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Steve Jobs, Visionary Leader of Apple Inc., Dies at 56
Date:10/7/2011

roblems with the [liver] transplant is that now you are on immunosuppressant drugs, and while they keep you from rejection or destroying the liver, the immune system also would have helped deal with tumors," he explained.

Devoe said a liver transplant is a treatment when "your back's against the wall," and isn't expected to cure neuroendocrine cancer, so very few are done.

"The fact that the disease came back [was] not surprising," he said.

These treatments won't cure the disease, but they may slow its progression, Devoe said. "It may extend the life of patients. But at this point, your best treatments are behind you and survival may be under a year or two," he said. "It's clearly incurable."

Doctors don't really know what causes neuroendocrine tumors. In the past year, the U.S. Food and Drug Administration approved two new drugs for neuroendocrine tumors -- sunitinib and everolimus.

In a commencement address in 2005 to Stanford University graduates, Jobs said: "No one wants to die. Even people who want to go to heaven don't want to die to get there. And yet death is the destination we all share. No one has ever escaped it."

More information

To learn more about neuroendocrine pancreatic tumors, visit Stanford University School of Medicine.

SOURCES: Steven Libutti, M.D., director, Montefiore Einstein Center for Cancer Care, New York City; David M. Levi, M.D., professor, clinical surgery, liver and GI transplantation, University of Miami Miller School of Medicine; Craig Devoe, M.D., department of medicine, North Shore-LIJ Health System, New Hyde Park, N.Y.; The New York Times


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