Navigation Links
Steroid Concoction May Ease Sinusitis
Date:3/16/2009

Small study finds benefits, but drug does not have FDA approval for such use

MONDAY, March 16 (HealthDay News) -- A steroid nasal wash can help reduce symptoms of chronic sinusitis without affecting adrenal gland function, according to a small U.S. study.

Chronic sinusitis is a persistent inflammation of the nose and sinuses behind the nose that affects up to 14 percent of people in the United States, according to background information in the study.

The study included nine people who were told to use a nasal wash, composed of 0.25 milligrams of the corticosteroid budesonide and 5 milliliters of saline, in each nostril once a day for 30 days. The budesonide came in respules -- small, plastic, liquid-containing devices.

The researchers, from Washington University School of Medicine in St. Louis, said it was the first study to examine the safety of this type of nasal wash, noting that suppression of adrenal gland function is a known complication of budesonide.

All participants reported at least some improvement in their sinusitis symptoms, and their adrenal gland function was not affected, the study found. The results were published in the March issue of Otolaryngology -- Head & Neck Surgery.

"The clinical significance of this study is that budesonide nasal respules appear safe for short-term use for the relief of symptoms associated with chronic sinusitis," the researchers concluded. "Budesonide respules seem to provide an effective treatment option for the patient with chronic rhinosinusitis with minimal fear of systemic adverse effects."

The U.S. Food and Drug Administration has not approved budesonide as a nasal wash, which means the nasal wash used in this study would be an off-label use of the drug. The researchers urged doctors to warn patients about the risks associated with long-term use of budesonide, including decreased bone mineral density.

More information

The American Academy of Family Physicians has more about sinusitis.



-- Robert Preidt



SOURCE: JAMA/Archives journals, news release, March 16, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Steroids ineffective in young children with wheeze
2. 1 in 10 Ex-NFL Players Used Steroids, Poll Reports
3. Inhaled Corticosteroids Boost Pneumonia Risk in COPD
4. High and Super-High Potency Topical Corticosteroids Will Remain Decision Resources Clinical Gold Standard Through 2017 for the Treatment of Atopic Dermatitis
5. Additional Steroid Dose May Help Preemies
6. Twelve Indicted in Nationwide Anabolic Steroids Probe
7. Multiple Doses of Steroids Dont Help Preemies
8. Steroid After Tonsillectomy Raises Bleeding Risk
9. Steroid Inhalers Raise Pneumonia Risk for Lung Disease Patients
10. Study shows steroid therapies following transplant can be eliminated
11. Steroids aid recovery from pneumonia, UT Southwestern researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Steroid Concoction May Ease Sinusitis
(Date:4/25/2017)... (PRWEB) , ... April 25, 2017 , ... ... choose a modern procedure that achieves results in a fraction of the time ... Las Vegas, NV, with Significance Dental Specialists, now offers this revolutionary treatment with ...
(Date:4/25/2017)... ... April 25, 2017 , ... Buyers and sellers in ... to dispensaries and head shops –can’t help but be heartened by the industry’s current ... cannabis odor aptly described as “skunk smell.” At last they can simply, safely ...
(Date:4/25/2017)... ... April 25, 2017 , ... There is no better place in South ... special report in the May issue of Consumer Reports focused on heart health. ... results achieved during and after coronary bypass and aortic valve replacement procedures. , ...
(Date:4/24/2017)... ... April 24, 2017 , ... ... Bring Your Own Device (BYOD) capabilities at Telehealth 2.0, the American Telemedicine Association’s ... bundles, which pairs medical devices with a pre-programmed tablet in a remarkably easy-to-use ...
(Date:4/24/2017)... ... April 24, 2017 , ... As part of the nationwide Days of Remembrance ... of the Holocaust and Nazi persecution, Center for Medicine after the Holocaust (CMATH) ... CMATH Champions trip to Germany and Poland next week. , The Fourth Biennial CMATH ...
Breaking Medicine News(10 mins):
(Date:4/18/2017)... Ohio , April 18, 2017  Cardinal Health ... Non-GAAP 1 fiscal 2017 earnings per share (EPS) ... and 2019.  This is in conjunction with this morning,s ... Deep Vein Thrombosis and Nutritional Insufficiency businesses. ... from continuing operations will be at the bottom of ...
(Date:4/18/2017)... April 18, 2017 Research and Markets has ... report to their offering. ... The global arthroscopy devices market to grow at a CAGR of ... Arthroscopy Devices Market 2017-2021, has been prepared based on an in-depth ... market landscape and its growth prospects over the coming years. The ...
(Date:4/18/2017)...  Socionext Inc. and SOINN Inc. today announced ... which Socionext extracts and delivers biometrics data to ... results in reading ultrasound images from Socionext,s viewphii™ ... results will be introduced at Medtec Japan, held ... 4505 & 4507. In this initial ...
Breaking Medicine Technology: