Navigation Links
Still holding their breath: Mortality on lung transplant wait list remains high for some
Date:8/23/2009

simultaneously examined two outcomesdeath versus transplantfor the nearly 8,000 registrants diagnosed with COPD, IPF, CF or IPAH and compared the "Pre-LAS" period (from May 4, 2002 to May 3, 2005) to the "post-LAS" (from May 4, 2005 to May 3, 2008.)

They were not surprised to find that implementation of LAS was associated with an overall increased likelihood of transplantation and decreased risk of death. However, further analysis revealed that the risk of death for each individual disease except IPAH decreased significantly.

Before the implementation of LAS, the likelihood of transplant was highest for COPD patients and lowest for IPAH patients, even after adjusting for confounding variables including age, blood type and type of transplant. After the LAS, IPAH patients remained the least likely to receive a transplant, despite being at greater risk of death while on the waiting list than either COPD patients or those with IPF.

"The fact that the LAS has led to an overall improvement in the time to transplantation is not particularly surprising," noted Dr. Chen. "But we would hope that those changes would have positively affected all lung transplant candidates, whereas we found distinct differences in the impact according to disease, particular for pulmonary arterial hypertension."

A possible explanation of these findings is the fact that key prognostic indicators in IPAH are not considered under the LAS algorithm. "Hemodynamic variables currently included in LAS, such as pulmonary capillary wedge pressure, provide little information for patients with IPAH," wrote Dr. Chen. "In contrast, mean right arterial pressure and cardiac index, which are known to be strong predictors of mortality for patients with IPAH, are not utilized."

"The LAS has had a positive impact on the majority of wait-listed patients in the U.S.," wrote Kevin Chan, M.D., of the University of Michigan, in an accompanying editorial. "Although the overal
'/>"/>

