Navigation Links
Steve Jobs, Visionary Leader of Apple Inc., Dies at 56
Date:10/7/2011

By Steven Reinberg
HealthDay Reporter

WEDNESDAY, Oct. 5 (HealthDay News) -- Steve Jobs, the visionary leader of Apple Inc. who introduced the world to personal computers, then the iPod, the iPhone and the iPad, died on Wednesday following a long battle with cancer.

He was 56.

"Apple has lost a visionary and creative genius, and the world has lost an amazing human being," the company said in a statement it posted on its website Wednesday night. The statement did not cite a specific cause of death.

Jobs announced in August that he was stepping down as head of the hugely successful technology company he co-founded in a northern California garage 35 years ago. The announcement was thin on details, although speculation immediately turned to his ongoing health problems.

He first had surgery for a rare form of pancreatic cancer back in 2004, received a liver transplant in 2009 and took three medical leaves at Apple before turning over the helm to Timothy D. Cook, then chief operating officer, in August. But, even after he left, Jobs was still engaged in the company's affairs, The New York Times reported Wednesday night.

In a letter to Apple's board of directors in August, Jobs said he "always said if there ever came a day when I could no longer meet my duties and expectations as Apple's CEO, I would be the first to let you know. Unfortunately, that day has come."

This much was known about the health of Jobs, a legendarily private man: Since 2004, he had been fighting a rare form of pancreatic cancer called neuroendocrine cancer.

Although neither Apple nor Jobs' family has given a cause of death, a cancer expert speculated that Jobs' death was due to the neuroendocrine cancer.

"I have never treated him or seen his medical records, but it certainly fits with the treatments that have been acknowledged," said Dr. Steven Libutti, director of the Montefiore Einstein Center for Cancer Care in New York City.

Patients who have had surgery to remove the tumor, but have had the cancer return, often have the cancer come back in the liver. That is probably why Jobs had a liver transplant, Libutti said.

"My speculation is that the tumor returned after the liver transplant and he succumbed to recurrent disease, that would be my bet," he said.

Pancreatic cancer expert Dr. Craig Devoe, from the department of medicine at North Shore-LIJ Health System in New Hyde Park, N.Y., said that "neuroendocrine tumors are uncommon, with only a few thousand cases a year."

For those that affect the pancreas, the numbers are even lower with fewer than 1,000 cases a year in the United States. In contrast, there are around 40,000 cases of other pancreatic cancers a year, Devoe said.

Dr. David M. Levi, a professor of clinical surgery, liver and GI transplantation at the University of Miami Miller School of Medicine, said neuroendocrine cancer "is an unusual tumor. It can arise in a number of places, including the pancreas." Such tumors can also start in the lungs.

It's one of the few tumors that can benefit -- to some extent -- from a transplant, Levi said. Jobs' cancer started in the pancreas and then spread to the liver, making the liver transplant an option, Levi said, adding he has treated patients with this type of cancer and done liver transplants.

While the prognosis for neuroendocrine cancer is often better than for the more common type of pancreatic cancer, in which patients generally live less than a year after diagnosis, neuroendocrine cancer "can also be bad," Levi said.

Neuroendocrine cancer can return after treatment, Levi explained. And while a liver transplant can be effective, "it is not as great a picture as we first thought," he said. "A lot of these patients who have transplants eventually do recur."

"The vast majority of patients that have recurrent disease will die of their disease. One of the problems with the [liver] transplant is that now you are on immunosuppressant drugs, and while they keep you from rejection or destroying the liver, the immune system also would have helped deal with tumors," he explained.

Devoe said a liver transplant is a treatment when "your back's against the wall," and isn't expected to cure neuroendocrine cancer, so very few are done.

"The fact that the disease came back [was] not surprising," he said.

These treatments won't cure the disease, but they may slow its progression, Devoe said. "It may extend the life of patients. But at this point, your best treatments are behind you and survival may be under a year or two," he said. "It's clearly incurable."

Doctors don't really know what causes neuroendocrine tumors. In the past year, the U.S. Food and Drug Administration approved two new drugs for neuroendocrine tumors -- sunitinib and everolimus.

In a commencement address in 2005 to Stanford University graduates, Jobs said: "No one wants to die. Even people who want to go to heaven don't want to die to get there. And yet death is the destination we all share. No one has ever escaped it."

More information

To learn more about neuroendocrine pancreatic tumors, visit Stanford University School of Medicine.

SOURCES: Steven Libutti, M.D., director, Montefiore Einstein Center for Cancer Care, New York City; David M. Levi, M.D., professor, clinical surgery, liver and GI transplantation, University of Miami Miller School of Medicine; Craig Devoe, M.D., department of medicine, North Shore-LIJ Health System, New Hyde Park, N.Y.; The New York Times


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Steve Jobs Faces Uphill Battle Against Cancer: Experts
2. Football Legend Steve Young Urges Kids, Parents to Play It Safe
3. Stevens Dr. A. K. Ganguly receives Topliss Award Lecture from University of Michigan
4. Steve Waugh To Launch Inaugural Men's Health Screening Event In Wollongong
5. Steven Zoernack and The Bullion Fund Deploy Equity Long/Short Strategy with Apple (AAPL) and Research in Motion (RIMM)
6. Recommended Dental Care for Chemotherapy Patients -- Advice from Steven McConnell, DDS
7. Ingenious Med Founder, Steven Liu, Earns Senior Fellow in Hospital Medicine Designation
8. Stevens Hospital One Step Closer to Affiliation with Swedish
9. Governor Rendell Proposes Budget With No Tax Increase, More Money for Public Schools, Strategy for Jobs, Plan to Address Future Deficits
10. The Practical Visionary Offers Eight Keys to Surviving and Thriving in the 21st Century
11. Slumdog Millionaire Put Spotlight on Slums in Developing World Now, Health Visionary Helps Turn Urban Blight into Hope
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Steve Jobs, Visionary Leader of Apple Inc., Dies at 56
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified ... be personalized through a fitness app. The fitness app plans to fix the two major ... only offer a one size fits all type program , They don’t eliminate ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture ... said Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package ... Final Cut Pro X . Simply select a ProHand generator and drag it ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, whether ... latter, setting the bar too high can result in disappointment, perhaps even self-loathing. However, ... their goal. , Research from PsychTests.com reveals that behind the tendency ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... Conference and Scientific Sessions in Dallas that it will receive two significant new ... the grants came as PHA marked its 25th anniversary by recognizing patients, medical ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their ... Award, an essay contest in which patients and their families pay tribute to a ... the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 ... the "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural ... Structural electronics involves electronic and/or ... protective structures, replacing dumb structures such as vehicle ...
(Date:6/24/2016)... ANDOVER, Mass. and SAN CLEMENTE, Calif. ... California -based mobile pulmonary function testing company, is now ... portable PFT devices developed by ndd Medical Technologies , Inc. ... PFT testing done in hospital-based labs.  Thanks to ndd,s EasyOne PRO ... CA , can get any needed testing done in the ...
(Date:6/24/2016)... --  Pulmatrix, Inc ., (NASDAQ: PULM ), ... today that it was added to the Russell Microcap ... set of U.S. and global equity indexes on June ... for Pulmatrix," said Chief Executive Officer Robert Clarke ... in developing drugs for crucial unmet medical needs, and ...
Breaking Medicine Technology: