Sticky blood protein yields clues... (n SERT as well as engineering mice that ...)

Sticky blood protein yields clues to autism

Date:3/4/2008

n SERT as well as engineering mice that express human integrin beta3 mutations.

At a February Keystone Conference, Blakely described preliminary studies with mice that his lab has engineered to express hyperactive SERT mutations. Together, these new animal models offer an unprecedented opportunity to peel away the complexity of autism and possibly develop new therapies, he said.

This research also may uncover new ways of treating depression. Current antidepressant mechanisms still essentially work in the same way they did 25 years ago by targeting transporter uptake of neurotransmitter directly, Carneiro said. Now we may have a completely new way to go about it.

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Contact: Craig Boerner
craig.boerner@vanderbilt.edu
615-322-4747
Vanderbilt University Medical Center
Source:Eurekalert

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