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Stereotactic radiosurgery shows promise for kidney cancer
Date:10/31/2012

CLEVELAND A first-of-its-kind clinical trial conducted at University Hospitals (UH) Case Medical Center Seidman Cancer Center has shown encouraging results for the use of stereotactic radiosurgery to treat kidney cancer. This non-invasive treatment technique may represent a potential new non-surgical option for patients with this deadly disease who have limited treatment options.

Rod Ellis, MD, lead author of the study along with Lee Ponsky, MD, who is the Principal Investigator, presented results of a Phase 1 clinical trial in 20 patients with localized primary renal cancer at the 54th Annual Meeting of the American Society for Radiation Oncology (ASTRO) in Boston. In the abstract titled "Stereotactic Radiosurgery for Renal Cancer: Phase I Safety and Toxicity" (embargoed Oct. 31, 7:00 am ET), Dr. Ellis presented data that 94 percent of patients treated in the study had decreased or stable disease, with limited side effects.

"This trial shows that low to moderate doses of stereotactic radiosurgery are safe for renal cancer patients who typically do not have surgical options," said Dr. Ellis, Clinical Director and Vice Chair for Clinical Affairs, Department of Radiation Oncology at UH Case Medical Center and Associate Professor of Radiation Oncology and Urology at Case Western Reserve University School of Medicine. "Based on these findings, this treatment represents a promising therapeutic option. Further studies are needed to determine safe levels for the maximum dosage and by doing so, we hope to find increased response and cure rates with this method."

"This study is a unique partnership between a surgeon and radiation oncologist, intended to offer patients a non-invasive, highly focused ablative radiation with surgical precision with little to no side effects," said Dr. Ponsky, Director, Urologic Oncology and Minimally Invasive Therapies at UH Case Medial Center and Associate Professor of Urology at Case Western Reserve School of
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Contact: Alicia Reale
alicia.reale@uhhospitals.org
216-844-5158
University Hospitals Case Medical Center
Source:Eurekalert

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