Navigation Links
Steroid Concoction May Ease Sinusitis
Date:3/16/2009

Small study finds benefits, but drug does not have FDA approval for such use

MONDAY, March 16 (HealthDay News) -- A steroid nasal wash can help reduce symptoms of chronic sinusitis without affecting adrenal gland function, according to a small U.S. study.

Chronic sinusitis is a persistent inflammation of the nose and sinuses behind the nose that affects up to 14 percent of people in the United States, according to background information in the study.

The study included nine people who were told to use a nasal wash, composed of 0.25 milligrams of the corticosteroid budesonide and 5 milliliters of saline, in each nostril once a day for 30 days. The budesonide came in respules -- small, plastic, liquid-containing devices.

The researchers, from Washington University School of Medicine in St. Louis, said it was the first study to examine the safety of this type of nasal wash, noting that suppression of adrenal gland function is a known complication of budesonide.

All participants reported at least some improvement in their sinusitis symptoms, and their adrenal gland function was not affected, the study found. The results were published in the March issue of Otolaryngology -- Head & Neck Surgery.

"The clinical significance of this study is that budesonide nasal respules appear safe for short-term use for the relief of symptoms associated with chronic sinusitis," the researchers concluded. "Budesonide respules seem to provide an effective treatment option for the patient with chronic rhinosinusitis with minimal fear of systemic adverse effects."

The U.S. Food and Drug Administration has not approved budesonide as a nasal wash, which means the nasal wash used in this study would be an off-label use of the drug. The researchers urged doctors to warn patients about the risks associated with long-term use of budesonide, including decreased bone mineral density.

More information

The American Academy of Family Physicians has more about sinusitis.



-- Robert Preidt



SOURCE: JAMA/Archives journals, news release, March 16, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Steroids ineffective in young children with wheeze
2. 1 in 10 Ex-NFL Players Used Steroids, Poll Reports
3. Inhaled Corticosteroids Boost Pneumonia Risk in COPD
4. High and Super-High Potency Topical Corticosteroids Will Remain Decision Resources Clinical Gold Standard Through 2017 for the Treatment of Atopic Dermatitis
5. Additional Steroid Dose May Help Preemies
6. Twelve Indicted in Nationwide Anabolic Steroids Probe
7. Multiple Doses of Steroids Dont Help Preemies
8. Steroid After Tonsillectomy Raises Bleeding Risk
9. Steroid Inhalers Raise Pneumonia Risk for Lung Disease Patients
10. Study shows steroid therapies following transplant can be eliminated
11. Steroids aid recovery from pneumonia, UT Southwestern researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Steroid Concoction May Ease Sinusitis
(Date:10/13/2017)... ... October 13, 2017 , ... ... alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with ... for the primary prevention of cardiovascular diseases during the 15th Annual Women’s ...
(Date:10/13/2017)... York, NY (PRWEB) , ... October 13, 2017 , ... ... influential people in business to advocate for action towards gender equality at their inaugural ... views from around the globe, and reached a social audience of over 3 million. ...
(Date:10/13/2017)... , ... October 13, 2017 , ... “The Journey: From ... every danger possible to save lost souls in the Philippines. “The Journey: From the ... is a dedicated teacher of the Bible. She has taught all ages and currently ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has developed a ... and regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been ... standard. , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa Mohebi, the ... medical article to the newly revamped Cosmetic Town journal section, featuring ... transplant procedure known as Follicular Unit Extraction (FUE). , Dr. Mohebi ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... Pa. , Oct. 10, 2017   West ... in innovative solutions for injectable drug administration, today shared ... West,s ID Adapter for improving the intradermal administration of ... Fourth Skin Vaccination Summit in May 2017 by Dr. ... Lead, Polio Department, World Health Organization (WHO), and recently ...
(Date:10/4/2017)... , Oct. 4, 2017 ... single-use, self-contained, illuminating medical devices, today announced regulatory ... Health Surveillance Agency (or Agência Nacional de Vigilância ... first single-use, cordless surgical retractor with integrated LED ... optimal access, illumination and exposure of a tissue ...
(Date:10/2/2017)... , Oct. 2, 2017 The Rebound mobile ... the struggle to reverse the tide of prescription drug addiction. ... regulating their medicine intake and stepping down their dosage in ... to launch in December 2017; the first 100,000 people to ... more at http://www.rebound-solution.com/ ...
Breaking Medicine Technology: