Navigation Links
Steroid treatment offers no benefit in preemies, Hopkins Children's study suggests
Date:10/9/2008

Results of a multicenter study led by Johns Hopkins Children's Center challenge the longstanding practice of treating premature babies with hydrocortisone, a steroid believed to fight inflammation and prevent lung disease. The researchers found that such treatment offers little or no benefit and that low cortisol levels are not even necessarily harmful. High cortisol levels, on the other hand, appeared to increase the risk of dangerous bleeding in the brain and require that babies be monitored aggressively to ward off life-threatening complications, according to the study published in the October issue of Pediatrics.

Premature babies and adults with a condition known as relative adrenal insufficiency have abnormally low levels of the stress hormone cortisol. The standard treatment for this condition in newborns has been hydrocortisone therapy. These findings, however, shed new light on the clinical meaning of low cortisol levels in preemies, showing that contrary to common belief, low blood concentrations of this hormone do not put extremely low-birth-weight babies (those born weighing less than 2.2 pounds) at higher risk for retinopathy of prematurity a potentially blinding eye condition inflammation and lung disease.

Researchers also found no difference in health outcomes between babies with low cortisol levels who were treated with hydrocortisone and those given a placebo. While hydrocortisone had no adverse effects on a baby's health, it also did nothing to prevent or reduce respiratory diseases, infections, hemorrhages or retinopathy.

"We were intrigued and somewhat surprised, but contrary to what we expected, low cortisol levels do not appear to be dangerous and may actually be the norm in premature babies," said study lead investigator Susan Aucott, M.D., a neonatologist at Hopkins Children's. "What this means is we should really think twice before rushing to treatment with hydrocortisone in our effort to 'correct' t
'/>"/>

Contact: Katerina Pesheva
epeshev1@jhmi.edu
410-516-4996
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Changes in sex steroids associated with menopause
2. Triax Pharmaceuticals Launches New Mid-Potency Corticosteroid Vehicle, Locoid Lotion 0.1%
3. Kids at Risk: Report Identifies 150 Websites Selling Anabolic Steroids
4. I Play Clean(TM) and Old Spice Kick Off Campaign Challenging High School Students to Pledge Against Steroid Use
5. Corticosteroids of Little Use Against Childhood Meningitis
6. ENDO 08: Latest news on hormones, steroids, obesity, diabetes and more
7. New steroid test uses oil exploration technique
8. Youth Impacted By Recent Mitchell Report on Major League Baseball Steroid Abuse
9. Pelosi Statement on Mitchell Report on Steroid Use in Baseball
10. Report Finds Widespread Steroid Use in Baseball
11. Steroid Fails to Ease Meningitis in Trials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/27/2014)... HealthDay Reporter WEDNESDAY, Nov. 26, 2014 ... safe and produces an immune system response that could protect ... results reported by the U.S. National Institutes of Health. ... vaccine paves the way for field-testing it in the Ebola-stricken ... as January, said Dr. Anthony Fauci, director of the NIH,s ...
(Date:11/27/2014)... NY (PRWEB) November 27, 2014 The founders ... offering stylish, comfortable and high functioning compression socks, are proud ... newly-released socks use an innovative Gradient Pressure (TM) knitting technology ... blood. , VIM & VIGR’s commitment to adding flair and ... as just functional recently caught the eye of a writer ...
(Date:11/27/2014)... November 27, 2014 Tylenol lawsuits ( ... allegedly injured by the medication are continuing to move ... is looking ahead to a status conference in December, ... Scheduling Order issued earlier this year, a conference in ... at 10:00 a.m. Items likely to be discussed at ...
(Date:11/27/2014)... 2014 “Wekho” was featured on NewsWatch as ... coolest mobile applications on the iOS, Android, and Windows markets. ... conducted the app review and shared with viewers ... , An interesting new way to travel and experience the ... It’s called Wekho and it’s a free geolocation app ...
(Date:11/27/2014)... 2014 Dr. Ronald Receveur, who has a ... few oral health tips before patients dig into the annual ... New Albany affordable cosmetic dentistry, and his staff ... and sugar. While the staff wishes everyone a happy and ... how patients can enjoy a feast that is also healthy ...
Breaking Medicine News(10 mins):Health News:Early Trial Promising for Ebola Vaccine 2Health News:Early Trial Promising for Ebola Vaccine 3Health News:VIM & VIGR Announces Launch of Men’s Line of Compression Socks 2Health News:Federal Litigation Presiding over Tylenol Lawsuits Looks Ahead to Status Conference in December, Bernstein Liebhard LLP Reports 2Health News:Federal Litigation Presiding over Tylenol Lawsuits Looks Ahead to Status Conference in December, Bernstein Liebhard LLP Reports 3Health News:A New Geolocation Mobile Application and was Featured on NewsWatch Television on October 30, 2014 2Health News:New Albany Dental Practice Offers Oral Health Tips For Thanksgiving 2Health News:New Albany Dental Practice Offers Oral Health Tips For Thanksgiving 3Health News:New Albany Dental Practice Offers Oral Health Tips For Thanksgiving 4
... The acquisition of Baptist Memorial Hospital in Forrest City, ... Systems. The acute health care centre which is 118-bedded ... Ark.). // ,In addition, some other assets would ... care center (Memphis-based Baptist Memorial Health Care Corp.) The ...
... new online application system for junior doctor posts is not ... the job prospects of many top students. This was the ... system being followed is the “Modernising Medical Careers system” which ... answers. ,The reason for this attack as claimed ...
... Scientists at the U.S. Department of Energy’s Brookhaven ... identifying the many species of microorganisms. They have ... of Applied Environmental Microbiology. Microbiology has many applications ... species useful for cleaning up contamination, to identify ...
... and weight loss failure turned to an online competition to ... a 4 month period.//, ,The competition hosted on WeightLossWars.com ... 25 miles, with the winner of the competition losing 9% ... Jen sending out invitations through WeightLossWars.com to her family and ...
... in matters of sleep till late the reason being ... ray of new light comes the IST project 'Sensation' ... different // countries, addressing sensing of physiological parameters, core ... a multipurpose sensing platform consisting of 17 micro sensors ...
... the protective clothing to astronauts going to space and ... the basis to design// protective clothing for fire fighters ... heat and dangerous circumstances. ,This project nicknamed ... that encompasses an inbuilt cooling system, with a technology ...
Cached Medicine News:Health News:Online recruitment criticised by doctors 2Health News:The Novel Cut and Splice Method Is Used To Recognize Different Microbes 2Health News:Sleep Science awakens from deep slumber! 2
(Date:11/26/2014)... , Nov. 26, 2014  CARsgen, a leader in ... immunotherapy to treat a variety of cancers, today announced ... BVCF, a China -based healthcare private ... company focused on the development of new therapeutics for ... Shanghai Cancer Institute and Shanghai Renji Hospital, the company ...
(Date:11/26/2014)... -- At the American Dental Association,s Annual Meeting in ... Group was honored to be part of the 2014 ... see and test the Best of Class winners and ... the latest developments in dental technology. This year, featured ... Caries Detection Device and Kerr Demi ™  Ultra ...
(Date:11/26/2014)... Colo. , Nov. 25, 2014   Heska Corporation ... "Heska" or the "Company"), a provider of advanced veterinary ... Robert Grieve , Executive Chair, will attend The Benchmark ... 2014. The one-on-one conference will be held at The Palmer ... from 8 a.m. to 2:30 p.m. Please email ...
Breaking Medicine Technology:CARsgen Completes Series A Financing 2KaVo Kerr Group Showcased in Pride Institute Technology Expo at ADA Annual Meeting 2KaVo Kerr Group Showcased in Pride Institute Technology Expo at ADA Annual Meeting 3Heska to Attend Benchmark Micro Cap Discovery Conference 2
... According to the American,Academy of Dermatology (AAD), ... an inflamed skin condition characterized by red, scaly,and ... which tend to,flare up in the winter months, ... Eczema Care Moisturizing Cream and Body Wash, formulated,with ...
... Infection Control, WASHINGTON, Jan. 10 To ... minimize risks during times,of health crisis, DuPont (NYSE: ... its,healthcare products, DuPont(TM) Corian(R) solid surface, has been ... department. The product,recently was incorporated into a children,s ...
Cached Medicine Technology:New AVEENO(R) Eczema Care Product Line Offers Breakthrough Formulas to Help Manage the Signs and Symptoms of Eczema 2DuPont Provides Technology for Washington Hospital Center's Emergency Department 2DuPont Provides Technology for Washington Hospital Center's Emergency Department 3DuPont Provides Technology for Washington Hospital Center's Emergency Department 4
PremierEdge™ Stab Knives - 30°....
DCR Set, Angled....
... Leica CM3050 S Cryostat Family ... excellent safety standards for practically ... The Leica CM3050 S is ... all cryosectioning research applications and ...
... is a freestanding cryostat with a ... and a radial cutting microtome. It ... wide range of specimens and materials ... in high biohazard risk laboratories where ...
Medicine Products: