr. Harold Levinson 3Health News:New Studies Reporting a Higher Incidence of Child Abuse in ADHD and Dyslexia Suggest a Need for Early Medical Treatment, Notes Dr. Harold Levinson 4Health News:New Minimally Invasive Procedure, ThermiTight, “Injects” Radio Frequency to Treat Skin Laxity 2Health News:Viral therapy could boost limb-saving cancer treatment 2Health News:Viral therapy could boost limb-saving cancer treatment 3Health News:2014 Cheap Wedding Dresses, Newest Items Offered by Professional Company Stwd.co.uk 2Health News:100 People Climb Down Building to Raise Drug Addiction Awareness in Philadelphia 2Health News:100 People Climb Down Building to Raise Drug Addiction Awareness in Philadelphia 3
... The Healthcare Group at Frost ... Quarterly Analyst Briefing Presentation on the Pharmaceutical CRM Market ... 4 p.m. GMT. (Logo: http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO )2008 has ... CRM market. The pharmaceutical industry is adopting a cautious ...
... Day is opportunity to highlight advances for chronic condition; third FDA-approved ... ... 27, 2009 -- Each new treatment that becomes available is a ... according to the National Fibromyalgia Association (NFA), which is ...
... Solutions has announced the release of VitalCenter, a business continuity solution ... electronic health records to provide patient care. , ... ... to their patients, charts, even when the EHR is unavailable. ...
... April 27, 2009The American Urological Association (AUA) today issued ... issued by other major groups about prostate cancer ... be offered to well-informed, men aged 40 years or ... 10 years. The PSA test, as well as how ...
... April 26, 2009) A team of scientists at ... at Princess Margaret Hospital and international collaborators have discovered ... that could be included in new clinical trials that ... The findings, published online today in Nature Medicine ...
... 2009Tadalafil may improve lower urinary tract symptoms in men ... San Antonia and Indianapolis will present these findings during ... Association (AUA). , In this study, researchers randomly ... older than 40 years and at least a six ...
Cached Medicine News:Health News:Frost & Sullivan: The Pharmaceutical Customer Relationship Management Market - What are the Emerging Trends and Opportunities? 2Health News:Frost & Sullivan: The Pharmaceutical Customer Relationship Management Market - What are the Emerging Trends and Opportunities? 3Health News:Treatment Options Increase For Millions with Fibromyalgia 2Health News:Treatment Options Increase For Millions with Fibromyalgia 3Health News:Galen Healthcare Solutions Launches Electronic Health Record Downtime Solution 2Health News:AUA counters mainstream recommendations with new best practice statement on PSA testing 2Health News:AUA counters mainstream recommendations with new best practice statement on PSA testing 3Health News:AUA counters mainstream recommendations with new best practice statement on PSA testing 4Health News:Scientists discover how to improve immune response to cancer at Princess Margaret Hospital 2
(Date:7/21/2014)...  PowerVision, Inc., a medical device company developing ... announced that Douglas D. Koch , M.D., ... and Professor of Ophthalmology, at Baylor College of ... As a recipient of several ... Lifetime Achievement award, Koch will join the distinguished ...
(Date:7/21/2014)... July 21, 2014  AVT, Inc. (OTC Markets: ... retailing, micro-stores, custom vending machines and kiosks, commented ... medicine dispensing systems, which can be used by ... marijuana dispensaries. AVT,s newly designed systems provide for ... and regulated products. "We are getting ...
(Date:7/21/2014)... July 21, 2014  Avanir Pharmaceuticals, Inc. (NASDAQ: ... and Drug Administration (FDA) accepted the company,s Investigational New ... the safety and efficacy of AVP-786, Avanir,s next generation ... AVP-786 for the adjunctive treatment of major depressive disorder ... "The endorsement of this Phase II study ...
Breaking Medicine Technology:PowerVision Appoints Ophthalmology Thought Leader Douglas D. Koch, M.D. to its Scientific Advisory Board 2PowerVision Appoints Ophthalmology Thought Leader Douglas D. Koch, M.D. to its Scientific Advisory Board 3PowerVision Appoints Ophthalmology Thought Leader Douglas D. Koch, M.D. to its Scientific Advisory Board 4Technology Driving Cannabis Industry 2Avanir Pharmaceuticals Announces FDA Acceptance of IND for AVP-786 for the Adjunctive Treatment of Major Depressive Disorder 2Avanir Pharmaceuticals Announces FDA Acceptance of IND for AVP-786 for the Adjunctive Treatment of Major Depressive Disorder 3Avanir Pharmaceuticals Announces FDA Acceptance of IND for AVP-786 for the Adjunctive Treatment of Major Depressive Disorder 4Avanir Pharmaceuticals Announces FDA Acceptance of IND for AVP-786 for the Adjunctive Treatment of Major Depressive Disorder 5
... base with vacuum stage, porous vacuum plate, reservoir ... instructions. The Model 785 vacuum blotter quickly ... agarose gel onto a nylon membrane. Because it ... nucleic acid samples can be separated on a ...
... regulator. The Model 785 vacuum blotter ... from an agarose gel onto a nylon ... min for transfer, the nucleic acid samples ... to a membrane, and the hybridization reaction ...
Inquire...
... proven electrophoretic transfer apparatus incorporating state-of-the-art plate electrodes ... allows for a very close positioning of the ... power source such as a battery charger, creates ... exceptionally rapid and exact electrophoretic transfer. ...
Medicine Products: