Navigation Links
Steroid Can Ease Severe Sore Throat
Date:8/7/2009

Single dose speeds relief but should be reserved for worst cases, researchers say,,

FRIDAY, Aug. 7 (HealthDay News) -- A single dose of a corticosteroid, given along with antibiotics, can relieve severe sore throat pain faster and more effectively than antibiotics alone, a new study suggests.

"In people with severe sore throat, a single dose of an oral steroid is effective in relieving pain in 24 and 48 hours," said researcher Dr. Carl Heneghan, the deputy director of the Centre for Evidence-Based Medicine at the University of Oxford in the U.K.

This treatment is not advised for a mild sore throat, which will go away by itself, Heneghan stressed.

"If you turn up at your emergency department and you have really bad tonsillitis and you are in a lot of pain, an additional treatment is to take a single dose of a corticosteroid," he explained.

The report is published in the Aug. 7 online edition of BMJ.

Corticosteroids relieve pain by reducing inflammation and are commonly prescribed for conditions such as asthma and croup. Their use as a pain reliever for sore throat could help reduce the need for antibiotics, which can be overused and help create resistant bacteria, the U.K. researchers say.

For the study, Heneghan's group analyzed eight trials comparing the effectiveness of corticosteroids to placebo in adults or children with severe sore throats. In total, the studies included 743 patients, 369 of whom were children.

The researchers found that patients given corticosteroids plus antibiotics were three times more likely to report having no pain 24 hours after treatment compared with patients given antibiotics and a placebo.

After two days this effect was less apparent, which suggests that a single dose of corticosteroids is all that is needed, according to the researchers. In addition, corticosteroids also reduced the time it took to relieve pain by about six hours.

Heneghan's team noted that significant pain relief was only observed in adult patients and not in children receiving corticosteroids.

In addition, other painkillers made no difference in the results, the researchers found.

"What we don't know is: do corticosteroids replace antibiotics?" Heneghan stated. "That's another piece of research we would like to do," he said.

Dr. Julie Wei, an assistant professor of otolaryngology at the University of Kansas Medical Center, agreed that steroids work well in relieving severe sore throat pain, but she cautioned that they are not a substitute for antibiotics, which treat the infection, not the pain.

"The use of steroid should never be for the purpose of replacing antibiotics," Wei said. "Based on the current information, that is not the conclusion people should have."

Single-dose steroid use is already a common practice, Wei said. "For example, all my pediatric patients undergoing tonsillectomy and adenoidectomy get a single dose intravenously at the time of surgery, because steroids are the most potent anti-nausea, anti-vomiting medication we have," she said.

Single-dose steroids also help improve eating and drinking, and feeling good, Wei said. "Also, people in the emergency room or children admitted for throat abscess usually get a single dose of steroids if they are having severe pain or difficulty opening their mouth due to inflammation. We ENTs already recommend that commonly," she added.

"The bottom line is, it is already commonly used in anesthesia, ER setting, etc., but does not replace antibiotics," Wei said.

More information

For more information on sore throat, visit the U.S. National Library of Medicine.



SOURCES: Carl Heneghan, M.D., deputy director, Centre for Evidence-Based Medicine, University of Oxford, U.K.; Julie Wei, M.D., assistant professor of otolaryngology, University of Kansas Medical Center, Kansas City; Aug. 7, 2009, BMJ, online


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Steroids Seem Safe for Babies at Risk of Early Birth
2. Batters may achieve dramatic increases in home runs through steroids
3. Repeat steroids to premature infants linked to cerebral palsy
4. Multiple corticosteroid injections in pregnant women may increase cerebral palsy
5. International Law Enforcement Operation Targets Underground Manufacture of Anabolic Steroids
6. Steroids Are Abused for Skin, Not Just Muscles
7. Research Indicates Nearly 25 Percent of Supplements Are Contaminated With Steroids, Stimulants and Banned Substances
8. Steroid Fails to Ease Meningitis in Trials
9. Report Finds Widespread Steroid Use in Baseball
10. Pelosi Statement on Mitchell Report on Steroid Use in Baseball
11. Youth Impacted By Recent Mitchell Report on Major League Baseball Steroid Abuse
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2016)... San Diego, CA (PRWEB) , ... May 25, 2016 , ... There was a time ... more women are going with the flow and turning to menstrual cups, like Lunette ... a party, Lunette is introducing their new anthem in this catchy video ! ...
(Date:5/25/2016)... Indiana (PRWEB) , ... May 25, 2016 , ... ... Network Service Provider, announces that Lake City Bank has selected IFN as a ... manage carrier access, resulting in increased efficiencies and reduced costs. , ...
(Date:5/25/2016)... MA (PRWEB) , ... May 25, 2016 , ... ... Research Institute (WCRI) compare outcomes of injured workers across 15 states. The ... to work, earnings recovery, access to medical care, and satisfaction with medical care. ...
(Date:5/25/2016)... ... May 25, 2016 , ... CloudLIMS, joins an elite number of ... Tech Solution Providers list of 2016 by CIOReview. , In a deliberate session with ... Tech Solution Providers 2016 has been concluded with. The positioning is based on evaluation ...
(Date:5/25/2016)... ... May 25, 2016 , ... The World Molecular ... through Molecular Imaging.” The focus of ADDMI-IG will be geared towards how using ... pipeline issues. Through ADDMI-IG WMIS will provide a platform for productive discussions about ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... Marziani has joined VMS BioMarketing as senior vice president of sales, announced Andrea ... Marziani will lead the company,s business development and sales team, exploring new opportunities for ... - http://photos.prnewswire.com/prnh/20160523/371089 ... ... ...
(Date:5/24/2016)... 24, 2016 Open Access Journal ... Neurophysiology  Elsevier , a world-leading provider ... today announced the launch of Clinical Neurophysiology ... that focuses on clinical practice issues in clinical neurophysiology. ... series, normal values and didactic reviews. It is an ...
(Date:5/23/2016)... May 23, 2016 Global Paclitaxel ... pages, profiles 12 companies and the Paclitaxel analysis in ... on the industry and its players. This ... in nature, details the current state of the industry ... definitions, classifications, applications and industry chain structure. The Paclitaxel ...
Breaking Medicine Technology: