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Steno 'Superbug' Genome Shows Extreme Drug Resistance
Date:5/9/2008

tems are already weakened. Since the new research shows Steno to be largely resistant to antibiotics, these patients face an extremely difficult situation.

"The genome sequence should help us to combat these properties," lead author Dr. Lisa Crossman, of the Wellcome Trust Sanger Institute near Cambridge, said in a prepared statement. "For example, if we know which proteins cause it to stick to surfaces, we could try to develop biochemical compounds that interfere with this interaction. If we understand its antibiotic resistance mechanisms, we might be able to design inhibitors that block them."

Researchers also hope that since Steno causes similar types of infections to two more common organisms, they can find solutions by comparing the two.

"Genome sequences for these two also exist, and so now we can look at what they all have in common genetically that might explain why they are so resistant to antibiotics," Avison said.

More information

The U.S. Centers for Disease Control has more about drug-resistant bacteria.



-- Kevin McKeever



SOURCE: University of Bristol, news release, May 7, 2008


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