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Steroid treatment offers no benefit in preemies, Hopkins Children's study suggests
Date:10/9/2008

ed from this study because elevated cortisol concentration could be a consequence of the hemorrhage but not necessarily a trigger of it. Very high cortisol levels, above 62 micrograms per deciliter, appeared to heighten a baby's risk for severe brain hemorrhages, gastrointestinal perforation and death. For example, death occurred in 12 percent of infants who had low cortisol levels 48 hours after birth and in 13 percent of infants with midrange levels of cortisol, but in nearly 30 percent of infants with severely elevated cortisol levels at 48 hours of birth. Gastrointestinal bleeds occurred in 3 percent of infants with low cortisol levels at 48 hours of birth, in 9 percent of infants with cortisol levels in the mid-range, but in 24 percent of those with significantly elevated cortisol levels.


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Contact: Katerina Pesheva
epeshev1@jhmi.edu
410-516-4996
Johns Hopkins Medical Institutions
Source:Eurekalert

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