Contact: Keely Savoie
ksavoie@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. UCLA researchers identify markers that may predict diabetes in still-healthy people
2. Obesity Rate in U.S. Still Climbing
3. Childhood asthma still inappropriately treated in the UK
4. New Survey Shows Americans are Still Concerned About Food Safety, Yet Still Not Smart About What They Like to Eat
5. Amid Improving Life Expectancy Rates, Risk of Premature Death is Still Significant for Americans, New Study Shows
6. Health Insurance Premiums Rise 6.1 Percent in 2007, Less Rapidly Than in Recent Years But Still Faster Than Wages and Inflation
7. Tickets Still Available for Detroit Uncorked;
8. Home Care Agencies Responding to Patients Needs - Still Have Room for Improvement
9. Stille and Enova Form Strategic Partnership to Introduce Worlds Brightest LED Cordless Surgical Headlights Into Europe and Japan
10. Older blacks and Latinos still lag whites in controlling diabetes
11. Clinical Trials Directive still hampering academic medical research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... Unidesk Corporation today announced that the ... its inaugural class in August 2013, has successfully ... bring your own device (BYOD) and deliver a ... solution, comprised of Citrix XenDesktop and ... storage infrastructure and Unidesk virtual desktop ...
(Date:12/17/2014)... No matter how far modern medicine advances, ... head louse parasite—a common childhood malady and a source ... six and twelve million individuals will suffer an infestation. ... company comes to the rescue, providing an all-natural treatment ... track record of customer service, and effectiveness in getting ...
(Date:12/17/2014)... Expectant parents should leave prenatal picture-taking to medical professionals, ... of ultrasound imaging and heartbeat monitors to get "keepsake" ... warns. "Although there is a lack of ... heartbeat monitors, prudent use of these devices by trained ... biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. ... in America, and work commitment is a big reason why, ... killer," said Dr. Mathias Basner, an assistant professor of sleep ... School of Medicine. A time-use survey of nearly 125,000 ... the main activity exchanged for sleep. Short sleepers -- those ...
(Date:12/15/2014)... December 15, 2014 South Florida’s leading urgent ... holidays can be a daze of hassle, hustle, and bustle ... while decking halls, to burns when making special meals and ... that can happen at any time. To prevent this season ... has made a list of helpful and healthful holiday tips ...
Breaking Medicine News(10 mins):Health News:Alabama College of Osteopathic Medicine Deploys Desktop Virtualization Solution from Citrix, Dell and Unidesk 2Health News:Alabama College of Osteopathic Medicine Deploys Desktop Virtualization Solution from Citrix, Dell and Unidesk 3Health News:Lice Troopers Announces New Lice Treatment Clinic in Coral Gables to Service Key Biscayne, Coconut Grove, Kendall, Brickell & South Miami 2Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3
... Dec. 1 Effective December 1, 2008, NHS Human ... human services in the country, will expand operations to ... Human Services Center (TCHSC), headquartered in Carbondale, PA. ... has been looking for ways to deal with increasing ...
... have to lose your safety net... , says nonprofit founder ... Dec. 1 With U.S. unemployment at a record 6.5% ... to grow. However, armed with statistics that nearly one-third of ... but don,t know it, Phil Lebherz, executive director of the ...
... VAInfectious disease experts warn that new drugs are urgently ... hospital infections and increasingly escape the effects of antibiotics. ... been dubbedare still on the loose more than four ... first drew attention to the growing shortage of effective ...
... the driving force for a safe return to the roadways ... 1 /PRNewswire-USNewswire/ - - While many patients recovering from ... get back into their old routines, knowing when it,s safe ... a difficult and complex decision to make. A discussion of ...
... Statement Highlights Women,s Unmet Needs for HIV Prevention, Calls on ... , (Para tener acceso a una ... www.preventionnow.net .) , , ... represent Latin American women and Latina women in the United ...
... OF SCIENTIFIC DISCOVERY IN MOLECULAR IMAGING , ... Society of North America (RSNA) honored Ralph Weissleder, MD, PhD, ... annually to one scientist who has made original significant contributions ... Dr. Weissleder is Professor at Harvard Medical School , ...
Cached Medicine News:Health News:NHS Human Services to Take Over Tri County Human Services Center 2Health News:Holding On to Your Health Coverage: 5 Steps to Consider If You've Been Laid-Off 2Health News:Holding On to Your Health Coverage: 5 Steps to Consider If You've Been Laid-Off 3Health News:No ESKAPE! New drugs against MRSA, other superbugs still lacking 2Health News:No ESKAPE! New drugs against MRSA, other superbugs still lacking 3Health News:No ESKAPE! New drugs against MRSA, other superbugs still lacking 4Health News:When to Get Back Behind the Wheel While on the Road to Recovery 2Health News:When to Get Back Behind the Wheel While on the Road to Recovery 3Health News:Latin American and U.S. Latina Women Unite to Demand Access to the Female Condom 2Health News:Latin American and U.S. Latina Women Unite to Demand Access to the Female Condom 3Health News:VisEn Co-Founder Named Radiologic Society's 'Outstanding Researcher of the Year' 2Health News:VisEn Co-Founder Named Radiologic Society's 'Outstanding Researcher of the Year' 3
(Date:12/17/2014)... and RALEIGH, N.C. , ... Communications, LLC (CTMC), and Integrated Clinical Trial Services, ... and retention for clinical trials announce that they ... Trial Marketing Services (i-CTMS). i-CTMS will provide a ... to pharmaceutical, biotechnology and medical device companies. ...
(Date:12/15/2014)... , Dec. 12, 2014 Research and Markets ... the "Electrocardiogram (ECG) Devices - Global Trends, Estimates ... http://photos.prnewswire.com/prnh/20130307/600769 Global ... million by 2016. The North America ... market share while Europe claims ...
(Date:12/15/2014)... Israel , Dec. 15, 2014  Immune Pharmaceuticals Inc. ... that its Board of Directors has elected Mr. Daniel Kazado ... who continues as Chief Executive Officer of Immune. Mr. Kazado ... 2013. Immune,s new Chairman, Mr. Daniel Kazado ... shareholders and to continue to support the strategic vision of ...
Breaking Medicine Technology:Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 2Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 3Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 2Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 3Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 4Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 2Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 3Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 4
... Oct. 21 The U.S. Food and Drug ... been added to the label for the HIV ... effects on the heart when used with Norvir ... http://photos.prnewswire.com/prnh/20090824/FDALOGO ) (Logo: http://www.newscom.com/cgi-bin/prnh/20090824/FDALOGO ...
... 21 Span-America Medical Systems, Inc. (Nasdaq:  SPAN) will ... conference call on Tuesday, November 2, 2010, covering results ... be released after the regular close of trading the ... conference call will be available online at  www.spanamerica.com ...
Cached Medicine Technology:New Label Changes for Commonly Prescribed HIV Drug Invirase 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: