Navigation Links
Steroids ineffective in young children with wheeze

New research involving medical experts at The University of Nottingham has found that steroid tablets do not reduce the symptoms of virus-induced wheezing in pre-school children.

Researchers from the universities of Nottingham, Leicester and Bart's in London have been at the centre of a leading study to find out whether steroid medicine will relieve wheezing symptoms in children under five years of age.

There has been ongoing controversy in the medical community regarding how to best treat pre-school children who are admitted to hospital with severe wheezing. Steroids remain an important treatment for children with asthma but pre-school children with viral-induced wheeze, where symptoms are only associated with colds or flu and do not persist when the child is not infected with a virus, have also been treated with steroids in the past. This trial, funded by Asthma UK and published in the New England Journal of Medicine, definitively shows that steroid tablets do not help these children.

The research was carried out by Dr Alan Smyth, Associate Professor and Reader in Child Health, and Terence Stephenson, Professor of Child Health, at The University of Nottingham in collaboration with Dr Monica Lakhanpaul, Senior Lecturer from the University of Leicester and Consultant Paediatrician in Children's Community Health Service for Leicester, Leicestershire and Rutland and Professor Jonathan Grigg of Barts and the London School of Medicine and Dentistry.

Dr Alan Smyth said: "There may be some children for example those with a family history of asthma who benefit. However, young children who wheeze when they have a viral infection, do not seem to be helped by steroids."

Dr Monica Lakhanpaul added: "A number of treatments are used in children without strong evidence. This study demonstrates the need for further research in children not only to help us to find out treatments that work but also those that do not work which will then open the way to new research. It is sometimes difficult to recruit children to research studies but this study has been strongly supported by the families and children in the East Midlands and will help us to move another step closer to helping those children who suffer from wheeze."

Dr Mike Thomas, Chief Medical Advisor for Asthma UK, welcomed the study, which he said could have important implications for the medical community.

"Young children who only get wheezy when they have a cold or viral chest infection but can breathe normally at other times, are likely to grow-out of their tendency to wheeze by teenage years. It is important that we stop relying on a one-solution-fits-all which means that these young children are taking steroids unnecessarily, and to search for more effective treatments for these children," he added.


Contact: Dr. Alan Smyth
University of Nottingham

Related medicine news :

1. Steroids Seem Safe for Babies at Risk of Early Birth
2. Batters may achieve dramatic increases in home runs through steroids
3. Repeat steroids to premature infants linked to cerebral palsy
4. International Law Enforcement Operation Targets Underground Manufacture of Anabolic Steroids
5. Steroids Are Abused for Skin, Not Just Muscles
6. Research Indicates Nearly 25 Percent of Supplements Are Contaminated With Steroids, Stimulants and Banned Substances
7. ENDO 08: Latest news on hormones, steroids, obesity, diabetes and more
8. Corticosteroids of Little Use Against Childhood Meningitis
9. Kids at Risk: Report Identifies 150 Websites Selling Anabolic Steroids
10. Changes in sex steroids associated with menopause
11. Steroids aid recovery from pneumonia, UT Southwestern researchers say
Post Your Comments:
(Date:11/27/2015)... Canada (PRWEB) , ... November 28, 2015 , ... There ... do we outperform our billings from last year? , This question has not been ... organizations are coming to the retirement age and the younger workforce don’t share the ...
(Date:11/27/2015)... ... November 27, 2015 , ... The rapid ... America. As people age, more care is needed, especially with Alzheimer’s, dementia and ... professionals are being overworked. The forgotten part of this equation: 80 percent of ...
(Date:11/27/2015)... ... November 27, 2015 , ... Lizzie’s Lice Pickers just announced a special ... 10% off of their purchase of lice treatment product. In addition, customers will receive ... a company spokesperson. “Finding lice is a sure way to ruin the holidays, so ...
(Date:11/27/2015)... ... November 27, 2015 , ... Consistent with the ... 2016 Building Better Radiology Marketing Programs meeting will showcase some of ... 6, 2016, at Caesars Palace in Las Vegas with a pre-conference session on ...
(Date:11/27/2015)... ... November 27, 2015 , ... Keeping in mind challenges faced ... and wellness consultation, has collaborated with a leading web-based marketplace for extra-curricular activities ... by parents and bring advice from parenting experts within their reach. As a ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... Nederland, November 26, 2015 ... Een nieuwe aanpak combineert immunotherapie met Bremachlorin-photodynamische ... ) --> ...      (Photo: ) ... Universitair Medisch Centrum (LUMC) blijkt ...
(Date:11/26/2015)... Nov. 26, 2015 Research and Markets ... the "2016 Future Horizons and Growth Strategies ... Supplier Shares, Country Segment Forecasts, Competitive Intelligence, Emerging ... --> --> This ... the Japanese therapeutic drug monitoring market, including emerging ...
(Date:11/26/2015)... 2015 --> ... potential att använda SyMRI för att hitta ... patienter med multipel skleros (MS) eller hjärntumörmetastaser ... AB för att kunna använda SyMRI Research ... SyMRI kan man generera flera konstrastbilder från ...
Breaking Medicine Technology: